Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike

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The atomic configuration of phases and their interfaces is fundamental to materials design and engineering. Here, we unveil a transition metal oxide interface, whose formation is driven by energetic influences─epitaxial tensile strain versus oxygen octahed ...

The oxidation behavior of stoichiometric Ti0.12Al0.21B0.67 coatings is investigated by scanning transmission electron microscopy (STEM) after oxidizing for 1, 4 and 8 h at 700 degrees C and at 800 and 900 degrees C. In the as deposited state, a similar to ...

Apoptosis controls cell fate, ensuring tissue homeostasis and promoting disease when dysregulated. The rate-limiting step in apoptosis is mitochondrial poration by the effector B cell lymphoma 2 (BCL-2) family proteins BAK and BAX, which are activated by i ...

Energy dispersive x-ray (EDX) spectrum imaging yields compositional information with a spatial resolution down to the atomic level. However, experimental limitations often produce extremely sparse and noisy EDX spectra. Under such conditions, every detecte ...

Living photovoltaics are microbial electrochemical devices that use whole cell–electrode interactions to convert solar energy to electricity. The bottleneck in these technologies is the limited electron transfer between the microbe and the electrode surfac ...

The density of a protein molecule is a key property within a variety of experimental techniques. We present a computational method for determining protein mass density that explicitly incorporates hydration effects. Our approach uses molecular dynamics sim ...

Recently, single-particle cryo-electron microscopy emerged as a technique capable of determining protein structures at near-atomic resolution and resolving protein dynamics with a temporal resolution ranging from second to milliseconds. This thesis describ ...

Whole-cell biophotovoltaic (BPV) devices leverage photoautotrophic microorganisms like cyanobacteria to convert sunlight and water into bioelectricity. They are capable of growing on sequestered carbon dioxide (CO2), eliminating the need to add exogenous o ...

Heterostructures consisting of SmNiO3 and NdNiO3 alternating layers with additional LaAlO3 spacer layers were grown and fully characterized by means of x-ray diffraction, atomic force microscopy, and scanning transmission electron microscopy. A change in t ...

Since the discovery of graphene in 2004, there has been rapid progress in research on two-dimensional (2D) material’s potential applications with significant impact. Efforts to bring 2D materials closer to industrial production, quality assessment, and sta ...

Transmembrane protein 16 F (TMEM16F) is a Ca2+-activated homodimer which functions as an ion channel and a phospholipid scramblase. Despite the availability of several TMEM16F cryogenic electron microscopy (cryo-EM) structures, the mechanism of activation ...

Proteins are the molecular machines of life, driving essential biological processes such as enzymatic catalysis, cellular signaling, and immune responses. The ability to design entirely new proteins with desired structures and functions has immense implica ...

Pacinian corpuscles are among the most sensitive mechanoreceptors found in vertebrates, and they are tuned to vibrations in the highest perceptible frequency range (100 to 2000 Hz). One of their anatomical hallmarks is the onion-like cell layers surroundin ...

Macrocycles offer an attractive format for drug development due to their good binding properties and potential to cross cell membranes. To efficiently identify macrocyclic ligands for new targets, methods for the synthesis and screening of large combinator ...

The initial and evolving microstructure during the tensile test of two Fe-17Mn-5Si-10Cr-4Ni shape memory alloys, with and without V, C and fabricated by laser powder bed fusion are investigated and compared via electron backscattered diffraction, transmiss ...

High throughput wide-field second harmonic imaging enables the label-free imaging of interfacial (< 3 nm thick) water, with a spatial resolution of similar to 370 nm using similar to 100 ms acquisition times per image. The obtained interfacial orientationa ...

With the advances in clean technologies, the role of fuel cells and batteries is becoming increasingly vital. Proton exchange membrane fuel cells are known to be the best candidates for low-temperature and portable operations, such as hydrogen cars. The ef ...

The process of protein aggregation, central to neurodegenerative diseases like Huntington’s, is challenging to study due to its unpredictable nature and relatively rapid kinetics. Understanding its biomechanics is crucial for unraveling its role in disease ...

The visualization and manipulation of proteins in live cells are critical for studying complex biological processes. Self-labeling proteins do so by enabling the specific and covalent attachment of synthetic probes, offering unprecedented flexibility in th ...

Intravenous (IV) iron-carbohydrate complexes are widely used nanoparticles (NPs) to treat iron deficiency anaemia, often associated with medical conditions such as chronic kidney disease, heart failure and various inflammatory conditions. Even though a ple ...

Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike

Chattez avec Graph Search

Engineering Symmetry Breaking Interfaces by Nanoscale Structural-Energetics in Orthorhombic Perovskite Thin Films

Passivating oxidation behavior of Ti0.12Al0.21B0.67 coatings investigated by scanning transmission electron microscopy and chemical environment dependent density functional theory simulations

Structural basis of BAK sequestration by MCL-1 in apoptosis

A Multiscale Bayesian Approach to Quantification and Denoising of Energy-dispersive X-ray Data

Polydopamine-coated photoautotrophic bacteria for improving extracellular electron transfer in living photovoltaics

The effect of hydration and dynamics on the mass density of single proteins

Microsecond Time-Resolved Cryo-Electron Microscopy

Bioanode engineering for living solar cells

Structural study of nickelate based heterostructures

Comprehensive benchmarking and user guide for the characterization of CVD-grown transition metal chalcogenides

Structural heterogeneity of the ion and lipid channel TMEM16F

Computational design of complex protein folds and soluble analogs of membrane proteins

Lamellar Schwann Cells in the Pacinian Corpuscle Potentiate Vibration Perception

Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation

Effect of precipitates on martensite formation and shape memory effect of FeMnSi-based shape memory alloys fabricated by laser powder bed fusion

Quantified interface chemistry and biophysics via water imaging

Advanced imaging of gas diffusion layers: A comparison between focused ion beam scanning electron microscopy and X-ray computed tomography

Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging

Exploiting Covalent Chemical Labeling with Self-Labeling Proteins

Iron-carbohydrate complexes treating iron anaemia: Understanding the nano-structure and interactions with proteins through orthogonal characterisation