A template for constructing Bayesian networks in forensic biology cases when considering activity level propositions

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The field of protein design has made remarkable progress over the past decade. Historically, the low reliability of purely structure-based design methods limited their application, but recent strategies that combine structure-based and sequence-based calcu ...

The increasing demand for computing power and the emergence of heterogeneous computing architectures have driven the exploration of innovative techniques to address current limitations in both the compute and memory subsystems. One such solution is the use ...

Translation elongation plays an important role in regulating protein concentrations in the cell, and dysregulation of this process has been linked to several human diseases. In this study, we use data from ribo-seq experiments to model ribosome densities, ...

Post-translational modifications (PTMs) play a pivotal role in regulating protein structure, interaction, and function. Aberrant PTM patterns are associated with diseases. Moreover, individual PTMs have a complex interaction with each other, known as PTM c ...

We initiate the study of certain families of L-functions attached to characters of subgroups of higher-rank tori, and of their average at the central point. In particular, we evaluate the average of the values L( 2 1 , chi a )L( 21 , chi b ) for arbitrary ...

We propose a new approach for normalization and simplification of logical formulas. Our approach is based on algorithms for lattice-like structures. Specifically, we present two efficient algorithms for computing a normal form and deciding the word problem ...

Public policy evaluation has traditionally been conducted in a context constrained by legal, institutional and political red tape. The arrival of digitalisation adds a new layer to public policy evaluation processes. Assessing the quality of technologies, ...

File formats are described in read_me files in the concerning folder. For plotting and data evaluation, Python 2.7 was used. Example scripts for plotting are provided. ...

Language has shaped human evolution and led to the desire to endow machines with language abilities. Recent advancements in natural language processing enable us to achieve this breakthrough in human-machine interaction. However, introducing conversational ...

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Tantalum is receiving increasing attention in the biomedical field due to its biocompatible nature and superior mechanical properties. However, the bioinert nature of tantalum still poses a challenge and limits its integration into the bone tissue. To addr ...

Virtual Memory (VM) is a critical programming abstraction that is widely used in various modern computing platforms. With the rise of datacenter computing and birth of planet-scale online services, the semantic and capacity requirements from memory have ev ...

Native reactive electrophilic species (RES) are long-recognized regulators of pathophysiology; yet, knowledge surrounding how RES regulate context-specific biology remains limited. The latest technological advances in profiling and precision decoding of RE ...

Exploring a wide range of design options is crucial for every sound conceptual design process. In the conventional structural design workflow, optimization techniques are generally employed to generate well-performing design options. However, focusing only ...

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Proteins, the central building blocks of life, play pivotal roles in nearly every biological function. To do so, these macromolecular structures interact with their surrounding environment in complex ways, leading to diverse functional behaviors. The predi ...

De novo protein design enhances our understanding of the principles that govern protein folding and interactions, and has the potential to revolutionize biotechnology through the engineering of novel protein functionalities. Despite recent progress in comp ...

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Before the twentieth century and concrete modernity, it was stone that embodied the “well built”. Could sustainable wood one day replace concrete as the archetypal material? Will it find a place on the scale of values that gives archi- tecture its referenc ...

A template for constructing Bayesian networks in forensic biology cases when considering activity level propositions

Chattez avec Graph Search

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Toroidal families and averages of L-functions, I

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