Monitoring Tyrosinase Expression in Non-metastatic and Metastatic Melanoma Tissues by Scanning Electrochemical Microscopy

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Super-resolution microscopy of defects in a two-dimensional material unveils the transport of single proton charges at solid/water interfaces. Aqueous proton transport at interfaces is ubiquitous and crucial for a number of fields, ranging from cellular tr ...

Non-invasive and semi-invasive bioimaging is of great interest for the rapid diagnosis and efficient as well as specific treatments of biological systems affecting human health, such as cancer tissue and biofilms. Electrochemical bioimaging is one of the d ...

Three-dimensional atomic force microscopy (3D-AFM) has resolved three-dimensional distributions of solvent molecules at solid-liquid interfaces at the subnanometer scale. This method is now being extended to the imaging of biopolymer assemblies such as chr ...

Among the prerequisites for the progress of single-molecule-based electronic devices are a better understanding of the electronic properties at the individual molecular level and the development of methods to tune the charge transport through molecular jun ...

This thesis investigates novel single-molecule luminescence phenomena at their inherent, sub-molecular length scale. The microscopic understanding of luminescence processes will be crucial for the continued improvement of organic optoelectronic and semicon ...

A noninvasive electrochemical melanoma detection approach based on using adhesive tapes for collecting and fixing cells from a suspicious skin area and transferring the cells into a scanning electrochemical microscope (SECM) is presented. The adhesive laye ...

Cutaneous melanoma is one of the most aggressive cancers characterized by a high plasticity, a propensity for metastasis, and drug resistance. Melanomas are composed of phenotypically diverse subpopulations of tumor cells with heterogeneous molecular profi ...

Solid cancers exhibit a dynamic balance between cell death and proliferation ensuring continuous tumour maintenance and growth(1,2). Increasing evidence links enhanced cancer cell apoptosis to paracrine activation of cells in the tumour microenvironment in ...

Many human cancers manifest the capability to circumvent attack by the adaptive immune system. In this work, we identified a component of immune evasion that involves frequent up-regulation of fragile X mental retardation protein (FMRP) in solid tumors. FM ...

In this work, a Mg(0001) single crystal is used as a novel template to grow 2D supramolecular nano-architectures. By using scanning tunnelling microscopy (STM) and high-resolution X-ray photoemission spectroscopy (HR-XPS), the formation of either a homo-mo ...

Liquid biopsies allow monitoring of cancer progression and detection of relapse, but reliable biomarkers in melanoma are lacking. Because secreted factors preferentially drain to lymphatic vessels before dilution in the blood, we hypothesized that lymph sh ...

The efficiency and peculiarities of processes such as surface adsorption or electron-to-photon energy conversion in organic and inorganic structures are determined by the dynamics at the scale of individual molecules, atoms and charges. The timescales of s ...

Nonbenzenoid carbocyclic rings are postulated to serve as important structural elements toward tuning the chemical and electronic properties of extended polycyclic aromatic hydrocarbons (PAHs, or namely nanographenes), necessitating a rational and atomical ...

The anti-Ly6G antibody is used to deplete Ly6G(pos) neutrophils and study their role in diverse pathologies. However, depletion is never absolute, as Ly6G(low) neutrophils resistant to depletion rapidly emerge. Studying the functionality of these residual ...

Scanning Near-field Optical Microscopy (SNOM) technique enables to overcome Abbe diffraction limit of far-field optics as well as to obtain simultaneously optical and topographical images. While the optical resolution of the method is limited by the apertu ...

The tumor microenvironment encompasses an intertwined ensemble of both transformed cancer cells and non-transformed host cells, which together establish a signaling network that regulates tumor progression. By conveying both homo- and heterotypic cell-to-c ...

Some preliminary results and experimental details of Near-field Scanning Optical Microscopy (NSOM) operation in liquids have been reported by us earlier(1-4). Here we present the first use of custom made polystyrene/poly (methyl methacrylate) (PMMA) optica ...

The paper deals with the preparation and investigation of a series of polymer dispersed liquid crystals (PDLCs) based on polysulfone matrix and an azomethine liquid crystal. The PDLC systems were prepared by thermal induced phase separation method. Their m ...

Nowadays, sharpened glass fiber - made probes attached to a quartz tuning fork (TF) and exploiting the shear force - based feedback are by far the most popular in the field of SNOM. These probes are expensive, very fragile and their fabrication is difficul ...

The invasive behavior of glioblastoma, the most aggressive primary brain tumor, is considered highly relevant for tumor recurrence. However, the invasion zone is difficult to visualize by Magnetic Resonance Imaging (MRI) and is protected by the blood brain ...

Monitoring Tyrosinase Expression in Non-metastatic and Metastatic Melanoma Tissues by Scanning Electrochemical Microscopy

Chattez avec Graph Search

Direct observation of water-mediated single-proton transport between hBN surface defects

Electrochemical imaging of metabolic activity in tissue and biofilms

Computed Three-Dimensional Atomic Force Microscopy Images of Biopolymers Using the Jarzynski Equality

Controlling Single Molecule Conductance by a Locally Induced Chemical Reaction on Individual Thiophene Units

Single molecule fluorescence and phosphorescence studies using a scanning tunneling microscope

Tape-Stripping Electrochemical Detection of Melanoma

Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-kappa B signaling pathway

Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

2-D assembly of supramolecular nanoarchitectures on Mg(0001)

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Dynamics of nanoscale systems probed by time-resolved STM-induced luminescence

Open-Shell Nonbenzenoid Nanographenes Containing Two Pairs of Pentagonal and Heptagonal Rings

Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy

Scanning near-field optical microscopy with new probes and feedback modes

Disentangling the complexity of tumor-derived extracellular vesicles

Chemically etched plastic optical fiber probe for near-field scanning optical microscopy in liquids

Polysulfone Dispersed Liquid Crystals As Promising Materials For Flexible Substrates Of Organic Light Emitting Diodes

Long-life plastic optical fiber probes for scanning near-field optical microscope

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice