Publications associées à Back to the future–20 years of progress and developments in photonic microscopy and biological imaging

Publications associées (13)

Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera

Edoardo Charbon, Claudio Bruschini, Aleksandra Radenovic, Matteo Dal Peraro, Nathan Cyprien Arsène Ronceray, Marianna Fanouria Mitsioni

Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool to discriminate fluorescent molecules or probe their nanoscale environment. Traditionally, FLIM uses time-correlated single-photon counting (TCSPC), which is precise but intrinsically low-t ...

2025

Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution

Henning Paul-Julius Stahlberg, Kelvin Ka Ching Lau

Cryo-transmission electron microscopy (cryo-EM) of frozen hydrated specimens is an efficient method for the structural analysis of purified biological molecules. However, cryo-EM and cryo-electron tomography are limited by the low signal-to-noise ratio (SN ...

Nature Research2024

Self-supervised Dense Representation Learning for Live-Cell Microscopy with Time Arrow Prediction

Martin Weigert, Benjamin Tobias Gallusser

State-of-the-art object detection and segmentation methods for microscopy images rely on supervised machine learning, which requires laborious manual annotation of training data. Here we present a self-supervised method based on time arrow prediction pre-t ...

Springer International Publishing Ag2023

Weakly supervised joint whole-slide segmentation and classification in prostate cancer

Seyedbehzad Bozorgtabar, Guillaume Jaume

The identification and segmentation of histological regions of interest can provide significant support to pathologists in their diagnostic tasks. However, segmentation methods are constrained by the difficulty in obtaining pixel-level annotations, which a ...

ELSEVIER2023

Atomic-scale Characterization of Strain and Gate effects on Two-dimensional Materials by Scanning Tunneling Microscopy

Jz -Yuan Juo

Strain is an inevitable phenomenon in two-dimensional (2D) material, regardless of whether the film is suspended or supported. Moreover, strain is known to alter the physical and chemical properties, such as the band gap, charge carrier effective masses, d ...

EPFL2023

Concrete cancer : characterization of Alkali Silica Reaction early stage products by electron microscopy

Solène Anne-Lise Albinski

Concrete deterioration is a natural process, which has to be carefully monitored over a the service life of a structure. The Alkali-Silica Reaction (ASR) is a slow-process degradation, which devel-ops over decades and is therefore difficult to predict. Sin ...

EPFL2022

Strength can be controlled by edge dislocations in refractory high-entropy alloys

William Curtin, Francesco Maresca

Energy efficiency is motivating the search for new high-temperature (high-T) metals. Some new body-centered-cubic (BCC) random multicomponent "high-entropy alloys (HEAs)" based on refractory elements (Cr-Mo-Nb-Ta-V-W-Hf-Ti-Zr) possess exceptional strengths ...

Nature Portfolio2021

Marker-Free Automatic Quantification of Drug-Treated Cardiomyocytes with Digital Holographic Imaging

Pierre Marquet, Gerardo Turcatti, Benjamin Rappaz, Fabien Kuttler, Bokyoung Kim

We use quantitative phase digital holographic microscopy (QP-DHM) to image and quantify the beating movement of cardiomyocytes, derived from induced pluripotent stem cells (iPSCs), in control and drug-treated conditions. The development of an analysis algo ...

AMER CHEMICAL SOC2020

A Modular, Direct Time-of-Flight Depth Sensor in 45/65-nm 3-D-Stacked CMOS Technology

Edoardo Charbon, Myung Jae Lee, Preethi Padmanabhan, Augusto Ronchini Ximenes

This article introduces a modular, direct time-of-flight (TOF) depth sensor. Each module is digitally synthesized and features a 2

\times

(8

\times

8) single-photon avalanche diode (SPAD) pixel array, an edge-sensitive decision tree, a shared time-to ...

2019

Fast multiscale reconstruction for Cryo-EM

Michaël Unser, Masih Nilchian, Laurène Donati

We present a multiscale reconstruction framework for single-particle analysis (SPA). The representation of three-dimensional (3D) objects with scaled basis functions permits the reconstruction of volumes at any desired scale in the real-space. This multisc ...

Elsevier2018

Automated Eardrum Registration From Light-Field Data

Pascal Frossard, Ivana Tosic, Sofia Karygianni

The performance of automated classification algorithms for medical images needs to be very high and especially robust in order to be adopted into healthcare. Most of the time the main challenge is unregistered data, since it is usually captured: 1) from di ...

IEEE2018

Improved Labeling of Pancreatic Islets Using Cationic Magnetoliposomes

Ting Yin

Pancreatic islets (PIs) transplantation is an alternative approach for the treatment of severe forms of type 1 diabetes (T1D). To monitor the success of transplantation, it is desirable to follow the location of engrafted PIs non-invasively. In vivo magnet ...

MDPI2018

Is desiccation tolerance and avoidance reflected in xylem and phloem anatomy of two coexisting arid-zone coniferous trees?

Alessandra Patera

Plants close their stomata during drought to avoid excessive water loss, but species differ in respect to the drought severity at which stomata close. The stomatal closure point is related to xylem anatomy and vulnerability to embolism, but it also has imp ...

2018