Publications associées à Building up Resilience in a Pharmaceutical Supply Chain through Inventory, Dual Sourcing and Agility Capacity

Publications associées (33)

Can one hear the shape of a target zone?

We develop an exchange rate target zone model with finite exit time and non-Gaussian tails. We show how the tails are a consequence of time-varying investor risk aversion, which generates mean-preserving spreads in the fundamental distribution. We solve ex ...

2023

Technology Strategy in Dynamic Environments: A Computational Analysis of the Automation of Routines, the Organization of AI, and the Evaluation of Technology Risk

Maximilian Wieland Hofer

In this dissertation, I develop theory and evidence to argue that new technologies are central to how firms organize to create and capture value. I use computational methods such as reinforcement learning and probabilistic topic modeling to investigate thr ...

EPFL2022

An arbitrary-order Cell Method with block-diagonal mass-matrices for the time-dependent 2D Maxwell equations

Bernard Kapidani

We introduce a new numerical method for the time-dependent Maxwell equations on unstructured meshes in two space dimensions. This relies on the introduction of a new mesh, which is the barycentric-dual cellular complex of the starting simplicial mesh, and ...

2021

High Performance Computing for gravitational lens modeling: Single vs double precision on GPUs and CPUs

Jean-Paul Richard Kneib, Markus Rexroth, Christoph Ernst René Schäfer

Strong gravitational lensing is a powerful probe of cosmology and the dark matter distribution. Efficient lensing software is already a necessity to fully use its potential and the performance demands will only increase with the upcoming generation of tele ...

ELSEVIER2020

Managing Risks when Using Nanomaterials in Research

Thierry Meyer, Amela Groso, Anna Maria Novello, Elina Buitrago

As the number of engineered nanomaterials (ENM) used in research increases with an incredible speed, health and safety specialists are continuously faced with the challenge of evaluating the risks involved with these materials. Nowadays there is not enough ...

2019

Are insurance balance sheets carbon-neutral? Harnessing asset pricing for climate change policy(dagger)

Jiahua Xu

Due to its enormous size and capital base, the insurance industry has the potential to play a key role in countering climate change. To this end, the major capital flows associated with its investment and underwriting businesses would need to be redirected ...

PALGRAVE MACMILLAN LTD2019

A Framework to Evaluate the Benefit of Seismic Upgrading

Pierino Lestuzzi

The framework to evaluate the benefit of seismic upgrading of Galanis et al. (2018) is compared to that present in the Swiss seismic code for existing buildings since 2004, updated in 2017. To illustrate the comparison, the example building of Galanis et a ...

2019

EaRL: Toolbox for Earthquake Risk and Loss Assessment of Building Assets

Dimitrios Lignos, Ahmed Mohamed Ahmed Elkady, Seong-Hoon Hwang

Infrastructure (asset) risk management is essential for a resilient environment. Several industries are concerned to improve their building asset preparedness subject to seismic hazard. To this end, the development of software tools that quantify and asses ...

2018

Financial Stability and the Macroeconomy : the Role of Bank Liquidity Regulation and Deposit Insurance

Corinne Dubois

The financial crisis of 2007-2009 drew attention to the essential role of banks for the macroeconomy and to the importance of having a resilient financial sector. A vulnerability in the financial sector spills over to the real economy and can drive it into ...

EPFL2018

Risk perception and decision-making: do farmers consider risks from climate change?

Claudia Rebeca Binder Signer

Small-scale farmers are highly threatened by climate change. Experts often base their interventions to support farmers to adapt to climate change on their own perception of farmers' livelihood risks. However, if differences in risk perception between farme ...

SPRINGER2018

Shape constrained splines as transparent black-box models for bioprocess modeling

Dominique Bonvin, Julien Léo Billeter, Sriniketh Srinivasan

Empirical model identification for biological systems is a challenging task due to the combined effects of complex interactions, nonlinear effects, and lack of specific measurements. In this context, several researchers have provided tools for experimental ...

Elsevier2017

Strengthening of high entropy alloys by dilute solute additions: CoCrFeNiAlx and CoCrFeNiMnAlx alloys

William Curtin, Céline Varvenne

A theory to predict the initial flow stress of an arbitrary N-component fcc random alloy is extended to predict the additional strengthening when a dilute concentration of a substitutional element is introduced. Assuming properties for the N-component allo ...

2017

Introduction to the IRGC Risk Governance Framework

Marcel Thomas Bürkler, Marie-Valentine Renée Agnès Florin

The IRGC Framework recommends a holistic, multidisciplinary and multistakeholder approach to risk. It supports processes that aim to provide and structure scientific evidence about a risk in a societal context. It helps decision-makers analyse the major am ...

EPFL2017

Incorporating model uncertainty into optimal insurance contract design

Anna Timonina-Farkas

In stochastic optimization models, the optimal solution heavily depends on the selected probability model for the scenarios. However, the scenario models are typically chosen on the basis of statistical estimates and are therefore subject to model error. W ...

Elsevier2017

Effects of aging in dry environment on physical and mechanical properties of a cold-curing structural epoxy adhesive for bridge construction

Thomas Keller, Anastasios Vassilopoulos, Maria Savvilotidou

The effect of physical aging and continuation of curing on the physical and mechanical properties of a commercial cold-curing structural epoxy adhesive used in bridge construction has been investigated during the first year. Since adhesive bridge joints ar ...

Elsevier2017

Higher-order continuation method for the rigid-body kinematic design of compliant mechanisms

Simon Nessim Henein, Lennart Rubbert

Compliant mechanisms are of great interest in precision engineering. In this paper we propose a higher order continuation method to help their rigid-body kinematic design. The method helps to investigate the choice of a mechanism configuration through the ...

2017

Green paper-based piezoelectronics for sensors and actuators

Danick Briand, Etienne Pierre Lemaire, Christopher John Borsa

We report a novel biodegradable piezoelectric composite fabricated from paper and the piezoelectric salt, sodium potassium tartrate tetrahydrate (Rochelle salt, which we term PiezoSalt). The piezoelectric composite is non-toxic and is fabricated free of en ...

Elsevier2016

Le processus de projet dans la reconstruction urbaine suite à une catastrophe

Julien Grisel

This study analyzes three project process for the reconstruction of urban areas destroyed by natural disaster or armed conflict: the village of Gondo in Switzerland, partially destroyed by a landslide, has been refurbished following an architectural compet ...

EPFL2010

Improving Risk Regulation

Marie-Valentine Renée Agnès Florin

Confronted with the challenge of improving regulatory performance, many governments in the world are looking for ways to better manage risks, in particular those risks that develop in complex systems, with stakeholders from various sectors, and that are ma ...

International Risk Governance Council (IRGC)2015

Cadmium accumulation in six common plant species associated with soils containing high geogenic cadmium concentrations at Le Gurnigel, Swiss Jura Mountains

François Gillet

The uptake of cadmium (Cd) was analyzed for six different perennial plant species growing in a wooded pasture of the Swiss Jura Mountains, where the soils are geogenically enriched in Cd (4.58 mg.kg(-1) on average (n = 36); maximal value: 16.3 mg.kg(-1)). ...

Elsevier Science Bv2015