Publication

Reply to comments on "Explicit versus implicit front advancing schemes for the simulation of hydraulic fracture growth" (Int. J. Numer. Anal. Methods Geomech., 2019, 43 (6), 1300-1315)" by Prof. Linkov

Publications associées (31)

Neurobiological links between stress and anxiety

Stress and anxiety have intertwined behavioral and neural underpinnings. These commonalities are critical for understanding each state, as well as their mutual interactions. Grasping the mechanisms underlying this bidirectional relationship will have major ...

2019

On the definition of an effective stress for shales

Lyesse Laloui, Alessio Ferrari, Angelica Tuttolomondo

Energy-related engineering applications involving shales pose ever-increasing challenges for the constitutive modelling of these geomaterials. The present work proposes a new definition of effective stress developed by using a thermodynamic approach associ ...

2019

An Effective Stress Framework for Clayey Geomaterials Including a Chemical-Dependent Variable

Lyesse Laloui, Alessio Ferrari, Angelica Tuttolomondo

Experimental evidence shows that the chemical composition of the liquid inside the pores and its variation over time can have significant implications on the mechanical and hydraulic behavior of clayey geomaterials. The magnitude of these implications depe ...

2019

Low vagal tone in two rat models of psychopathology involving high or low corticosterone stress responses

Maria del Carmen Sandi Perez, Damien Sébastien Huzard, Jocelin Grosse, Sriparna Ghosal

The two stress-responsive physiological systems, autonomic nervous system (ANS) and hypothalamus-pituitary-adrenal (HPA) axis exert complementary and interrelated actions in the organism. Individuals that suffer stress-related psychopathologies frequently ...

2019

Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities

Maria del Carmen Sandi Perez, Eleni Vasilaki, Damien Sébastien Huzard, Simone Astori

The stress response facilitates survival through adaptation and is intimately related to cognitive processes. The Morris water maze task probes spatial learning and memory in rodents and glucocorticoids (i.e. corticosterone (CORT) in rats) have been sugges ...

2020

Long term programming of psychopathology-like behaviors in male rats by peripubertal stress depends on individual’s glucocorticoid responsiveness to stress

Maria del Carmen Sandi Perez, Sophie Elizabeth Walker

Experience of adversity early in life and dysregulation of hypothalamus–pituitary–adrenocortical (HPA) axis activity are risk factors often independently associated with the development of psychopathological disorders, including depression, PTSD and pathol ...

2018

Impact of individual differences in glucocorticoid adaptation to stress on behavior, neurophysiology and metabolism

Damien Sébastien Huzard

The stress system is a key modulator of homeostasis and allows organisms to adapt to environmental changes. Proper survival is dependent on the appropriate stress response, for example initiating food (energy) intake or provoking physical reaction. However ...

EPFL2018

An energetic view of stress: Focus on mitochondria

Maria del Carmen Sandi Perez

Energy is required to sustain life and enable stress adaptation. At the cellular level, energy is largely derived from mitochondria – unique multifunctional organelles with their own genome. Four main elements connect mitochondria to stress: 1) Energy is r ...

2018

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala

Maria del Carmen Sandi Perez, Olivia Zanoletti, Jocelin Grosse

Play fighting is a highly rewarding behavior that helps individuals to develop social skills. Early-life stress has been shown to alter play fighting in rats and hamsters as well as to increase aggressive behaviors at adulthood. However, it is not known wh ...

2018

Compressive Strength and Deformation Capacity of Concrete under Sustained Loading and Low Stress Rates

Aurelio Muttoni, Miguel Fernández Ruiz, Darko Tasevski

This paper investigates the behaviour of concrete failing under high stress levels and subjected to different types of loading. The aim of this investigation is to clarify the development of linear and nonlinear creep strains and how they relate to materia ...

2018

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

João Miguel das Neves Duarte, Alberto Corcoba

Adverse environmental and social conditions early in life have a strong impact on health. They are major risk factors for mental diseases in adulthood and, in some cases, their effects can be transmitted across generations. The consequences of detrimental ...

Sage Publications Inc2017