Material Substrate Physical Properties Control Pseudomonas aeruginosa Biofilm Architecture

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Background Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclei ...

BMC2023

The biofilm ecology of proglacial floodplain streams

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Glacial forelands figure among the most dynamic landscapes on Earth, and their formation is currently accelerating given glacier shrinkage. Draining these forelands are streams hosting unique microbial communities, which have the capacity to impact both th ...

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Homogeneous Environmental Selection Structures the Bacterial Communities of Benthic Biofilms in Proglacial Floodplain Streams

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Streams draining proglacial floodplains harbor benthic biofilms comprised of diverse microbial communities. These high-mountain ecosystems are rapidly changing with climate warming, and it is therefore critical to better understand the mechanisms underlyin ...

AMER SOC MICROBIOLOGY2023

Functional characterization of Drosophila melanogaster immune effectors

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Drosophila melanogaster, commonly known as the "fruit fly", is a genetically tractable model organism widely used to study biological processes, notably the innate immune system. The advent of novel genome editing technologies, such as the CRISPR-Cas9 syst ...

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Characterization of Pseudomonas aeruginosa mechanosensing through label-free imaging of type IV pili

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Bacteria are ubiquitously found in all sorts of environment. They're found in the ocean, soil, or even in our guts or on our skin. Independently of their niche, they can transition from a planktonic state were they freely swim in an aqueous environment to ...

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Natural competence of the pathogen Acinetobacter baumannii: an elusive phenomenon

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Natural competence for transformation is an important driver of horizontal DNA exchange between different organisms. This can result in accumulation of dangerous genetic features, such as antibiotic resistance genes, in a single organism. One example of an ...

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Photodynamic treatment of multidrug-resistant bacterial infection using indium phosphide quantum dots

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Infections caused by multidrug-resistant (MDR) bacteria pose an impending threat to humanity, as the evolution of MDR bacteria outpaces the development of effective antibiotics. In this work, we use indium phosphide (InP) quantum dots (QDs) to treat infect ...

ROYAL SOC CHEMISTRY2022