Fluorine in an heteroaromatic context : functionalization of halopyridines

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Lignin is an abundant renewable carbon source. Due to its complex structure, utilization of lignin is very challenging. Herein, we describe an efficient strategy for the simultaneous utilization of lignin, in which the methoxy groups in lignin react with c ...

The development of a sequential copper-catalyzed oxy-alkynylation/intramolecular [4+2] cycloaddition of allenes and arenes was investigated at first. This one-pot protocol allowed the construction of complex polycylic architectures with high efficiency fro ...

Over the past twenty years, photochemical transformations have gained in importance in organic chemistry. Indeed, the development of photocatalysts has allowed the use of visible light as an energy source for chemical transformations. More specifically, ph ...

Nitrous oxide (N2O) has gained much interest because of its physiological effects ("laughing gas") and its negative environmental impact ("greenhouse gas", "ozone-depleting substance"): It has a lifetime of more than 100 years in the atmosphere. Its persis ...

Amino alcohols, cyclopropanes and nitriles are privileged structural motifs found in the scaffold of natural products and bioactive compounds. In addition, they are versatile building blocks in organic chemistry. The development of new and increasingly eff ...

Superconductor/metal interfaces are usually fabricated in heterostructures that join these dissimilar materials. A conceptually different approach has recently exploited the strain sensitivity of heavy-fermion superconductors, selectively transforming regi ...

This paper provides accurate analytic models for a computationally efficient estimation of the natural con- vection cooling coefficients for typical geometries, such as those encountered in transformers. Proper thermal coordination is an essential step of ...

Design of Integrally-Attached Timber Plate Structures outlines a new design methodology for digitally fabricated spatial timber plate structures, presented with examples from recent construction projects. It proposes an innovative and sustainable design me ...

Ethynylbenziodoxol(on)e (EBX) cyclic hypervalent iodine reagents have become popular reagents for the alkynylation of radicals and nucleophiles, but only offer limited possibilities for further structure and reactivity fine-tuning. Herein, the synthesis of ...

Five-membered heterocycles are well known for their innate nucleophilicity. In contrast, reaction of these heterocycles as electrophiles is less established and has become only recently an intensively investigated research area in synthetic chemistry. The ...

When exposed to a thermal gradient, reaction networks can convert thermal energy into the chemical selection of states that would be unfavourable at equilibrium. The kinetics of reaction paths, and thus how fast they dissipate available energy, might be do ...

Diamines are essential building blocks for the synthesis of agrochemicals, drugs, and organic materials, yet their synthesis remains challenging, as both nitrogens need to be differentiated and diverse substitution patterns (1,2, 1,3, or 1,4) are required. ...

The 2-pyrone motif occurs frequently in bioactive natural products and is appreciated as synthetic intermediates. However, only few methods allow for diversifying functional group modifications on this relevant heterocycle. The distinct properties of 1-alk ...

We report an oxidative ring-opening strategy to transform cyclopropylamides and cyclobutylamides into fluorinated imines. The imines can be isolated in their more stable hemiaminal form, with the fluorine atom installed selectively at the gamma or delta po ...

Ethynylbenziodoxolones (EBXs) are commonly encountered reagents for the electrophilic alkynylation of nucleophiles. Herein, we report a one-pot, two-step process for EBX generation and their direct application in substrate functionalization. Our approach e ...

Fluorine in an heteroaromatic context : functionalization of halopyridines

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Simultaneous Generation of Methyl Esters and CO in Lignin Transformation

New Vinylation and Alkynylation Strategies with Hypervalent Iodine Reagents and Diazo Compounds

Photochemical Alkynylations with Hypervalent Iodine Reagents

Synthetic chemistry with nitrous oxide and triazenes

New Strategies for the Functionalization of Alkenes Exploiting Tethering Chemistry and Ring Strain

Controlling superconductivity of CeIrIn5 microstructures by substrate selection

Improved Natural-Air-Convection-Cooling Formulas for Medium Frequency Transformer Design Optimization

Design of Integrally-Attached Timber Plate Structures

Structure and Reactivity of N-Heterocyclic Alkynyl Hypervalent Iodine Reagents

Umpolung Of Electron-Rich Heteroarenes With Hypervalent Iodine Reagents

Dissipation-Driven Selection under Finite Diffusion: Hints from Equilibrium and Separation of Time Scales

Diamine Synthesis via the Nitrogen-Directed Azidation of sigma- and pi-C-C Bonds

Alkynyl triazenes enable divergent syntheses of 2-pyrones

Oxidative Fluorination of Cyclopropylamides through Organic Photoredox Catalysis

Tosyloxybenziodoxolone: A Platform for Performing the Umpolung of Alkynes in One-Pot Transformations