Reply to comments on "Explicit versus implicit front advancing schemes for the simulation of hydraulic fracture growth" (Int. J. Numer. Anal. Methods Geomech., 2019, 43 (6), 1300-1315)" by Prof. Linkov

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Impact of individual differences in glucocorticoid adaptation to stress on behavior, neurophysiology and metabolism

Damien Sébastien Huzard

The stress system is a key modulator of homeostasis and allows organisms to adapt to environmental changes. Proper survival is dependent on the appropriate stress response, for example initiating food (energy) intake or provoking physical reaction. However ...

EPFL2018

Music influences vividness and content of imagined journeys in a directed visual imagery task

Ken Jacques Alfonso Deguernel, Steffen Alexander Herff, Gabriele Cecchetti

Directed, intentional imagination is pivotal for self-regulation in the form of escapism and therapies for a wide variety of mental health conditions, such anxiety and stress disorders, as well as phobias. Clinical application in particular benefits from i ...

Nature Portfolio2021

An energetic view of stress: Focus on mitochondria

Maria del Carmen Sandi Perez

Energy is required to sustain life and enable stress adaptation. At the cellular level, energy is largely derived from mitochondria – unique multifunctional organelles with their own genome. Four main elements connect mitochondria to stress: 1) Energy is r ...

2018

Proposed methodology for building-specific earthquake loss assessment including column residual axial shortening

Dimitrios Lignos, Ahmed Mohamed Ahmed Elkady

This paper proposes methodological developments for quantifying the impact of residual axial shortening of first-story steel columns on earthquake loss estimations in steel moment-resisting frame (MRF) buildings. A new formulation is proposed that accounts ...

2020

Nano-photonic Supercontinuum Based Mid-Infrared Dual-Comb Spectroscopy

Luc Thévenaz, Tobias Kippenberg, Camille Sophie Brès, Junqiu Liu, Hairun Guo, Wenle Weng, Fan Yang

We demonstrate an approach to dual-comb spectroscopy, based on dispersion engineered and ultra-broadband supercontinuum generation in photonic integrated nonlinear waveguides, and driven by low-noise fiber-laser combs. Both technologies arc statc-of-the-ar ...

IEEE2020

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Aurélie Lattion

Play fighting is a highly rewarding behavior that helps individuals to develop social skills. Early-life stress has been shown to alter play fighting in rats and hamsters as well as to increase aggressive behaviors at adulthood. However, it is not known wh ...

2018

Compressive Strength and Deformation Capacity of Concrete under Sustained Loading and Low Stress Rates

Aurelio Muttoni, Miguel Fernández Ruiz, Darko Tasevski

This paper investigates the behaviour of concrete failing under high stress levels and subjected to different types of loading. The aim of this investigation is to clarify the development of linear and nonlinear creep strains and how they relate to materia ...

2018

Assessment of the breakthrough of micropollutants in full-scale granular activated carbon adsorbers by rapid small-scale column tests and a novel pilot-scale sampling approach

Urs von Gunten

This study aimed to compare three approaches for predicting the service life of full-scale GAC adsorbers for the removal of micropollutants. The approaches included (i) rapid small-scale column tests (RSSCTs), (ii) two pilot-scale sampling approaches, and ...

ROYAL SOC CHEMISTRY2020

Programming effects of peripubertal stress on spatial learning

Maria del Carmen Sandi Perez, Stamatina Tzanoulinou

Exposure to adversity during early life can have profound influences on brain function and behavior later in life. The peripubertal period is emerging as an important time-window of susceptibility to stress, with substantial evidence documenting long-term ...

2020

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

João Miguel das Neves Duarte, Alberto Corcoba

Adverse environmental and social conditions early in life have a strong impact on health. They are major risk factors for mental diseases in adulthood and, in some cases, their effects can be transmitted across generations. The consequences of detrimental ...

Sage Publications Inc2017