A general method for the development of multicolor biosensors with large dynamic ranges

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Innate immunity, the very first line of defence of our cells, relies on the detection of universal pathogen- or danger-associated signals to launch an inflammatory response. A crucial part of our innate immune system is based on the recognition of out-of-c ...

Microscopic visualisation of optically transparent samples has been a topic of interest for several decades. Features such as density or chemical composition can influence the optical phase of transmitted light, and phase contrast can reveal these structur ...

Hypervalent iodine compounds are powerful reagents for the development of novel transformations. As they exhibit low toxicity, high functional group tolerance, and stability in biocompatible media, they have been used for the functionalization of biomolecu ...

Measuring the high-affinity binding of proteins to liposome membranes remains a challenge. Here, we show an ultrasensitive and direct detection of protein binding to liposome membranes using high throughput second harmonic scattering (SHS). Perfringolysin ...

Current microscopy systems for the imaging of microorganisms are expensive because of their optimized design toward resolution maximization and aberration correction. In situations where such an optimization is not needed, for instance to merely detect the ...

Amongst the substances found in any living organism one of the most central in the workings of each living cell is deoxyribonucleic acid (DNA). For that reason it has been the subject of research in many of its aspects. These range from DNA sequencing to a ...

Lighting has an impact on the visual as well as cognitive performance of people in non-residential buildings. Light is the most powerful time cue for resetting the circadian pacemaker and ensuring correct synchronization of the internal clock with the envi ...

The absorption of dietary calcium through the intestinal barrier is essential for maintaining health in general and especially of the bone system. We propose a microfluidic model that studies free calcium (Ca2+) transport through a confluent monolayer of C ...

The invention pertains to a near-infrared fluorescent dye that is cell permeable and can be attached to selected proteins in living cells. The dye has the general formula (I) or its or its corresponding spirolactone (II) wherein Y is chosen from the group ...

Nonlinear optical nanocrystals have been recently introduced as a promising alternative to fluorescent probes for multi-photon microscopy. We present for the first time a complete survey of the properties of the different nanomaterials proposed to date, de ...

A general method for the development of multicolor biosensors with large dynamic ranges

Chattez avec Graph Search

Tracking spatiotemporal localisation and interactions of the innate immune sensor STING

High sensitivity, incoherent differential imaging

Hypervalent Iodine-Mediated Late-Stage Peptide and Protein Functionalization

Ultrasensitive Label-Free Detection of Protein–Membrane Interaction Exemplified by Toxin-Liposome Insertion

Integration of polymeric membrane/dielectric sphere assemblies in microfluidic chips for enhanced-contrast imaging with low-magnification systems

Computation and Visualization in Multiscale Modelling of DNA Mechanics

On the Impact of Integration of Non-Image Forming (NIF) Effect of Light on Electrical Lighting Control in Non-Residential Buildings

Microfluidic chip for monitoring Ca2+ transport through a confluent layer of intestinal cells

Cell permeable, fluorescent dye

Harmonic Nanocrystals for Bio-Labeling: a Survey of Optical Properties and Biocompatibility