Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

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Intermediate complexity atmospheric modeling in complex terrain: is it right?

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Dynamic downscaling of atmospheric forcing data to the hectometer resolution has shown increases in accuracy for landsurface models, but at great computational cost. Here we present a validation of a novel intermediate complexity atmospheric model, HICAR, ...

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Integrated Wireless Power, Data Communication, and Thermal Sensing System for Autonomous Multisite Brain Implants

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Implanted medical devices (IMDs) have been widely developed to support the monitoring and recording of biological data inside the body or brain. Wirelessly powered IMDs, a subset of implantable electronics, have been proposed to eliminate the limitations r ...

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Is There a Special Role for Ovarian Hormones in the Pathogenesis of Lobular Carcinoma?

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Lobular carcinoma represent the most common special histological subtype of breast cancer, with the majority classed as hormone receptor positive. Rates of invasive lobular carcinoma in postmenopausal women have been seen to increase globally, while other ...

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Reliable data-driven decision-making through optimal transport

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Decision-making permeates every aspect of human and societal development, from individuals' daily choices to the complex decisions made by communities and institutions. Central to effective decision-making is the discipline of optimization, which seeks th ...

EPFL2024

Computational drug development for membrane protein targets

Pierre Vogel, Henning Paul-Julius Stahlberg, Shuguang Yuan, Dongchun Ni, Babatunde Edukpe Ekundayo

The application of computational biology in drug development for membrane protein targets has experienced a boost from recent developments in deep learning-driven structure prediction, increased speed and resolution of structure elucidation, machine learni ...

2024

Generalization and Personalization of Machine Learning for Multimodal Mobile Sensing in Everyday Life

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A range of behavioral and contextual factors, including eating and drinking behavior, mood, social context, and other daily activities, can significantly impact an individual's quality of life and overall well-being. Therefore, inferring everyday life aspe ...

EPFL2024

Extensions of Peer Prediction Incentive Mechanisms

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As large, data-driven artificial intelligence models become ubiquitous, guaranteeing high data quality is imperative for constructing models. Crowdsourcing, community sensing, and data filtering have long been the standard approaches to guaranteeing or imp ...

EPFL2024

Search for the lepton flavour violating decays B0→e±μ∓ and B0s→e±μ∓ with LHCb Run 2 data

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A large variety of new physics models suggest that the rates for lepton flavour violating

b

-hadron decays may be much higher than predicted in the Standard Model, which leads to a high interest in the search for such decays. This thesis presents the se ...

EPFL2024

Turbulence in the Strongly Heterogeneous Near-Surface Boundary Layer over Patchy Snow

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The near-surface boundary layer above patchy snow cover in mountainous terrain is characterized by a highly complex interplay of various flows on multiple scales. In this study, we present data from a comprehensive field campaign that cover a period of 21 ...

2024

Discrete choice modeling in the era of big data

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The technological advancements of the past decades have allowed transforming an increasing part of our daily actions and decisions into storable data, leading to a radical change in the scale and scope of available data in relation to virtually any object ...

EPFL2024