Alexandre Louis André Persat

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Publications associées (26)

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Cellular advective-diffusion drives the emergence of bacterial surface colonization patterns and heterogeneity

Alexandre Louis André Persat, Tamara Rossy

Microorganisms navigate and divide on surfaces to form multicellular structures called biofilms, the most widespread survival strategy found in the bacterial world. One common assumption is that cellular components guide the spatial architecture and arrang ...

Nature Research2019

An Ohmic model for electrokinetic flows of binary asymmetric electrolytes

Alexandre Louis André Persat

The transport of electrolytes in electric fields is a ubiquitous phenomenon commonly harnessed in microfluidics. A classic leaky dielectric model for flow generated by electric fields accurately predicts electrohydrodynamic transport phenomenon but is vali ...

Elsevier Science London2016

Fluid flow structures gut microbiota biofilm communities by distributing public goods

Tom Ian Battin, Alexandre Louis André Persat, Jeremy Pak Hei Wong

Bacterial gut commensals experience a biologically and physically complex mucosal environment. While many chemical factors mediate the composition and structure of these microbial communities, less is known about the role of mechanics. Here, we demonstrate ...

National Academy of Sciences2023

Mechanotaxis directs Pseudomonas aeruginosa twitching motility

Alexandre Louis André Persat, Lorenzo Anton-Louis Talà, Xavier Jean-Yves Pierrat, Jose Negrete Jr, Zaïnebe Dhirani, Marco Julian Kühn

The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellu-lar filaments called type IV pili (T4P). Single cells twitch by sequen-tial T4P extension, attachment, and retraction. How single ...

National Academy of Sciences2021

Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions

John McKinney, Alexandre Louis André Persat

In vitro models mimicking in-patient conditions have the potential to yield exciting opportunities for antibiotic research and revitalize future antibiotic discovery and development. ...

Nature Portfolio2024

Bacterial Mechanosensing with Type IV Pili

Alexandre Louis André Persat, Xavier Jean-Yves Pierrat, Lorenzo Anton-Louis Talà

CELL PRESS2018