Implementation of the "loaded implant" model in the rat using a miniaturized setup - description of the method and first results

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Neuroprosthetics research has entered a stage in which animal models and proof-of-concept studies are translated into clinical applications, often combining implants with artificial intelligence techniques. This new phase raises the question of how clinica ...

Cartilage homeostasis, crucial for musculoskeletal function, is orchestrated by interconnected biophysical cues. In healthy cartilage, repetitive compressive loading not only elicits a range of mechanical stimuli but also induces a gradual transient temper ...

Electrical stimulation of the nervous system has emerged as a promising assistive technology in case of many injuries and illnesses across various parts of the nervous system. In particular, the invasive neuromodulation of the peripheral nervous system see ...

A method for optimizing at least one of a geometry, an implantation procedure, and/or stimulation protocol of one or more electrodes for an electrical stimulation of a target structure in a nervous system of a living being by a computer device, the method ...

The present invention relates to a neuromodulation/neurostimulation system (10) for the treatment of spasticity in a mammal, said system (10) comprising: - at least one control unit (12) configured and arranged to provide stimulation data, and - at least o ...

Objective. Peripheral nerve interfaces have the potential to restore sensory, motor, and visceral functions. In particular, intraneural interfaces allow targeting deep neural structures with high selectivity, even if their performance strongly depends upon ...

Treatment-resistant depression is a severe form of major depressive disorder and deep brain stimulation is currently an investigational treatment. The stimulation's therapeutic effect may be explained through the functional and structural connectivities be ...

The present invention relates to a combined neuromodulation and/or neurostimulation system (10) for mitigating locomotor deficits of/or neuronal disorders, especially Parkinson's disease, said system (10) comprising: - at least one Deep Brain Stimulation ( ...

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...

The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference stimulation (tTIS) is a novel, noninvasive technology that might overcome this limitation. The initial proof-of-co ...

The objective of this study was to determine the normative bone mineral density (BMD) of cortical and trabecular bone regions in the adult glenoid and its dependence on the subject's age and sex. We analyzed computed tomography (CT) scans of 441 shoulders ...

In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices able to record and stimulate electrical activity in the nervous system. These technologies improved the ability to diagnose and treat neural disorders. Neurotechnol ...

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

Transient electronics enabling devices to safely disappear in the environment can be applied not only in green electronics, but also in bioelectronic medicine. Neural implants able to degrade harmlessly inside the body eliminate the need for removal surger ...

Transcranial (electro)magnetic stimulation (TMS) is currently the method of choice to non-invasively induce neural activity in the human brain. A single transcranial stimulus induces a time-varying electric field in the brain that may evoke action potentia ...

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

Glenohumeral osteoarthritis is a degenerative shoulder joint disease, which causes the breakdown of articular cartilage and bone. People affected by this disease suffer from severe pain and eventually reduced mobility and poor life quality. This disease is ...

A mechanistic understanding of bone fracture is indispensable for developing improved fracture risk assessment in clinics. Since bone is a hierarchically structured material, gaining such knowledge requires analysis at multiple length scales. Here, the ten ...

The limitations and potential complications correlated with autogenous bone grafts have raised interest in the development of synthetic bone graft substitutes. ß-tricalcium phosphate (ß-TCP) is one of the most promising materials for synthetic bone graft s ...

Implementation of the "loaded implant" model in the rat using a miniaturized setup - description of the method and first results

Chattez avec Graph Search

Clinical trials for implantable neural prostheses: understanding the ethical and technical requirements

Synergetic Support of Cartilage Homeostasis via Coupled Thermal-Hydrostatic Pressure Stimuli

Biophysically accurate and machine learning-based surrogate models to optimize neuroprosthesis design and operation

A method and system for optimizing design, implantation, and stimulation protocols of electrodes stimulating the nervous system

System for control of spasticity

Combining biophysical models and machine learning to optimize implant geometry and stimulation protocol for intraneural electrodes

Linking connectivity of deep brain stimulation of nucleus accumbens area with clinical depression improvements: a retrospective longitudinal case series

Neuromodulation/neurostimulation system for mitigating locomotor deficits of parkinson's disease, spinal cord injury (sci), stroke and/or other neurological disorders

Sensory-Motor Neurostimulation to Enhance Exosuit Performance

Noninvasive theta-burst stimulation of the human striatum enhances striatal activity and motor skill learning

Age- and sex-specific normative values of bone mineral density in the adult glenoid

Clinical neuroscience and neurotechnology: An amazing symbiosis

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Development of a Transient Neural Interface for Minimally Invasive Recording and Stimulation

Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Overcorrected Implants for Total Shoulder Arthroplasty

Microtensile failure mechanisms in lamellar bone: Influence of fibrillar orientation, specimen size and hydration

Atomistic simulation and electron microscopy to characterize grain boundaries in doped beta-tricalcium phosphate ceramics