Publications de Mahmut Selman Sakar

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Classic microsurgical techniques, such as those used in the early 1900s by Mangold and Spemann, have been instrumental in advancing our understanding of embryonic development. However, these techniques are highly specialized, leading to issues of inter-ope ...

The comprehension of physical wave phenomena is imperative for students in the fields of engineering and basic sciences. Laboratory experiments that involve generation of acoustic waves can be used to explain advanced nonlinear wave phenomena. Acoustic lev ...

One of the grand challenges in interventional cardiology and neuroradiology is to minimize the operation time and risk of damage during catheterization. These two factors drastically increase if the target location resides in small and tortuous vessels. Fl ...

A flow directed device adapted to be guided by a fuid, such as blood, flow within a tubular structure such as a blood vessel is disclosed, said device comprising a proximal end (100), a distal end (101) and an elongated body (102) in between defining a lon ...

Microbubbles excited by acoustic fields inside water oscillate, and generate acoustic radiation forces and drag-induced acoustic streaming. These forces can be harnessed in various biomedical applications such as targeted drug delivery and on-chip biomanip ...

This paper presents the design, fabrication, and operation of compound micromachines powered by acoustic streaming. The machine components were directly incorporated around pillars serving as shafts without further assembly steps using a single-step in sit ...

An alternative intracranial aneurysm embolic agent is emerging in the form of hydrogels due to their ability to be injected in liquid phase and solidify in situ. Hydrogels have the ability to fill an aneurysm sac more completely compared to solid implants ...

Miniaturized three-dimensional (3D) cell culture systems, in particular organoids and spheroids, hold great potential for studying morphogenesis, disease modeling, and drug discovery. However, sub-cellular resolution 3D imaging of these biological samples ...

Microsurgical manipulations are key experimental techniques in life science research, particularly in embryology. These techniques are most often performed manually by highly skilled scientists, posing limitations on speed, precision, and reproducibility. ...

Engineered fibrous tissues consisting of cells encapsulated within collagen gels are widely used three-dimensional (3D) in vitro models of morphogenesis and wound healing. While cell-mediated matrix remodeling that occurs within these scaffolds has been ex ...

This paper presents the design, fabrication, and operation of a soft robotic compression device that is remotely powered by laser illumination. We combined the rapid and wireless response of hybrid nanomaterials with state-of-the-art microengineering techn ...

Tissue morphogenesis and regeneration are essentially mechanical processes that involve coordination of cellular forces, production and structural remodeling of extracellular matrix (ECM), and cell migration. Discovering the principles of cell–ECM interact ...

Shape shifting soft microrobots are generated from self-folding hydrogel bilayer structures. The folding conditions are analyzed to develop an optimal strategy for producing desired three-dimensional shapes. We present two different methods for programming ...

Mahmut Selman Sakar

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Deconstructing body axis morphogenesis in zebrafish embryos using robot-assisted tissue micromanipulation

A graduate laboratory experiment to study the dynamics of an acoustically levitated particle

Locomotion of Sensor‐Integrated Soft Robotic Devices Inside Sub‐Millimeter Arteries with Impaired Flow Conditions

Ultraflexible flow directed device and system

Dynamics of entrapped microbubbles with multiple openings

Compound micromachines powered by acoustic streaming

Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms

An acoustic levitation platform for high-content histological analysis of 3D tissue culture

A Robotic Surgery Platform for Automated Tissue Micromanipulation in Zebrafish Embryos

Surface and bulk stresses drive morphological changes in fibrous microtissues

Investigating Tissue Mechanics in vitro Using Untethered Soft Robotic Microdevices

A model for 3D deformation and reconstruction of contractile microtissues

Magnetic microrobots with addressable shape control

On-Board Mechanical Control Systems for Untethered Microrobots

Kinematic and dynamic analysis of the mosquito larvae gait

Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs

Precise tactile stimulation of worker ants by a robotic manipulator reveals that individual responses are density‐ and context‐dependent

A model for mechanosensitive cell migration in dynamically morphing soft tissues

Actuated 3D microgels for single cell mechanobiology (vol 22, pg 1962, 2022)

Engineering Control over 3D Morphogenesis by Tissue Origami