Inner ear cellular imaging through scattering bone

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The formation of elemental trigonal tellurium (t-Te) on tellurite glass surfaces exposed to femtosecond laser pulses is discussed. Specifically, the underlying elemental crystallization phenomenon is investigated by altering laser parameters in common tell ...

Second harmonic generation microscopy is used to image interfaces or non-centrosymmetric structures and molecules. Two-photon fluorescence microscopy can image molecules within cells without using markers. Thus those technics have lead to advances in our u ...

Viral delivery of exogenous coding sequences into the inner ear has the potential for therapeutic benefit for patients suffering genetic or acquired hearing loss. To devise improved strategies for viral delivery, we investigated two injection techniques, r ...

A distributed sensor for multi-event alarm triggering is demonstrated by measuring the loss change induced by the liquefaction of pressured CO2 trapped along a side air-hole fiber. ...

Inspired by the prominent theory suggesting that auditory-verbal hallucinations (AVH) - the sensation of hearing voices without present speakers - arise as misattribution of inner speech towards external agents, my thesis revolved around self-voice percept ...

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

Significance: Despite recent developments in microscopy, temporal aliasing can arise when imaging dynamic samples. Modern sampling frameworks, such as generalized sampling, mitigate aliasing but require measurement of temporally overlapping and potentially ...

A remote microphone (RM) system can be used in combination with wearable binaural communication devices, such as hearing aids (HAs), to improve speech intelligibility. Typically, a speaker is equipped with a body-worn microphone which enables to pick up th ...

We propose GoldFinger, a new compact and fast-to-compute binary representation of datasets to approximate Jaccard’s index. We illustrate the effectiveness of GoldFinger on the emblematic big data problem of K-Nearest-Neighbor (KNN) graph construction and s ...

The ability to switch ferroics (ferro-, ferri-, antiferromagnets, ferroelectrics, multiferroics) between two stable bit states is one of the keystones of modern data storage technology. Due to many new ideas, originating from fundamental research during th ...

We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...

Recently, flexible and soft bioelectronic interfaces have been proposed as a solution to improve existing neural interfaces that currently present mechanical mismatch with the soft tissue. These are devices fabricated with thin polymeric or elastomeric bac ...

As of today, the extension of the human visual capabilities to machines remains both a cornerstone and an open challenge in the attempt to develop intelligent systems. On the one hand, the development of more and more sophisticated imaging devices, capable ...

The estimation of the orientation of an object, and a human head in particular, can be defined by the Euler angles: the yaw, pitch and roll. The robust and drift-free estimation of those angles is usually achieved with the data from several sensors such as ...

A light pulse source (100), being adapted for generating repetitive optical pulses (1), comprises a continuous wave cw laser device (10) being arranged for providing cw laser light (2), an optical waveguide (20) being optically coupled with the cw laser de ...

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

Imaging the inner ear microanatomy is of great importance for the assessment of the state of the cells responsible for sound detection. Hearing disorders are mainly due to a malfunction of the cochlea, the bone containing the cells inside the inner ear. Un ...

Inner ear cellular imaging through scattering bone

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Formation Mechanism of Elemental Te Produced in Tellurite Glass Systems by Femtosecond Laser Irradiation

A tunable femtosecond fiber laser source for multiphoton emission microscopy

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B

Distributed Alarm System Based on OTDR Interrogation of Side Air-Hole Fibers

Dissecting self-voice perception: From bone conduction to robotically-induced self-other voice misattribution in healthy listeners

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

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Graph-based regularization of inverse problems in imaging

Human Head Yaw Estimation based on Two 3-axis Accelerometers

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Biomedical optical techniques for intracochlear cellular imaging