Publication

Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

Publications associées (31)

Microfluidic platforms for high-throughput mammalian cell printing, transfection, and dosage-dependent studies

With the advent of high-throughput and genome-wide screening initiatives, there is a need for improved methods for cell-based assays. Current approaches require expensive equipment, rely on large-scale culturing formats not suited for small or rare sample ...

EPFL2017

The Molecular Mechanism of Nanodroplet Stability

Yixing Chen, Sylvie Roke, Evangelia Zdrali, David Mark Wilkins, Halil Ibrahim Okur

Mixtures of nano- and microscopic oil droplets in water have recently been rediscovered as miniature reaction vessels in microfluidic environments and are important constituents of many environmental systems, food, personal care, and medical products. The ...

Amer Chemical Soc2017

Penciling a triboelectric nanogenerator on paper for autonomous power MEMS applications

Jürgen Brugger, Xiao Sheng Zhang

Triboelectric nanogenerator (TENG) has proven to be a robust power source to efficiently convert ambient mechanical energy into electricity. It experienced substantial growth in the past years owing to its appealing features that make it superior than othe ...

Elsevier Science Bv2017

High-throughput microfluidic platforms applied to immunoassay-based diagnostics and environmental monitoring

Francesca Volpetti

The research presented in this thesis is motivated by the aim to employ microfluidic devices for high-throughput analysis. Two applications, in particular, have been explored: diagnostics and environmental sensing. Miniaturization and multiplexing of labor ...

EPFL2017

Tailoring Surface Properties of Fiber Materials : Novel Opportunities in the Fabrication of Multi-scale Fiber-based Architectures

Dang Tùng Nguyen

Many surface properties of materials can be tailored by a proper physical patterning. Such patterned surfaces, commonly fabricated by wafer-based techniques, have been widely exploited for light trapping in advanced photovoltaic systems, for tailoring the ...

EPFL2017

Microfluidic staining technology and automated image processing for fast and accurate tissue-based diagnostics

Diego Gabriel Dupouy

The development of microfluidics has led to significant improvements in many areas of in vitro diagnostics. This thesis proposes the use of microfluidic device technology in the field of anatomic pathology, leading to faster and more accurate tissue-based ...

EPFL2016

Piégeage optique résonant et analyse du mouvement de nanoparticules piégées dans des cristaux photoniques à cavités creuses

Mario Lucien Henri Tonin

Optical trapping was used for decades in biotechnology for a broad range of applications. It can be used for remote manipulation, application of pico-Newton forces and even study DNA processes. Nevertheless, optical trapping setups can be cumbersome. In or ...

EPFL2016

Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer

Martinus Gijs, Déborah Heintze, Ata Tuna Ciftlik, Diego Gabriel Dupouy, Maryse Fiche

Chromogenic immunohistochemistry (IHC) is omnipresent in cancer diagnosis, but has also been criticized for its technical limit in quantifying the level of protein expression on tissue sections, thus potentially masking clinically relevant data. Shifting f ...

Nature Research2016

Merging microfluidics and micro-array concepts: from molecular to nematode-based bioassays

Matteo Cornaglia

Essential in biomedical research is the necessity of gathering statistically relevant data about large populations of specific biological entities, e.g. organisms, cells or molecules, while preserving detailed information about each single entity under in ...

EPFL2015

Ultra-rapid prototyping of flexible, multi-layered microfluidic devices via razor writing

Matthias Lütolf, Steffen Cosson, Nathalie Brandenberg

The fabrication of microfluidic devices is often still a time-consuming and costly process. Here we introduce a very simple and cheap microfabrication process based on "razor writing", also termed xurography, for the ultra-rapid prototyping of microfluidic ...

Royal Soc Chemistry2015

Microfluidic Scintillation Detectors for High Energy Physics

Pietro Maoddi

This thesis deals with the development and study of microfluidic scintillation detectors, a technology of recent introduction for the detection of high energy particles. Most of the interest for such devices comes from the use of a liquid scintillator, whi ...

EPFL2015