Publications associées à Sleep Apnea Detection using Features from the Respiration and the ECG recorded with Smart-Shirts

Finding information-rich electrocardiographic biomarkers to characterize atrial fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia; it will affect one in four adults worldwide in their lifetime. AF has serious consequences, including drastically increased risk of stroke. Catheter ablation surgery is an established treatmen ...

EPFL2023

Single-arm diagnostic electrocardiography with printed graphene on wearable textiles

Ata Jedari Golparvar

Stimulated by the COVID-19 outbreak, the global healthcare industry better acknowledges the necessity of innovating novel methods for remote healthcare monitoring and treating patients outside clinics. Here we report the development of two different types ...

ELSEVIER SCIENCE SA2023

Blunted Glucocorticoid Responsiveness to Stress Causes Behavioral and Biological Alterations That Lead to Posttraumatic Stress Disorder Vulnerability

Maria del Carmen Sandi Perez, Olivia Zanoletti, Jocelin Grosse, Sophie Elizabeth Walker, Marie-Isabelle Guillot de Suduiraut, Simone Astori, Silvia Monari

Background: Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid levels, sma ...

2023

Robust tunable acoustic impedance control on electroacoustic resonators for aircraft noise reduction

Maxime Volery

Air traffic noise emissions are responsible for a significant part of the overall environmental noise, especially in the vicinity of airports. Exposure to environmental noise is known to negatively impact health and to be associated with cardiovascular dis ...

EPFL2023

Genetic selection for low glucocorticoid responsiveness recapitulates PTSD-related phenotypes: a behavioral, neuroimaging and sleep-physiology study

Silvia Monari

Humans show inter-individual differences in vulnerability to develop post-traumatic stress disorder (PTSD) following exposure to trauma. Several critical biobehavioral features have been consistently described in PTSD patients, including blunted cortisol l ...

EPFL2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Putting Temperature into the Equation: Development and Validation of Algorithms to Distinguish Non-Wearing from Inactivity and Sleep in Wearable Sensors

Kamiar Aminian, Anisoara Ionescu, Sara Pagnamenta

Long-term monitoring of real-life physical activity (PA) using wearable devices is increasingly used in clinical and epidemiological studies. The quality of the recorded data is an important issue, as unreliable data may negatively affect the outcome measu ...

MDPI2022

Associations between urinary biomarkers of oxidative stress and biomarkers of tobacco smoke exposure in smokers

Dominique Grandjean, Florian Frédéric Vincent Breider, Nicolas Sambiagio

Oxidative stress can contribute to the development of diseases, and may originate from exposures to toxicants commonly found in air pollution and cigarette smoke such as polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Yet, as ...

Elsevier2022

Contactless Sleep Monitoring for Early Detection of Health Deteriorations in Community-Dwelling Older Adults: Exploratory Study

Philipp Buluschek, Daniel Gatica-Perez, Bruno Pais

Background: Population aging is posing multiple social and economic challenges to society. One such challenge is the social and economic burden related to increased health care expenditure caused by early institutionalizations. The use of modern pervasive ...

JMIR PUBLICATIONS, INC2021

ECG-Based Indices to Characterize Persistent Atrial Fibrillation Before and During Stepwise Catheter Ablation

Jean-Marc Vesin, Etienne Pruvot, Adrian Luca

Background: Consistently successful patient outcomes following catheter ablation (CA) for treatment of persistent atrial fibrillation (pers-AF) remain elusive. We propose an electrocardiogram (ECG) analysis designed to (1) refine selection of patients most ...

2021

Sleep disturbance-related depressive symptom and brain volume reduction in shift-working nurses

Chang-Hyun Park

Disturbed sleep is the most common effect of shift work. A large corpus of research indicates an association between sleep disturbance and depressive symptom in shift workers. In this study, we proposed the mediating role of grey matter (GM) structure in t ...

Nature Research2020

Automatic 12-lead ECG Classification Using a Convolutional Network Ensemble

Manoel Horta Ribeiro

The 12-lead electrocardiogram (ECG) is a major diagnostic test for cardiovascular diseases and enhanced automated analysis tools might lead to more reliable diagnosis and improved clinical practice. Deep neural networks are models composed of stacked trans ...

IEEE2020

Heart Rate Variability Triangular Index as a Predictor of Cardiovascular Mortality in Patients With Atrial Fibrillation

Vincent Schlageter, Jean-Marc Vesin

Background Impaired heart rate variability (HRV) is associated with increased mortality in sinus rhythm. However, HRV has not been systematically assessed in patients with atrial fibrillation (AF). We hypothesized that parameters of HRV may be predictive o ...

2020

Embedding Mobile Health Technology into the Nurses' Health Study 3 to Study Behavioral Risk Factors for Cancer

Christine Choirat

Background: Physical activity and sleep are behavioral risk factors for cancer that may be influenced by environmental exposures, including built and natural environments. However, many studies in this area are limited by residence-based exposure assessmen ...

2020

Monitoring of Cardiovascular and Neurological Diseases Using Wearable Devices

Dionisije Sopic

In this thesis, I focus on monitoring of patients suffering from cardiovascular and neurological diseases through the use of wearable devices. The main diseases considered in this thesis are atrial fibrillation (AF), myocardial infarction (MI), and epileps ...

EPFL2020

Evaluation of 1-Year in-Home Monitoring Technology by Home-Dwelling Older Adults, Family Caregivers, and Nurses

Philipp Buluschek, Daniel Gatica-Perez, Bruno Pais

Introduction:Population aging is increasing the needs and costs of healthcare. Both frailty and the chronic diseases affecting older people reduce their ability to live independently. However, most older people prefer to age in their own homes. New develop ...

2020

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Maxime Jan, Jake Yeung, Ioannis Xenarios

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Heart rate variability at bedtime predicts subsequent sleep features

Fiorenzo Artoni, Maria Paola Tramonti Fantozzi

Getting enough sleep during the night is important for preventing adverse short- and long-term health outcomes. The sympathetic-parasympathetic autonomic balance, characteristics of the pre-bed time resting period, correlates with sleep efficiency. We inve ...

IEEE2019

Tissue-specific circadian transcriptional regulation

Jake Yeung

Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-hour day, which requires extensive gene expression rhythms targeted to the right ...

EPFL2019

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Cyril Mikhail, Hasan Pezeshgi Modarres, Sha Li

Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral hypothalamus and play important roles in sleep, metabolism, reward, and motivation. Loss of HCRT (ligands or receptors) causes the sleep ...

National Academy of Sciences2019