Engineering adjuvants for prophylactic and therapeutic subunit vaccines

Alexandre de Titta
2014
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Alexandre de Titta
2014
Theses

Source officielle

Publications associées (10)

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https://infoscience.epfl.ch/entities/publication/55583d5a-04d7-47b4-bafb-61d0d6fbd247

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Publications associées (10)

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The success of chimeric antigen receptor (CAR) T cell therapy in treating several hematopoietic malignancies has been difficult to replicate in solid tumors, in part because of T cell exhaustion and eventually dysfunction. To counter T cell dysfunction in ...

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Despite the remarkable success of immune checkpoint blockade (ICB) therapy, most cancer patients still do not respond. We now find that immunotherapy can induce stem-like properties in tumors. Using mouse models of breast cancer, we observe that cancer ste ...

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Background Activin-A, a transforming growth factor beta family member, is secreted by many cancer types and is often associated with poor disease prognosis. Previous studies have shown that Activin-A expression can promote cancer progression and reduce the ...

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