A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor

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Objective: Dysfunctional, unhealthy expansion of white adipose tissue due to excess dietary intake is a process at the root of obesity and Type 2 Diabetes development. The objective of this study is to contribute to a better understanding of the underlying ...

Multiple human pathogens establish chronic, sometimes life-long infections. Even if they are often latent, these infections can trigger some degree of local or systemic immune response, resulting in chronic low-grade inflammation. There remains an incomple ...

In this study, we map different types of channel geomorphic units in a sediment-starved, residual-flow reach before and after an artificial flood. Bedload particles of a previous sediment augmentation measure are tracked with passive integrated transponder ...

Motivated by the need for a better understanding of post-stroke recovery and new biomarkers to improve stroke patient stratification and outcomes, this thesis investigated structure-function coupling and its role in post-stroke recovery. Furthermore, in or ...

The presurgical window of opportunity trial (WOT) MIPRA provides evidence that neoadjuvant treatment with the prog-esterone receptor (PR) antagonist mifepristone (RU486) may benefit patients with estrogen receptor-positive (ER+) breast cancer characterized ...

Selective area epitaxy (SAE) provides the path for scalable fabrication of semiconductor nanostructures in a device-compatible configuration. In the current paradigm, SAE is understood as localized epitaxy, and is modelled by combining planar and self-asse ...

Humans can rapidly estimate the statistical properties of groups of stimuli, including their average and variability. But recent studies of so-called Feature Distribution Learning (FDL) have shown that observers can quickly learn even more complex aspects ...

By replacing part of Portland cement with so-called supplementary cementitious materials (SCMs) it is possible to reduce the CO2 footprint of the cement industry. These SCMs are commonly limestone, calcined clay, slag and fly ash. While doing so the early ...

Automated fact-checking is a needed technology to curtail the spread of online misinformation. One current framework for such solutions proposes to verify claims by retrieving supporting or refuting evidence from related textual sources. However, the reali ...

This paper analyzes efficiency and profitability in the Swiss banking sector over the period 1997–2019. We find strong evidence for scale economies: for most banks in the sample, efficiency and profitability increase with bank size. Using an instrumental v ...

The sedimentation process in an active suspension is the result of the competition between gravity and the autonomous motion of particles. We carry out simulations of run-and-tumble squirmers that move in a fluid medium, focusing on the dependence of the n ...

Motivated by the goal of designing interventions for softening polarized opinions on the Web, and building on results from psychology, we hypothesized that people would be moved more easily towards opposing opinions when the latter were voiced by a celebri ...

Exposure to daylight has much to offer and should be optimised to maximise its potential. In order to harvest its benefits, any visual discomfort from daylight should be anticipated and minimised. Hence, there is the need to predict discomfort from dayligh ...

Genotype imputation is a fundamental step in genomic data analysis, where missing variant genotypes are predicted using the existing genotypes of nearby "tag"variants. Although researchers can outsource genotype imputation, privacy concerns may prohibit ge ...

Perception depends not only on the current sensory input but also on the preceding history of stimuli. In serial dependence (SD), for example, the orientation of a Gabor patch is mistakenly reported as more similar to previous trials than it actually is. T ...

Whereas electron-phonon scattering relaxes the electron's momentum in metals, a perpetual exchange of momentum between phonons and electrons may conserve total momentum and lead to a coupled electron-phonon liquid. Such a phase of matter could be a platfor ...

A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor

Chattez avec Graph Search

GPS2-mediated regulation of the adipocyte secretome modulates adipose tissue remodeling at the onset of diet-induced obesity

The combined impact of persistent infections and human genetic variation on C-reactive protein levels

Influence of channel geomorphic units on bedload transport and river morphology during low‐magnitude bed‐forming floods coupled with sediment augmentation

Determining patterns of post-stroke motor recovery through longitudinal multimodal MRI: A step towards patient stratification

Targeting the Progesterone Receptor in Breast Cancer: Mind the Short Form!

Selective area epitaxy of GaAs: the unintuitive role of feature size and pitch

Feature distribution learning by passive exposure

Atomistic modeling of C-S-H: bulk and surface

Synthetic Disinformation Attacks on Automated Fact Verification Systems

Scale effects on efficiency and profitability in the Swiss banking sector

Hydrodynamic and geometric effects in the sedimentation of model run-and-tumble microswimmers

Interventions for Softening Can Lead to Hardening of Opinions: Evidence from a Randomized Controlled Trial

Is there a difference in how people from different socio-environmental contexts perceive discomfort due to glare from daylight?

Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation

Serial dependence does not originate from low-level visual processing

Evidence of a coupled electron-phonon liquid in NbGe2