Publication
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We present SPar-K (Signal Partitioning with K-means), a method to search for archetypical chromatin architectures by partitioning a set of genomic regions characterized by chromatin signal profiles around ChIP-seq peaks and other kinds of functional sites. This method efficiently deals with problems of data heterogeneity, limited misalignment of anchor points and unknown orientation of asymmetric patterns.
Alfio Quarteroni, Andrea Manzoni
Nikolaos Stergiopoulos, Sokratis Anagnostopoulos