Publications associées à Transcriptional Dynamics Of Neurorehabilitation In Spinal Cord Injury At Single-Nucleus Resolution

Publications associées (20)

Immersive VR for upper-extremity rehabilitation in patients with neurological disorders: a scoping review

Background Neurological disorders, such as stroke and chronic pain syndromes, profoundly impact independence and quality of life, especially when affecting upper extremity (UE) function. While conventional physical therapy has shown effectiveness in provid ...

BioMed Central2024

An immersive virtual reality system for ecological assessment of peripersonal and extrapersonal unilateral spatial neglect

Olaf Blanke, Andrea Serino, Roberta Ronchi, Ravi Tej Sai Giridhar Tadi

BackgroundUnilateral spatial neglect (USN) is a debilitating neuropsychological syndrome that often follows brain injury, in particular a stroke affecting the right hemisphere. In current clinical practice, the assessment of neglect is based on old-fashion ...

BioMed Central2023

NPTX1-related oculomotor apraxia: an intra-hemispheric disconnection disorder

Gabriel Girard, Philipp Johannes Koch

SPRINGER HEIDELBERG2022

Toward a joint automated assessment of cortical and paramagnetic rim lesions with 7T MRI

Meritxell Bach Cuadra, Francesco La Rosa

SAGE PUBLICATIONS LTD2022

Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis

Tobias Kober, Bénédicte Marie Maréchal

Background Early infratentorial and focal spinal cord lesions on magnetic resonance imaging (MRI) are associated with a higher risk of long-term disability in patients with multiple sclerosis (MS). The role of diffuse spinal cord lesions remains less under ...

BMC2022

Sleep And Shouts: The Intrinsically Aversive Nature Of Rough Sounds Is Preserved During Nrem Sleep

Dominique Grandjean

ELSEVIER2022

Pathological substrate of memory impairment in multiple system atrophy

Hilal Lashuel, Melek Firat Altay

Aims: Synaptic dysfunction in Parkinson's disease is caused by propagation of pathogenic alpha-synuclein between neurons. Previously, in multiple system atrophy (MSA), pathologically characterised by ectopic deposition of abnormal alpha-synuclein predomina ...

WILEY2022

Fingerprint of gait applied to Parkinson's disease

Enrico Amico

ELSEVIER2021

Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures

Tobias Kober, Bénédicte Marie Maréchal

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co morbidities in Parkinson's disease (PD) that affe ...

ELSEVIER2021

The perspectives of mapping and monitoring of the sense of self in neurosurgical patients

Olaf Blanke, Bruno Herbelin, Sophie Jacqueline Andrée Betka, Hyeongdong Park, Pavo Orepic, Sixto Luis Alcoba Banqueri

Surgical treatment of tumors, epileptic foci or of vascular origin, requires a detailed individual pre-surgical workup and intra-operative surveillance of brain functions to minimize the risk of post-surgical neurological deficits and decline of quality of ...

SPRINGER WIEN2021

Blood Flow to the Spleen is Altered in a Mouse Model of Spinal Muscular Atrophy

Bernard Schneider

Spinal muscular atrophy (SMA) is a neuromuscular disorder affecting young children. While pre-clinical models of SMA show small spleens, the same is not true in humans. Here, we show by doppler ultrasonography decreased splenic blood flow in Smn(2B/-) mice ...

2020

Cortical plasticity after hand prostheses use: Is the hypothesis of deafferented cortex "invasion" always true?

Silvestro Micera, Ivo Strauss, Stanisa Raspopovic, Giacomo Valle, Francesco Maria Petrini, Pablo Garcia del Valle, Edoardo D'Anna

Objective: To study motor cortex plasticity after a period of training with a new prototype of bidirectional hand prosthesis in three left trans-radial amputees, correlating these changes with the modification of Phantom Limb Pain (PLP) in the same period. ...

ELSEVIER IRELAND LTD2020

Advanced Neurotechnologies for the Restoration of Motor Function

Silvestro Micera, Friedhelm Christoph Hummel

Stroke is one of the leading causes of long-term disability. Advanced technological solutions ("neurotechnologies'') exploiting robotic systems and electrodes that stimulate the nervous system can increase the efficacy of stroke rehabilitation. Recent stud ...

2020

Establishment of a Therapeutic Ratio for Gamma Knife Radiosurgery of Trigeminal Neuralgia: The Critical Importance of Biologically Effective Dose Versus Physical Dose

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

OBJECTIVE: How variations of treatment time affect the safety and efficacy of Gamma Knife (GK) radiosurgery is a matter of considerable debate. With the relative simplicity of treatment planning for trigeminal neuralgia (TN), this question has been address ...

2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome

Daniela Maria Zöller, Maude Schneider

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic disease associated with an increased risk for schizophrenia and a specific cognitive profile. In this paper, we challenge the current view of spared verbal memory in 22q11.2DS by investigating v ...

2020

Autonomic Activation At Bedtime Predicts Subsequent Spindle Density

Fiorenzo Artoni

ELSEVIER2019

Optogenetic Dissection of the Basal Forebrain Neuromodulatory Control of Cortical Activation, Plasticity, and Cognition

Carl Petersen

The basal forebrain (BF) houses major ascending projections to the entire neocortex that have long been implicated in arousal, learning, and attention. The disruption of the BF has been linked with major neurological disorders, such as coma and Alzheimer's ...

Soc Neuroscience2015

The effect of arm weight support on upper limb muscle synergies during reaching movements

Silvestro Micera, Martina Coscia

Background: Compensating for the effect of gravity by providing arm-weight support (WS) is a technique often utilized in the rehabilitation of patients with neurological conditions such as stroke to facilitate the performance of arm movements during therap ...

BioMed Central2014

Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients

Patrick Aebischer, Nicole Déglon

Neuronal growth factors hold promise for providing therapeutic benefits in various neurological disorders. As a means of ensuring adequate central nervous system delivery of growth factors and minimizing significant adverse side effects associated with sys ...

1996