In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

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Publications associées (30)

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Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

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Statistical physics of periodic biological processes

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Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet. Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuat ...

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Data and code associated with the paper 'Mode-Specific Coupling of Nanoparticle-on-Mirror Cavities with Cylindrical Vector Beams'

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Data and code associated with the following paper: V. Vento et al, Nano Lett. 2023 A thorough explanation of the experiment performed is available there. The name of each sub-folder and file in Maps_data_code.zip indicates the correspondin ...

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ALMOST SURE SCATTERING OF THE ENERGY-CRITICAL NLS IN d > 6

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We study the energy-critical nonlinear Schrodinger equation with randomised initial data in dimensions d > 6. We prove that the Cauchy problem is almost surely globally well-posed with scattering for randomised supercritical initial data in H-s(Rd) wheneve ...

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Data and Workflow to: Three-dimensional buoyant hydraulic fractures: finite volume release (Möri and Lecampion, (2023))

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This upload contains the relevant scripts, notebooks, and datasets to reproduce the numerically obtained results of the Journal article "Three-dimensional buoyant hydraulic fractures: finite volume release" by Möri and Lecampion, (2023). ...

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Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-based ...

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Data redundancy has been one of the most important problems in data-intensive applications such as data mining and machine learning. Removing data redundancy brings many benefits in efficient data updating, effective data storage, and error-free query proc ...

ELSEVIER2023

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Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...

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Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans

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The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...

American Association for the Advancement of Science2023

Imaging radial distribution functions of complex particles by relayed dynamic nuclear polarization

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Raw data and Matlab scripts from the publication at https://doi.org/10.1021/jacs.3c01279 All codes are provided free of charge and come with no warranty. Future use (original or modified) is required to cite: Zenedo data deposit at DOI 10.5281/zenodo. ...

Zenodo2023

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