Publications associées à Quantification of Strand Accessibility in Biostable DNA Origami with Single-Staple Resolution

Publications associées (30)

A method and system for optimizing design, implantation, and stimulation protocols of electrodes stimulating the nervous system

A method for optimizing at least one of a geometry, an implantation procedure, and/or stimulation protocol of one or more electrodes for an electrical stimulation of a target structure in a nervous system of a living being by a computer device, the method ...

2024

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Veronica Lily Ravano

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Collimation simulations for the FCC-ee

Milica Rakic, Tatiana Pieloni, Guillaume Clément Broggi, Giovanni Iadarola, Félix Simon Carlier

The collimation system of the Future Circular Collider, operating with leptons (FCC-ee), must protect not only the experiments against backgrounds, but also the machine itself from beam losses. With a 17.8 MJ stored energy of the electron and positron beam ...

Iop Publishing Ltd2024

Strain-based analysis on the influence of local undercut geometry on fatigue crack initiation life

Alain Nussbaumer

The local undercut defects at the weld toe provide a potential initiation site for fatigue cracks and significantly impact the structure's fatigue strength. The influence of continuous undercut depth on fatigue performance is widely studied, but the resear ...

2024

Ghost imaging using two SPAD array detectors: a parameter study towards the realization of a 3D quantum microscope

Edoardo Charbon, Claudio Bruschini, Paul Mos, Yang Lin

Quantum ghost imaging can be an important tool in making optical measurements. One of the most useful aspects of ghost imaging is the unique ability to correlate two sets of independently collected information. We aim to use the principles of ghost imaging ...

Spie-Int Soc Optical Engineering2024

FENNECS: a novel particle-in-cell code for simulating the formation of magnetized non-neutral plasmas trapped by electrodes of complex geometries

Guillaume Michel Le Bars, Stefano Alberti, Jean-Philippe Hogge, Joaquim Loizu Cisquella, Jérémy Genoud, Francesco Romano

This paper presents the new 2D electrostatic particle -in -cell code FENNECS developed to study the formation of magnetized non -neutral plasmas in geometries with azimuthal symmetry. This code has been developed in the domain of gyrotron electron gun desi ...

2024

Stress tolerance of lightweight glass-free PV modules for vehicle integration

Kléber Nicolet-dit-Félix, Christophe Ballif, Matthieu Despeisse, Aïcha Hessler-Wyser, Jacques Levrat, Antonin Faes, Gianluca Cattaneo, Umang Bhupatrai Desai, Fahradin Mujovi

Electric vehicles (EVs) currently dominate the sales in the automotive market. A big leap in this market can be made by developing a photovoltaic product that can be integrated to an EV, as it can boost the driving range of the EV while reducing the chargi ...

Edp Sciences S A2024

Geometric Learning: Leveraging differential geometry for learning and control

Bernardo Fichera

In this thesis, we concentrate on advancing high-level behavioral control policies for robotic systems within the framework of Dynamical Systems (DS). Throughout the course of this research, a unifying thread weaving through diverse fields emerges, and tha ...

EPFL2024

From low-rank retractions to dynamical low-rank approximation and back

Daniel Kressner, Axel Elie Joseph Séguin, Gianluca Ceruti

In algorithms for solving optimization problems constrained to a smooth manifold, retractions are a well-established tool to ensure that the iterates stay on the manifold. More recently, it has been demonstrated that retractions are a useful concept for ot ...

Springer2024

SC-TPTP: An Extension of the TPTP Derivation Format for Sequent-Based Calculus

Simon Guilloud

Motivated by the transfer of proofs between proof systems, and in particular from first order automated theorem provers (ATPs) to interactive theorem provers (ITPs), we specify an extension of the TPTP derivation text format to describe proofs in first-ord ...

2024

Modular segmentation, spatial analysis and visualization of volume electron microscopy datasets

Martin Weigert

Volume electron microscopy is the method of choice for the in situ interrogation of cellular ultrastructure at the nanometer scale, and with the increase in large raw image datasets generated, improving computational strategies for image segmentation and s ...

Nature Portfolio2024

Structural Insights into Electrophiles and Electrophilic Metabolites Sensing and Signaling: The Missing Information

Yimon Aye, Chloé Rogg

Native reactive electrophilic species (RES) are long-recognized regulators of pathophysiology; yet, knowledge surrounding how RES regulate context-specific biology remains limited. The latest technological advances in profiling and precision decoding of RE ...

WILEY-V C H VERLAG GMBH2023

Some Physical Implications Of Absolute Geometries In The Description Of Complex Systems Dynamics

Maria-Alexandra Paun

Some implications of absolute geometries in the description of complex systems dynamics, at various scale resolutions are highlighted. In such context, by means of an analytic geometry of 2 x 2 matrices, a generalization of the standard velocities space in ...

UNIV POLITEHNICA BUCHAREST, SCI BULL2023

Media Coverage of 3D Visual Tools Used in Urban Participatory Planning

Jens Ingensand, Thibaud Nicolas Chassin

The opportunities provided by adopting digitally-generated visual tools in urban participatory planning are compelling. These visual tools can promote interactions between authorities and citizens and among citizens. However, the urban participatory practi ...

IGI GLOBAL2023

Bayes Security: A Not So Average Metric

Carmela González Troncoso, Giovanni Cherubin

Security system designers favor worst-case security metrics, such as those derived from differential privacy (DP), due to the strong guarantees they provide. On the downside, these guarantees result in a high penalty on the system's performance. In this pa ...

IEEE2023

Numerical tools for burning plasmas

Laurent Villard, Jonathan Graves, Alberto Bottino, Ben McMillan, Emmanuel Lanti, Baruch Rofman

The software stack under development within a European coordinated effort on tools for burning plasma modelling is presented. The project is organised as a Task (TSVV Task 10) under the new E-TASC initiative (Litaudon et al 2022 Plasma Phys. Control. Fusio ...

IOP Publishing Ltd2023

Understanding Revision Behavior in Adaptive Writing Support Systems for Education

Tanja Christina Käser Jacober, Paola Mejia Domenzain, Thiemo Wambsganss, Luca Mouchel

Revision behavior in adaptive writing support systems is an important and relatively new area of research that can improve the design and effectiveness of these tools, and promote students' self-regulated learning (SRL). Understanding how these tools are u ...

Zenodo2023

T-5 configurations and hyperbolic systems

Riccardo Tione, Carl Johan Peter Johansson

In this paper, we study the rank-one convex hull of a differential inclusion associated to entropy solutions of a hyperbolic system of conservation laws. This was introduced in [B. Kirchheim, S. Muller and V. S(sic)ver & aacute;k, Studying Nonlinear PDE by ...

WORLD SCIENTIFIC PUBL CO PTE LTD2023

Digital Intervention for Collaborative and Human-Centered Activities in Design-Based Learning Scenarios

Denis Gillet, Isabelle Barbara Marie-Hélène Cardia, Jérémy Alain La Scala-Jayet

Training science and engineering students to become responsible citizens and professionals requires novel and creative pedagogical approaches, such as design thinking. This concept relies on processes and tools to develop creativity and problem-solving ski ...

IEEE2023

ROSMOSE: A Web-based Optimization Tool to Aid Decision-making for the Design and Operation of Industrial and Urban Energy Systems

François Maréchal, Daniel Alexander Florez Orrego, Meire Ellen Gorete Ribeiro Domingos, Cédric Terrier, Michel Lopez

Energy efficiency is crucial for the sustainable operation of all industrial and urban sectors. However, practicing engineers have seldom access to open-source tools that can readily evaluate and compare scenarios in terms of energy consumption, cost, and ...

2023