Publications associées à Crypt4GH: a file format standard enabling native access to encrypted data

Scalable and Privacy-Preserving Federated Principal Component Analysis

Jean-Pierre Hubaux, Jean-Philippe Léonard Bossuat, David Jules Froelicher, Joao André Gomes de Sá e Sousa, Juan Ramón Troncoso-Pastoriza, Apostolos Pyrgelis

Principal component analysis (PCA) is an essential algorithm for dimensionality reduction in many data science domains. We address the problem of performing a federated PCA on private data distributed among multiple data providers while ensuring data confi ...

IEEE COMPUTER SOC2023

Practical considerations of diffusion-weighted MRS with ultra-strong diffusion gradients

André Döring

IntroductionDiffusion-weighted magnetic resonance spectroscopy (DW-MRS) offers improved cellular specificity to microstructure-compared to water-based methods alone-but spatial resolution and SNR is severely reduced and slow-diffusing metabolites necessita ...

Frontiers Media Sa2023

A Practical Influence Approximation for Privacy-Preserving Data Filtering in Federated Learning

Boi Faltings, Panayiotis Danassis, Ljubomir Rokvic

Federated Learning by nature is susceptible to low-quality, corrupted, or even malicious data that can severely degrade the quality of the learned model. Traditional techniques for data valuation cannot be applied as the data is never revealed. We present ...

2023

Arbitrary Decisions are a Hidden Cost of Differentially Private Training

Bogdan Kulynych, Carmela González Troncoso

Mechanisms used in privacy-preserving machine learning often aim to guarantee differential privacy (DP) during model training. Practical DP-ensuring training methods use randomization when fitting model parameters to privacy-sensitive data (e.g., adding Ga ...

Assoc Computing Machinery2023

Interactive-time Exploration, Querying, and Analysis of Large High-dimensional Datasets

Sachin Basil John

In the current era of big data, aggregation queries on high-dimensional datasets are frequently utilized to uncover hidden patterns, trends, and correlations critical for effective business decision-making. Data cubes facilitate such queries by employing p ...

EPFL2023

Thwarting Malicious Adversaries in Homomorphic Encryption Pipelines

Sylvain Chatel

Homomorphic Encryption (HE) enables computations to be executed directly on encrypted data. As such, it is an auspicious solution for protecting the confidentiality of sensitive data without impeding its usability. However, HE does not provide any guarant ...

EPFL2023

Streamline RimNet: Tools for Automatic Classification of Paramagnetic Rim Lesions in MRI of Multiple Sclerosis

Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa, Maxence Charles F Wynen

This site provides two software tools related to "RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis" by Barquero et al. NeuroImage: Clinical (2020). People using in part or f ...

Zenodo2023

A robust walking detection algorithm using a single foot-worn inertial sensor: validation in real-life settings

Kamiar Aminian, Anisoara Ionescu, Gaëlle Prigent, Francesca Salis

Walking activity and gait parameters are considered among the most relevant mobility-related parameters. Currently, gait assessments have been mainly analyzed in laboratory or hospital settings, which only partially reflect usual performance (i.e., real wo ...

SPRINGER HEIDELBERG2023

Health data privacy through homomorphic encryption and distributed ledger computing: an ethical-legal qualitative expert assessment study

Marcello Ienca

Background: Increasingly, hospitals and research institutes are developing technical solutions for sharing patient data in a privacy preserving manner. Two of these technical solutions are homomorphic encryption and distributed ledger technology. Homomorph ...

BMC2022

Boosting Efficiency of External Pipelines by Blurring Application Boundaries

Anastasia Ailamaki, Periklis Chrysogelos, Anna Patricia Herlihy

Modern application development addresses increasingly specialized problems using domain-specific utilities, such as Optical Code Recognition and standalone statistical tools. The diversity of tooling, combined with the ever-growing volume of data, requires ...

2022

KRAB zinc-finger proteins and their transposable element targets: between antagonism and cooperation

Jonas Caspar De Tribolet-Hardy

There are 377 Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) in the human genome, making them the largest family of transcription factors. KZFPs are defined by a N-terminal KRAB domain and several zinc-finger domains arranged ...

EPFL2022

Towards mouse genetic-specific RNA-sequencing read mapping

Maxime Jan, Ioannis Xenarios

Genetic variations affect behavior and cause disease but understanding how these variants drive complex traits is still an open question. A common approach is to link the genetic variants to intermediate molecular phenotypes such as the transcriptome using ...

2022

Lightweight HI source finding for next generation radio surveys

Frédéric Courbin, Jean-Paul Richard Kneib, Aymeric Alexandre Galan, Austin Chandler Peel, Emma Elizabeth Tolley, Mark Thomas Sargent

Future deep HI surveys will be essential for understanding the nature of galaxies and the content of the Universe. However, the large volume of these data will require distributed and automated processing techniques. We introduce LiSA, a set of python modu ...

ELSEVIER2022

Disentangle genus microdiversity within a complex microbial community by using a multi-distance long-read binning method: example of Candidatus Accumulibacter

Aline Sondra Adler, Christof Holliger, Julien Maillard, Marco Pagni, Simon Marius Jean Poirier

Complete genomes can be recovered from metagenomes by assembling and binning DNA sequences into metagenome assembled genomes (MAGs). Yet, the presence of microdiversity can hamper the assembly and binning processes, possibly yielding chimeric, highly fragm ...

WILEY2022

Clouseau: Blockchain-based Data Integrity for HDFS Clusters

Ioannis Mytilinis

As the volume of produced data is exponentially increasing, companies tend to rely on distributed systems to meet the surging demand for storage capacity. With the business workflows becoming more and more complex, such systems often consist of or are acce ...

IEEE COMPUTER SOC2021

Analyzing and Protecting Communication Metadata

Ludovic Barman

Most communication systems (e.g., e-mails, instant messengers, VPNs) use encryption to prevent third parties from learning sensitive information. However, encrypted communications protect the contents but often leak metadata: the amount of data sent and th ...

EPFL2021

An Introduction to MPEG-G: The First Open ISO/IEC Standard for the Compression and Exchange of Genomic Sequencing Data

Marco Mattavelli

The development and progress of high-throughput sequencing technologies have transformed the sequencing of DNA from a scientific research challenge to practice. With the release of the latest generation of sequencing machines, the cost of sequencing a whol ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Software Support for Non-Volatile Memory (NVM) Programming

David Teksen Aksun

Non-Volatile Memory (NVM) is an emerging type of memory device that provides fast, byte-addressable, and high-capacity durable storage. NVM sits on the memory bus and allows durable data structures designs similar to the in-memory equivalent ones. Expensiv ...

EPFL2021

An Architecture for Load Balance in Computer Cluster Applications

Laurent Bindschaedler

Amid a data revolution that is transforming industries around the globe, computing systems have undergone a paradigm shift where many applications are scaled out to run on multiple computers in a computing cluster. As the storage and processing capabilitie ...

EPFL2020

Adaptive partitioning and indexing for in situ query processing

Anastasia Ailamaki, Manoussos Gavriil Athanassoulis, Ioannis Alagiannis, Matthaios Alexandros Olma, Manolis Karpathiotakis

The constant flux of data and queries alike has been pushing the boundaries of data analysis systems. The increasing size of raw data files has made data loading an expensive operation that delays the data-to-insight time. To alleviate the loading cost, in ...

SPRINGER2020