Optimal Glass-Forming Solvent Brings Sublimation Dynamic Nuclear Polarization to 129Xe Hyperpolarization Biomedical Imaging Standards

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Publications associées (27)

Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

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A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo with the goal of improved diagnosis and perhaps therapy. Because of the complexity of biochemical pathways, tracer methods are required for detecting specific enzyme ...

2011

Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation

Arnaud Comment, Jean-Philippe Ansermet, Geoffrey Bodenhausen, François Lazeyras, Rolf Gruetter, Sami Jannin, Riddhiman Sarkar, Paul Romeo Vasos, Puneet Ahuja, Pascal Miéville, Jean-Noël Hyacinthe

A high throughput method was designed to produce hyperpolarized gases by combining lowtemperature dynamic nuclear polarization with a sublimation procedure. It is illustrated by applications to 129Xe nuclear magnetic resonance in xenon gas, leading to a si ...

American Physical Society2010

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In this thesis, the magnetic properties of self-assembled 3d and 4d metal nano-structures supported on surfaces have been investigated. The atomic coordination within the nano-structures was found to profoundly affect important quantities such as the magne ...

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Nuclear magnetic resonance (NMR) is used for a large array of applications, ranging from chemical characterization to oil drilling to medical imaging. In these fields NMR is used as an investigational tool, but new techniques and applications are continuou ...

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Nuclear Spin Relaxation Parameters of MRI Contrast Agents – Insight from Quantum Mechanical Calculations

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Nuclear magnetic relaxation in the presence of paramagnetic centres has gained increasing interest in recent years partly due to its importance for contrast agents in magnetic resonance imaging. Rational design of new more efficient agents is possible as a ...

Wiley-Blackwell2008

Design and performance of a DNP prepolarizer coupled to a rodent MRI scanner

Arnaud Comment, Jacques Van Der Klink, Rolf Gruetter, Sami Jannin, Fiodar Kurdzesau

For most of the last forty years, the techniques of Dynamic Nuclear Polarization (DNP) have been confined to particle-physics laboratories building polarized targets, but recently it has been shown that samples similar to a solid target can be transformed ...

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New strategies for highly efficient medical MRI contrast agents : Gd(III) poly(amino carboxylates) with fast water exchange and Gd(III) trapped in carbon cages

Sabrina Laus

During the last two decades, magnetic resonance imaging (MRI) has evolved into one of the most powerful techniques in medical diagnosis. Among the various medical diagnostic modalities, such as X-ray or ultra-sound imaging, MRI is the technique of choice e ...

EPFL2005

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