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Francesco Stellacci

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Publications associées (214)

FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice

Francesco Stellacci

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting motor neurons. In ALS mice, neurodegeneration is associated with the proliferative restorative attempts of ependymal stem progenitor cells (epSPCs) that normally lie i ...

2019

Local photo-mechanical stiffness revealed in gold nanoparticles supracrystals by ultrafast small-angle electron diffraction

Fabrizio Carbone, Francesco Stellacci, Giulia Fulvia Mancini, Javier Reguera Gomez, Francesco Pennacchio, Tatiana Latychevskaia

We demonstrate that highly ordered two-dimensional crystals of ligand-capped gold nanoparticles display a local photo-mechanical stiffness as high as that of solids such as graphite. In out-of-equilibrium electron diffraction experiments, a strong temperat ...

2019

Stable Ultraconcentrated and Ultradilute Colloids of CsPbX3 (X = Cl, Br) Nanocrystals Using Natural Lecithin as a Capping Ligand

Francesco Stellacci, Quy Ong Khac

Attaining thermodynamic stability of colloids in a broad range of concentrations has long been a major thrust in the field of colloidal ligand-capped semiconductor nanocrystals (NCs). This challenge is particularly pressing for the novel NCs of cesium lead ...

AMER CHEMICAL SOC2019

Nanoparticles interaction with viruses

Francesco Stellacci

AMER CHEMICAL SOC2019

Modular soft robotic microdevices for dexterous biomanipulation

Lucio Feo Pancaldi-Giubbini, Francesco Stellacci, Ahmet Bekdemir, Mahmut Selman Sakar, Raquel Filipa Penacho Parreira, Ece Özelçi, Berna Ayse Özkale Edelmann, Murat Kaynak

We present a methodology for building biologically inspired, soft microelectromechanical systems (MEMS) devices. Our strategy combines several advanced techniques including programmable colloidal self-assembly, light-harvesting with plasmonic nanotransduce ...

2019

Determination and evaluation of the nonadditivity in wetting of molecularly heterogeneous surfaces

Francesco Stellacci, Quy Ong Khac, Sylvie Roke, Zhi Luo, Michele Ceriotti, Filip Kovacik, David Mark Wilkins, Halil Ibrahim Okur, Anna Murello

The interface between water and folded proteins is very complex. Proteins have "patchy" solvent-accessible areas composed of domains of varying hydrophobicity. The textbook understanding is that these domains contribute additively to interfacial properties ...

National Academy of Sciences2019

Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells

Francesco Stellacci, Randy Patrick Carney

Particles that preferentially partition to a specific cellular subunit, such as the nucleus, mitochondria, or the cytoskeleton, are of relevance to a number of applications, including drug delivery, genetic manipulation, or self-assembly. Here, hierarchica ...

WILEY-V C H VERLAG GMBH2019

Hydrophobic interactions in soft matter

Francesco Stellacci

AMER CHEMICAL SOC2019

Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

Francesco Stellacci, Weina Liu

The surface of proteins is heterogeneous with sophisticated but precise hydrophobic and hydrophilic patches, which is essential for their diverse biological functions. To emulate such distinct surface patterns on macromolecules, we used rigid spherical syn ...

2019

Multidimensional Characterization of Mixed Ligand Nanoparticles Using Small Angle Neutron Scattering

Francesco Stellacci, Quy Ong Khac, Stefan Guldin, Zhi Luo, Ye Yang

The properties of ligand protected gold nanoparticles are determined by the synergistic interplay of their structural components, including the metal core, the ligand shell, and the solvation layer. However, the simultaneous characterization of all these c ...

AMER CHEMICAL SOC2019

Microstructured Fibers for the Production of Food

Véronique Michaud, Francesco Stellacci, Federica Sordo, Fabien Sorin, Yunpeng Qu, Emma-Rose Janecek

Food engineering faces the difficult challenge of combining taste, i.e., tailoring texture and rheology of food matrices with the balanced intake of healthy nutrients. In materials science, fiber suspensions and composites have been developed as a versatil ...

Wiley2019

Ubiquitous aluminium contamination in water and amyloid hybrid membranes as a sustainable possible solution

Raffaele Mezzenga, Francesco Stellacci, Malvina Julia Ida Pauchard

We develop a membrane technology based on amyloid fibrils to remove aluminium from water and minimize its exposure to humans. We study aluminium adsorption by amyloid fibrils by evaluating the binding isotherms, the thermodynamics and the effects of differ ...

Royal Society of Chemistry2019

Celebrating 10 years of Nanoscale

Francesco Stellacci, Markus Niederberger

ROYAL SOC CHEMISTRY2019

An Atomistic Look into Bio-inspired Nanoparticles and their Molecular Interactions with Cells

Alke Fink, Pablo Campomanes Ramos, Stefano Vanni, Francesco Stellacci

Nanoparticles (NPs) have sizes that approach those of pathogens and they can interact with the membranes of eukaryotic cells in an analogous fashion. Typically, NPs are taken up by the cell via the plasma membrane by receptor-mediated processes and subsequ ...

SWISS CHEMICAL SOC2019

Amorphous CaCO3: Influence of the Formation Time on Its Degree of Hydration and Stability

Camelia Borca, Francesco Stellacci, Huachuan Du, Esther Amstad, Anna Murello, Mathias Steinacher

Calcium carbonate (CaCO3) is one of the most abundant biominerals that is prevalent in rocks and often used as a structural material in marine animals. Many of these natural CaCO3-based materials display excellent mechanical properties that are difficult t ...

2018

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism

Francesco Stellacci, Paulo Henrique Jacob Silva, Marie Mueller, Ahmet Bekdemir, Samuel Thomas Jones, Emma-Rose Janecek, Valeria Cagno

Viral infections kill millions yearly. Available antiviral drugs are virus-specific and active against a limited panel of human pathogens. There are broad-spectrum substances that prevent the first step of virus–cell interaction by mimicking heparan sulfat ...

2018

Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants

Francesco Stellacci, Evangelia-Nefeli Athanasopoulou

Collagen-rich tissues in the cornea exhibit unique and highly organized extracellular matrix ultrastructures, which contribute to its high load-bearing capacity and light transmittance. Corneal collagen fibrils are controlled during development by small le ...

WILEY-V C H VERLAG GMBH2018

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Francesco Stellacci

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FM19G11-Loaded Gold Nanoparticles Enhance the Proliferation and Self-Renewal of Ependymal Stem Progenitor Cells Derived from ALS Mice

Local photo-mechanical stiffness revealed in gold nanoparticles supracrystals by ultrafast small-angle electron diffraction

Stable Ultraconcentrated and Ultradilute Colloids of CsPbX3 (X = Cl, Br) Nanocrystals Using Natural Lecithin as a Capping Ligand

Nanoparticles interaction with viruses

Modular soft robotic microdevices for dexterous biomanipulation

Determination and evaluation of the nonadditivity in wetting of molecularly heterogeneous surfaces

Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells

Hydrophobic interactions in soft matter

Patchy Amphiphilic Dendrimers Bind Adenovirus and Control Its Host Interactions and in Vivo Distribution

Multidimensional Characterization of Mixed Ligand Nanoparticles Using Small Angle Neutron Scattering

Microstructured Fibers for the Production of Food

Ubiquitous aluminium contamination in water and amyloid hybrid membranes as a sustainable possible solution

Celebrating 10 years of Nanoscale

An Atomistic Look into Bio-inspired Nanoparticles and their Molecular Interactions with Cells

Amorphous CaCO3: Influence of the Formation Time on Its Degree of Hydration and Stability

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism

Cyclodextrin Modulated Type I Collagen Self-Assembly to Engineer Biomimetic Cornea Implants

Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering

Edible sensors for meat and seafood freshness

Evolution of Nanoparticle Protein Corona across the Blood-Brain Barrier