Publication

SPar-K: a method to partition NGS signal data

Philipp Bucher, Romain Fernand Pietro Groux
2019
Journal Articles

Abstract

We present SPar-K (Signal Partitioning with K-means), a method to search for archetypical chromatin architectures by partitioning a set of genomic regions characterized by chromatin signal profiles around ChIP-seq peaks and other kinds of functional sites. This method efficiently deals with problems of data heterogeneity, limited misalignment of anchor points and unknown orientation of asymmetric patterns.

Official source

https://infoscience.epfl.ch/entities/publication/83080969-b9c5-4211-a451-e6ca0918ac7d

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SPar-K: a method to partition NGS signal data

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