The effect of lactose-conjugated silk biomaterials on the development of fibrogenic fibroblasts

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The largest source of systematic errors in the time-delay cosmography method likely arises from the lens model mass distribution, where an inaccurate choice of model could in principle bias the value of H-0. A Bayesian hierarchical framework has been propo ...

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

Sustained exposure to a young systemic environment rejuvenates aged organisms and promotes cellular function. However, due to the intrinsic complexity of tissues it remains challenging to pinpoint niche-independent effects of circulating factors on specifi ...

At the current time, the world as we know it is at a crossroads; there is an urgent need to lower greenhouse gas emissions to limit the global rise in temperature. However, this is at odds with the increasing energy demands of the world's growing populatio ...

The development of sustainable urban projects is crucial to address the challenges of the growing population living in cities. Facing complex decision-making and increasing expectations from inhabitants, local institutions are gradually becoming open to co ...

The resolving power, chemical sensitivity and non-invasive nature of NMR have made it an established technique for in vivo studies of large organisms both for research and clinical applications. NMR would clearly be beneficial for analysis of entities at t ...

Background Few studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation and the findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated the interaction effect of neig ...

Therapies to accelerate vascular repair are currently lacking. Pre-clinical studies suggest that hydrogen sulfide (H2S), an endogenous gasotransmitter, promotes angiogenesis. Here, we hypothesized that sodium thiosulfate (STS), a clinically relevant source ...

The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor in the SYSCOL cohort, we ...

In humans, mice, and other mammals key internal organs such as the gut, the lungs, the pancreas, and the liver all derive from the same embryonic tissue: the endoderm. The development of all of these structures thus depends on a same set of early cells, an ...

Single-walled carbon nanotubes (SWCNTs) emit photostable near-infrared fluorescence that is conducive for optical glucose monitoring. Such SWCNT-based optical sensors often require the immobilization of proteins that can confer glucose selectivity and reac ...

Activin-A, a transforming growth factor ê µ family member, is a pleiotropic cytokine with diverse functions in development, fertility, adult tissue homeostasis, and aging. Accordingly, deregulation of Activin-A signaling has been associated with many patho ...

The effect of lactose-conjugated silk biomaterials on the development of fibrogenic fibroblasts

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TOCOSMO VIII. A key test of systematics in the hierarchical method of time-delay cosmography

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

In vivo transcriptomic profiling using cell encapsulation identifies effector pathways of systemic aging

Unravelling the mechanism of ultrafast photoinduced charge generation in organic and hybrid photovoltaic systems

The Future of Civic Technologies for the Involvement of Citizens in Urban Planning: 3D Urban Participatory e-Planning in the Spotlight

NMR spectroscopy of a single mammalian early stage embryo

Association of neighbourhood disadvantage and individual socioeconomic position with all-cause mortality: a longitudinal multicohort analysis

Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture

Bioengineering a glucose oxidase nanosensor for near-infrared continuous glucose monitoring

Immunosuppressive roles of Activin-A in melanoma and characterization of its precursor cleavage