Publications associées à Regiodivergent and Enantioselective Synthesis of Cyclic Sulfones via Ligand-Controlled Nickel-Catalyzed Hydroalkylation

Publications associées (19)

Novel Alkynylation Methods through the Combination of Hypervalent Iodine Reagents and Alkynyl-trifluoroborate Salts

The alkyne motif is a versatile functional group often encountered in organic chemistry. It can be involved in various transformations such as the alkyne-azide cycloaddition and has found widespread application in medicinal chemistry, chemical biology and ...

EPFL2024

A genetic optimization strategy with generality in asymmetric organocatalysis as a primary target

Anne-Clémence Corminboeuf, Rubén Laplaza Solanas, Simone Gallarati, Puck Elisabeth van Gerwen, Lucien Michel Gérard Brey

A catalyst possessing a broad substrate scope, in terms of both turnover and enantioselectivity, is sometimes called "general". Despite their great utility in asymmetric synthesis, truly general catalysts are difficult or expensive to discover via traditio ...

Royal Soc Chemistry2024

Correlating the Nature of Carbenium Ions in Zeolites to the Product Distribution in the Methanol-to-Olefins Process

Oliver Kröcher

The methanol-to-olefins (MTO) process on zeolite-based catalysts enables the production of olefins from green methanol. Selectivity control requires an understanding of the nature and evolution of hydrocarbon species that act as catalytically active center ...

AMER CHEMICAL SOC2024

New Applications of 1,3,2-Diazaphospholenes in Catalysis

Johannes Klett

The constant urge to construct new molecules in an economical and sustainable fashion led to the development of numerous metal-catalyzed transformations. Organocatalysts consisting of abundant and more sustainable elements offer an elegant solution to over ...

EPFL2024

Copper-Catalyzed Benzylic Functionalization of Lignin-Derived Monomers

Arthur Blumenstein, Xile Hu, Uttam Dhawa, Lara Lavrencic

Within the field of lignin biorefining, significant research effort has been dedicated to the advancement of catalytic methods for lignocellulose depolymerization. However, another key challenge in lignin valorization is the conversion of the obtained mono ...

WILEY-V C H VERLAG GMBH2023

Permanganate Reduction by Hydrogen Peroxide: Formation of Reactive Manganese Species and Superoxide and Enhanced Micropollutant Abatement

Urs von Gunten

Permanganate (MnO4-, Mn(VII)) is widely applied at the initial stage of water treatment to, e.g., abate taste and odor compounds, Mn(II) and Fe(II). However, its selectivity limits its application for micropollutant abatement. Hydrogen peroxide (H2O2), whi ...

AMER CHEMICAL SOC2021

Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis

Ana Garcia Herraiz, Nicolai Cramer, Benoît Daniel Bertrand Audic, Josep Más-Roselló, Aragorn Nathan Laverny

The creation of new chiral ligands capable of providing high stereocontrol in metal-catalyzed reactions is crucial in modern organic synthesis. The production of bioactive molecules as single enantiomers is increasingly required, and asymmetric catalysis w ...

Wiley-VCH Verlag GmbH2021

Hyper-Cross-Linked Polystyrene as a Stabilizing Medium for Small Metal Clusters

Lioubov Kiwi

Among different polymers nanostructured cross-linked aromatics have the greatest potential as catalytic supports due to their exceptional thermal and chemical stability and preservation of the active phase morphology. This work studies the ability of hyper ...

2021

Diamine Synthesis via the Nitrogen-Directed Azidation of sigma- and pi-C-C Bonds

Jérôme Waser, Mingming Wang

Diamines are essential building blocks for the synthesis of agrochemicals, drugs, and organic materials, yet their synthesis remains challenging, as both nitrogens need to be differentiated and diverse substitution patterns (1,2, 1,3, or 1,4) are required. ...

2021

Assessing Tetrel-Based Neutral Frustrated Lewis Pairs for Catalytic Hydrogenation

Shubhajit Das

Frustrated Lewis pair (FLP) chemistry has gained significant attention in the past decade as the main group hydrogenation catalysts. The majority of the reported FLP catalysts utilize either boron-containing Lewis acids (LAs) or alternatively isolobal and ...

AMER CHEMICAL SOC2021

Sustainable Hydrogenation of Nitroarenes to Anilines with Highly Active in-situ Generated Copper Nanoparticles

Berend Smit, Mounir Driss Mensi, Kyriakos Stylianou, Christopher Patrick Ireland, Ngoc Tú Nguyên, Fatma Pelin Uran

Metal nanoparticles (NPs) are usually stabilized by a capping agent, a surfactant, or a support material, to maintain their integrity. However, these strategies can impact their intrinsic catalytic activity. Here, we demonstrate that the in-situ formation ...

Wiley-VCH Verlag2020

Electron Beam Induced Copper Deposition from Carboxylate Precursors and the Study of Underlying Growth Mechanisms

Luisa Berger

The fabrication of defined and high-quality metal nanostructures is an ongoing topic of research. Direct-write deposition of copper nanostructures is of great value for many fields of research and industrial applications. Focused electron beam induced depo ...

EPFL2020

Mechanisms of the Heterogeneously Catalyzed Reaction of CO2 Hydrogenation on Transition Metal Surfaces

Kun Zhao

Renewable energy supply and energy storage in a closed materials cycle are the urgent global challenges of the 21st century. Carbon dioxide (CO2) hydrogenation over catalysts is a method to produce synthetic fuels from renewable energy in a CO2 neutral cyc ...

EPFL2020

Data-Driven Advancement of Homogeneous Nickel Catalyst Activity for Aryl Ether Cleavage

Anne-Clémence Corminboeuf, Matthew Wodrich, Benjamin André René Meyer, Manuel Cordova, Boodsarin Sawatlon

The increasing urgency to make chemical processes more environmentally friendly while continuing to derive the chemicals required for modern society from renewable resources requires the development of a forthcoming generation of synthetic processes and th ...

AMER CHEMICAL SOC2020

Metal-ligand bond strength determines the fate of organic ligands on the catalyst surface during the electrochemical CO(2)reduction reaction

Raffaella Buonsanti, Mounir Driss Mensi, Anna Loiudice, Pranit Srinivas Iyengar, James Richard Pankhurst

Colloidally synthesised nanocrystals (NCs) are increasingly utilised as catalysts to drive both thermal and electrocatalytic reactions. Their well-defined size and shape, controlled by organic ligands, are ideal to identify the parameters relevant to the a ...

2020

Organocatalysts in C-N Bond Forming Reactions of Amines with CO2

Martin Hulla

The thesis describes a simple approach for N-formylation of amines with CO2 and hydrosilane reducing agents, the use of organic salts as N-formylation catalysts, their physical properties required for high catalytic activity and their role in the catalytic ...

EPFL2019

Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents

Jérôme Waser, Guillaume Dominique Pisella, Julien Aymeric Borrel

We report the oxyalkynylation of thiiranes and thietanes using ethynylbenziodoxolone reagents (EBXs) to readily access functionalized building blocks bearing an alkynyl, a benzoate, and an iodide group. The reaction proceeds with high atom efficiency most ...

2019

Efficient Kinetic Resolution of Sulfur-Stereogenic Sulfoximines by Exploiting (CpRhIII)-Rh-X-Catalyzed C-H Functionalization

Marcus Brauns, Nicolai Cramer

Chiral sulfoximines with stereogenic sulfur atoms are promising motifs in drug discovery. We report an efficient method to access chiral sulfoximines through a C-H functionalization based kinetic resolution. A rhodium(III) complex equipped with a chiral Cp ...

Wiley-VCH Verlag GmbH2019

Ionic liquid containing electron-rich, porous polyphosphazene nanoreactors catalyze the transformation of CO2 to carbonates

Paul Joseph Dyson, Zhaofu Fei, Felix Daniel Bobbink, Zhangjun Huang, Haiyan Jia, Jorge Gustavo Uranga

We show that ionic liquids (ILs) interact with electron-rich, porous polyphosphazene (PPZ), to form hybrid PPZ-IL nanoreactors able to simultaneously capture and transform CO2 into carbonates. The PPZ nanospheres swell in organic solvents and effectively a ...

Royal Society of Chemistry2018