Compliant vascular grafts and methods of use

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Publications associées (31)

Acute effects of transcatheter aortic valve replacement on the ventricular-aortic interaction

Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou, Vasiliki Bikia, Georgios Rovas

Transcatheter aortic valve replacement (TAVR) is increasingly used to treat severe aortic stenosis (AS) patients. However, little is known regarding the direct effect of TAVR on the ventricular-aortic interaction. In the present study, we aimed to investig ...

AMER PHYSIOLOGICAL SOC2020

Noninvasive estimation of aortic hemodynamics and cardiac contractility using machine learning

Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou, Vasiliki Bikia, Georgios Rovas

Cardiac and aortic characteristics are crucial for cardiovascular disease detection. However, noninvasive estimation of aortic hemodynamics and cardiac contractility is still challenging. This paper investigated the potential of estimating aortic systolic ...

Nature Research2020

Hemodynamics of ageing, ventricular-arterial coupling and noninvasive assessment of key hemodynamical and cardiac quantities

Stamatia Zoi Pagoulatou

Ageing is a natural process that affects both the anatomical and functional properties of the cardiovascular system and alters the coupling characteristics between the heart and the aorta. These alterations may predispose the cardiovascular system in the d ...

EPFL2020

Analysis of morphological and haemodynamical indexes in abdominal aortic aneurysms as preliminary indicators of intraluminal thrombus deposition

Alfio Quarteroni, Simone Deparis, Claudia Maria Colciago

In this paper we study the correlation between the Wall Shear Stress (WSS), a haemodynamical index derived from numerical simulations, and an new index MFA-ILT for the characterisation of intraluminal thrombus (ILT) in presence of abdominal aortic aneurysm ...

2020

The onset of cardiovascular disease in mice: an image-based, computational-experimental approach

Lydia Aslanidou

In a number of cardiovascular diseases, the paucity of longitudinal human data hinders our understanding of disease evolution and forestalls the discovery of new therapeutic strategies. We therefore heavily rely on animal models to elucidate the mechanisms ...

EPFL2019

Hemodynamics of Focal Versus Global Growth of Small Cerebral Aneurysms

Pierre Bouillot, Hasan Yilmaz

Background and PurposeHemodynamics play adriving role in the life cycle of brain aneurysms from initiation through growth until eventual rupture. The specific factors behind aneurysm growth, especially in small aneurysms, are not well elucidated. The goal ...

2019

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in Angiotensin-II-infused mice

Nikolaos Stergiopoulos, Patrick Segers, Bram Trachet, Lydia Aslanidou, Mauro Ferraro, Goran Lovric

Animal models of aortic aneurysm and dissection can enhance our limited understanding of the etiology of these lethal conditions particularly because early-stage longitudinal data are scant in humans. Yet, the pathogenesis of often-studied mouse models and ...

2019

On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging

Nikolaos Stergiopoulos, Bram Trachet, Stamatia Zoi Pagoulatou, Vasiliki Bikia

Mathematical models of the arterial tree constitute a valuable tool to investigate the hemodynamics of aging and pathology. Rendering such models as patient specific could allow for the assessment of central hemodynamic variables of clinical interest. Howe ...

AMER PHYSIOLOGICAL SOC2019

How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study

Mohamed Farhat, Philippe Reymond, Pierre Bouillot

BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, ...

American Society of Neuroradiology (ASNR)2019

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Nikolaos Stergiopoulos, Patrick Segers, Bram Trachet, Lydia Aslanidou, Mauro Ferraro, Goran Lovric

Synchrotron-based x-ray phase-contrast imaging allows for detailed 3D insight into the microstructure of soft tissue and is increasingly used to improve our understanding of mouse models of cardiovascular disease. Two techniques dominate the field: grating ...

2019

A systematic review and meta-analysis of the efficacy of aortic anastomotic devices

Nikolaos Stergiopoulos, Dimitrios Schizas

Objective: One of the factors contributing to complications related to open repair of the aorta is the construction of a hand-sewn anastomosis. Aortic anastomotic devices (AADs), such as the intraluminal ringed graft (IRG), and the anastomotic stenting tec ...

MOSBY-ELSEVIER2019

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