Publication

Optimization of the treatment of hydrocephalus by the non-invasive measurement of the intra-cranial pressure

Publications associées (32)

Radiation-tolerant Multichannel Dew Point Temperature Monitoring System for High Energy Physics Applications

The next generation of high-energy physics (HEP) detectors will predominantly be silicon-based. As pixel sensor technology gains momentum and the number of channels surpasses one billion (for a volume of approximately 20 m3) to achieve the high resolution ...

EPFL2023

Writing and Drawing Inventions: Patents and Technology in France and the United States (18th-19th centuries)

Jérôme Baudry

Description (through texts, images, models or samples) played a central role in the patent regimes that emerged in the eighteenth century, first in England, later in the United States and in France. Description ensured that the contract—protection in excha ...

2023

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

EPFL2023

Research data supporting 'Fiber pumps for wearable fluidic systems'

Herbert Shea, Vito Cacucciolo, Michael James Henry Smith

The dataset supporting 'Fiber pumps for wearable fluidic systems', published in Science in March 2023. In this work, we present a fluidic pump in the form of a flexible and stretchable tube. These tubes - or 'fiber pumps' - can generate significant fluidic ...

2023

CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Laura Desban, Ludovic Pierre Gustave Keiser

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) become activated during bacteri ...

CELL PRESS2023

Deep Learning Meets Sparse Regularization

Rahul Parhi

Deep learning (DL) has been wildly successful in practice, and most of the state-of-the-art machine learning methods are based on neural networks (NNs). Lacking, however, is a rigorous mathematical theory that adequately explains the amazing performance of ...

2023

lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

Alfio Quarteroni, Francesco Regazzoni, Marco Fedele, Stefano Pagani

Background: Simulating the cardiac function requires the numerical solution of multi-physics and multi-scale mathematical models. This underscores the need for streamlined, accurate, and high-performance computational tools. Despite the dedicated endeavors ...

BMC2023

The influence of the gas on the dynamics of cavitation bubbles

Davide Bernardo Preso

Cavitation bubbles, extensively investigated in fluid mechanics, present enduring challenges in hydraulic machinery, while holding considerable potential for practical applications in biomedicine and sonochemistry. Despite more than a century of research, ...

EPFL2023

Fiber pumps for wearable fluidic systems

Herbert Shea, Vito Cacucciolo, Michael James Henry Smith

Incorporating pressurized fluidic circuits into textiles can enable muscular support, thermoregulation, and haptic feedback in a convenient wearable form factor. However, conventional rigid pumps, with their associated noise and vibration, are unsuitable f ...

American Association for the Advancement of Science2023

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

Alfio Quarteroni, Luca Dede'

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory system. Our mod ...

Wiley2023

Quantification of the Phenomena Affecting Reflective Arterial Photoplethysmography

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas

Photoplethysmography (PPG) is a widely emerging method to assess vascular health in humans. The origins of the signal of reflective PPG on peripheral arteries have not been thoroughly investigated. We aimed to identify and quantify the optical and biomecha ...

MDPI2023

Dynamics of CLIMP-63 S-acylation control ER morphology

Kathryn Hess Bellwald, Béatrice Kunz, Graham Knott, Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Vassily Hatzimanikatis, Patrick Alain Sandoz, Robin Alexander Denhardt-Eriksson, Sylvia Ho, Luciano Andres Abriata, Catherine Maclachlan, Gard Spreemann

A key player in the formation of endoplasmic reticulum sheets is CLIMP-63, but mechanistic details remained elusive. Here authors combined cellular experiments and mathematical modelling to show that S-acylation of CLIMP-63 regulates its function by mediat ...

Nature Portfolio2023