Anne-Laure Mahul MellierExpertise
Cellular Biology: Cell culture of mammalian cell lines (U2OS, N2a, M17, SH-S5Y5, Cos, HeLa, HEK, MCF7), Astrocytic and neuronal primary cultures (hippocampus, cortex, striatum, midbrain) from P0 mouse or rat pups or from E16-E19 mice embryos, iPSC neuronal cultures (proliferation, passaging, differentiation in iNeurons or iDopaminergic neurons), Cellular transfection (DNA plasmid, siRNA, shRNA), Lentiviruses production and infection of neuronal primary cultures or mammalian cell lines, Samples pre
Luciano Andres AbriataEnseignement et PhD Cours Basic and advanced NMR - Level 1 A (EPFL) CH-601(x) Basic and advanced NMR - Level 2 (EPFL) CH-703 The goal is to give a sound theoretical and practical foundation in NMR for various applications in research. PhD students and post-docs who have followed the course successfully should be able to perform modern multi-dimensional NMR experiments independently. Integrative structural biology for Life sciences BIO-643 Recombinant protei
Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Alessandro BarducciEnseignement et PhD A co-dirigé les thèses EPFL de Salvatore Assenza, Duccio Malinverni
Esther AmstadEnseignement et PhD Doctorant·es actuel·les Reece Carolann Whatmore, Marc Elies Grädel, François Raphaël Rivat, Rocio Garcia Montero, Robin Michel Studer, Brian David Ridenour, Harsha Koganti, Zoubeir Saraw, Louisa Rinaldi, Greta Cocchi, Gaia Dupont A dirigé les thèses EPFL de Antoine Claude Jean Vian, Huachuan Du, Gianluca Etienne, Mathias Steinacher, Efe Armagan, Alvaro Lino Boris Charlet, Michael David Kessler, Aysu Ceren Okur, Matteo Hirsch, Chuen-Ru Li, Pauline Camille Charlotte Pradal, Gaia De Angel
Berend SmitEnseignement et PhD Doctorant·es actuel·les Anastasia Blokhina, Raluca-Ana Kessler, Seyed Amirmohammad Elahi, Juliette Veronique Schleicher, Yutao Li, Xin Jin, Sara Bassetta, Beatriz Bueno Mouriño A dirigé les thèses EPFL de Samantha Lynn Anderson, Daniele Ongari, Andrzej Gladysiak, Seyedmohamad Moosavi, Arunraj Chidambaram, Bardiya Valizadeh, Stavroula Kampouri, Fatmah Ebrahim, Fatma Pelin Uran, Andres Adolfo Ortega Guerrero, Kevin Maik Jablonka, Elias Moubarak, Sauradeep Majumdar, Miriam Jasmin Pougin,
Romain GuietExpertise
Development of BioImage Analysis workflows and algorithms to extract quantitative data from microscopy images.BioSample Preparation : in vitro cell, organoid, time-lapse, fixation, staining strategies, actin, mitochondria, fluorescent protein expressionBioImage Acquisition : Widefield, Confocal, Whole Slide Imaging, Super-resolution (SIM, STORM, STED), FRET, FRAP, FLIMBioImage Analysis: Colocalisation analysis, Deconvolution, Time-lapse , Whole Slide ImagingTools & Software: ImageJ/Fiji, QuPath, i
Elisa OricchioEnseignement et PhD Doctorant·es actuel·les Vamsi Krishna Polavarapu, Asli Ece Kasapoglu, Konstantina Georgakopoulou, Eleni Balli A dirigé les thèses EPFL de Maria Christine Donaldson, Elena Battistello, Daniel Pereira Duarte, Frédérica Schyrr, Ruxandra-Andreea Lambuta, Aaron Simone Petruzzella, Jixing Zhong, Justine Epiney Cours Cancer biology I BIO-471 Le cours couvre les mécanismes moléculaires du développement du cancer: le cycle cellulaire; la stabilité du génome; les oncogènes; les g
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