The ability of the brain to produce adaptive and dexterous movements relies on the seamless integration of sensory feedback into motor commands. Despite significant advances in motor neuroscience, critical gaps persist in understanding how proprioceptive a ...
Airborne bioparticles, including fungal spores, are of major concern for human and plant health, necessitating precise monitoring systems. While a European norm exists for manual volumetric monitoring, there's a growing interest in automated real-time meth ...
Background: The interpretation of lung sounds plays a crucial role in the appropriate diagnosis and management of pediatric asthma. Applying artificial intelligence (AI) to this task has the potential to better standardize assessment and may even improve i ...
Semantic segmentation with deep learning plays a crucial role in various fields, including civil engineering, particularly in tasks such as damage assessment and urban planning. This paper addresses the challenge of efficiently training deep learning model ...
Gradient-based learning in multi-layer neural networks displays a number of striking features. In particular, the decrease rate of empirical risk is non-monotone even after averaging over large batches. Long plateaus in which one observes barely any progre ...
Recently, remarkable progress has been made in the application of machine learning (ML) techniques (e.g., neural networks) to transformer fault diagnosis. However, the diagnostic processes employed by these techniques often suffer from a lack of interpreta ...
Steroid hormone receptors (HRs) are ligand-activated transcription factors that play a pivotal role in breast development and carcinogenesis. It is well established that estrogen receptor (ER) signaling is a major proliferative driver in estrogen receptor ...
This Workflow contains all the material necessary to reproduce the results of the QuPath analysis performed in the paper "Inhibition of CERS1 in aging skeletal muscle exacerbates age-related muscle impairments" Inside this workflow and dataset, you will f ...
In recent years, numerical simulations of hemodynamics have gained significant attention within the medical community, thanks to their ability of non-invasively estimating the blood flow conditions. However, high-fidelity simulations require extensive comp ...
Over the past years, implantable closed-loop neural interfaces have received increasing attention for their potential to enhance the understanding of the brain, treat neurological disorders, and provide unprecedented opportunities for individuals with para ...
Recent advancements in brain-machine interface (BMI) technology offer groundbreaking solutions for individuals with motor impairments, potentially extending to speech synthesis and handwriting assistance. However, current BMIs rely on cumbersome benchtop s ...
Traditional cell cultures have long been fundamental to biological research, offering an alternative to animal models burdened by ethical constraints and procedural intricacies, often lacking relevance to human physiology and disease. Moreover, their inabi ...
Modern neuroscience research is generating increasingly large datasets, from recording thousands of neurons over long timescales to behavioral recordings of animals spanning weeks, months, or even years. Despite a great variety in recording setups and expe ...
Machine learning (ML) enables artificial intelligent (AI) agents to learn autonomously from data obtained from their environment to perform tasks. Modern ML systems have proven to be extremely effective, reaching or even exceeding human intelligence.
Altho ...
Analysis of single-cell datasets generated from diverse organisms offers unprecedented opportunities to unravel fundamental evolutionary processes of conservation and diversification of cell types. However, interspecies genomic differences limit the joint ...
Explainable Artificial Intelligence (XAI) plays a crucial role in enabling human understanding and trust in deep learning systems, often defined as determining which features are most important to a model's prediction. As models get larger, more ubiquitous ...
Background: Cancer genome sequencing enables accurate classification of tumours and tumour subtypes. However, prediction performance is still limited using exome-only sequencing and for tumour types with low somatic mutation burden such as many paediatri ...
Author summaryIn recent years, the application of deep learning represented a breakthrough in the mass spectrometry (MS) field by improving the assignment of the correct sequence of amino acids from observable MS spectra without prior knowledge, also known ...
While the introduction of practical deep learning has driven progress across scientific fields, recent research highlighted that the requirement of deep learning for ever-increasing computational resources and data has potential negative impacts on the sci ...
Incomplete labels are common in multi-task learning for biomedical applications due to several practical difficulties, e.g., expensive annotation efforts by experts, limit of data collection, different sources of data. A naive approach to enable joint lear ...