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Friedhelm Christoph Hummel

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Publications associées (88)

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Detecting Compensatory Motions and Providing Informative Feedback During a Tangible Robot Assisted Game for Post-Stroke Rehabilitation

Pierre Dillenbourg, Friedhelm Christoph Hummel, Barbara Bruno, Maximilian Jonas Wessel, Ayberk Özgür, Arzu Güneysu Özgür, Hala Khodr

Gamified rehabilitation tackles the problem of keeping patients engaged in, and motivated to do physical rehabilitation to improve its efficacy. However, with respect to standard rehabilitation, patients are freer to move about and may compensate their mot ...

IEEE2021

Mini-review: Transcranial Alternating Current Stimulation and the Cerebellum

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Laurijn Rianne Draaisma

Oscillatory activity in the cerebellum and linked networks is an important aspect of neuronal processing and functional implementation of behavior. So far, it was challenging to quantify and study cerebellar oscillatory signatures in human neuroscience due ...

2023

Precision non-invasive brain stimulation: an in silico pipeline for personalized control of brain dynamics

Friedhelm Christoph Hummel, Elena Beanato

Objective. Non-invasive brain stimulation (NIBS) offers therapeutic benefits for various brain disorders. Personalization may enhance these benefits by optimizing stimulation parameters for individual subjects. Approach. We present a computational pipeline ...

2025

EPFL-Smart-Kitchen-30 Collected data

Silvestro Micera, Friedhelm Christoph Hummel, Solaiman Shokur, Alexander Mathis, Mahdi Hamidi Rad, Haozhe Qi, Franklin Leong, Andy Bonnetto, Matea Tashkovska

Understanding behavior requires datasets that capture humans while carrying out complex tasks. The kitchen is an excellent environment for assessing human motor and cognitive function, as many complex actions are naturally exhibited in kitchens from choppi ...

Zenodo2025

Pathway-dependent Brain Stimulation Responses Indicate Motion Processing Integrity After Stroke

Nicola Rachel Adele Ramdass, Friedhelm Christoph Hummel, Elena Beanato, Estelle Emeline Raffin, Lisa Aïcha Mireille Julie Fleury, Fabienne Windel, Michele Bevilacqua, Pauline Menoud, Sarah Bernardina Zandvliet, Julie Loréline Valériane Hervé

Homonymous hemianopia (HH), a common visual impairment resulting from occipital lobe lesions, affects a significant number of stroke survivors. Intensive perceptual training can foster recovery, possibly by enhancing surviving visual pathways. This study e ...

OXFORD UNIV PRESS2025

Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity

Friedhelm Christoph Hummel, Estelle Emeline Raffin, Sarah Bernardina Zandvliet, Roberto Felipe Salamanca Giron

Visual motion discrimination involves reciprocal interactions in the alpha band between the primary visual cortex (V1) and mediotemporal areas (V5/MT). We investigated whether modulating alpha phase synchronization using individualized multisite transcrani ...

2021

Disconnectomics of the Rich Club Impacts Motor Recovery After Stroke

Friedhelm Christoph Hummel, Gabriel Girard, Chang-Hyun Park, Elena Beanato, Philip Egger, Philipp Johannes Koch, Giorgia Giulia Evangelista

BACKGROUND AND PURPOSE: Structural brain networks possess a few hubs, which are not only highly connected to the rest of the brain but are also highly connected to each other. These hubs, which form a rich-club, play a central role in global brain organiza ...

2021

Computer vision-based algorithm to sUppoRt coRrect electrode placemeNT (CURRENT) for home-based electric non-invasive brain stimulation

Jean-Philippe Thiran, Friedhelm Christoph Hummel, Takuya Morishita, Roser Vinals Terres, Rémy Marc M Gardier, Fabienne Windel

Objective: Home-based non-invasive brain stimulation (NIBS) has been suggested as an adjunct treatment strategy for neuro-psychiatric disorders. There are currently no available solutions to direct and monitor correct placement of the stimulation electrode ...

2023

Causal role of the inferolateral prefrontal cortex in balancing goal-directed and habitual control of behavior

Friedhelm Christoph Hummel

Successful adaptation to complex environments depends on the balance of at least two systems: a flexible but slow goal-directed system encoding action-outcome associations and an efficient but rigid habitual system linking responses to preceding stimuli. R ...

Nature Research2018

Preserved Corticospinal Tract Revealed by Acute Perfusion Imaging Relates to Better Outcome After Thrombectomy in Stroke

Friedhelm Christoph Hummel, Philipp Johannes Koch

BACKGROUND:The indication for mechanical thrombectomy (MT) in stroke patients with large vessel occlusion has been constantly expanded over the past years. Despite remarkable treatment effects at the group level in clinical trials, many patients remain sev ...

Lippincott Williams & Wilkins2023

Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Takuya Morishita, Chang-Hyun Park, Philipp Johannes Koch, Pablo Maceira Elvira, Manon Chloé Durand-Ruel, Laurijn Rianne Draaisma

The development of novel strategies to augment motor training success is of great interest for healthy persons and neurological patients. A promising approach is the combination of training with transcranial electric stimulation. However, limited reproduci ...

NATURE RESEARCH2020

A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of transcranial direct current stimulation to the motor cortex after stroke (NETS): study protocol

Friedhelm Christoph Hummel

Introduction The WHO estimates that each year 5 million people are left permanently disabled after stroke. Adjuvant treatments to promote the effects of rehabilitation are urgently needed. Cortical excitability and neuroplasticity can be enhanced by non-in ...

SPRINGERNATURE2022

The importance of neuronal networks for motor rehabilitation after a stroke

Friedhelm Christoph Hummel

Every year in Europe 1.5 million patients suffer a new stroke. Despite the further developments in acute therapy with nationwide stroke units, thrombolysis, thrombectomy and post-acute neurorehabilitation, only a small proportion of patients recover to a s ...

Springer Verlag2017

Robotic-Aided Training and Assessment of Upper Limb Muscle Coordination Following Stroke

Friedhelm Christoph Hummel, Takuya Morishita, Claudia Bigoni

Technology-aided interventions and assessments are at the base of personalized motor rehabilitation after stroke. In the AVANCER trial, the effects of a novel personalized neurotech intervention were assessed by using an instrumented Fugl-Meyer (FM) evalua ...

Springer Nature Switzerland2025

Dissecting motor skill acquisition: Spatial coordinates take precedence

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Takuya Morishita, Traian Popa, Pablo Maceira Elvira, Anne-Christine Schmid

Practicing a previously unknown motor sequence often leads to the consolidation of motor chunks, which enable its accurate execution at increasing speeds. Recent imaging studies suggest the function of these structures to be more related to the encoding, s ...

AMER ASSOC ADVANCEMENT SCIENCE2022

Noninvasive modulation of the hippocampal-entorhinal complex during spatial navigation in humans

Olaf Blanke, Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Elena Beanato, Traian Popa, Pierre Theopistos Vassiliadis, Baptiste Gauthier, Emanuela De Falco, Fabienne Windel, Pauline Menoud, Hyukjun Moon, Esra Neufeld

Because of the depth of the hippocampal-entorhinal complex (HC-EC) in the brain, understanding of its role in spatial navigation via neuromodulation was limited in humans. Here, we aimed to better elucidate this relationship in healthy volunteers, using tr ...

American Association for the Advancement of Science (AAAS)2024

Transcranial Temporal Interference Stimulation (ttis): Pioneering Non-invasive Deep Brain Neuromodulation for Movement Disorders and Beyond

Friedhelm Christoph Hummel

WILEY2025

Multifocal stimulation of the cerebro-cerebellar loop during the acquisition of a novel motor skill

Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Chang-Hyun Park, Elena Beanato, Philipp Johannes Koch

Transcranial direct current stimulation (tDCS)-based interventions for augmenting motor learning are gaining interest in systems neuroscience and clinical research. Current approaches focus largely on monofocal motorcortical stimulation. Innovative stimula ...

Nature Research2021

Resting-State Cortico-Cerebellar Connectivity Correlates with Post-Stroke Motor Recovery - A Prospective Functional MRI Study

Friedhelm Christoph Hummel, Elena Beanato

Cerebellar functional and structural connectivity are likely related to motor function after stroke. Less is known about motor recovery, which is defined as a gain of function between two time points, and about the involvement of the cerebellum. Fifteen pa ...

2025

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment

Friedhelm Christoph Hummel, Traian Popa, Pablo Maceira Elvira, Anne-Christine Schmid

Stroke is one of the main causes of long-term disability worldwide, placing a large burden on individuals and society. Rehabilitation after stroke consists of an iterative process involving assessments and specialized training, aspects often constrained by ...

BioMed Central2019