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Cristina Granziera

Cette personne n’est plus à l’EPFL

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Publications associées (61)

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alexis Roche, Ying-Chia Lin

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alexis Roche, Ying-Chia Lin

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

FID-guided retrospective motion correction based on autofocusing

Rolf Gruetter, Gunnar Krüger, Tobias Kober, Cristina Granziera, Maryna Volodimirivna Waszak

This work investigates the possibility of using FID navigator signals to improve the performance of a recently proposed autofocusing-based retrospective motion correction technique. FID navigators were incorporated into an MP-RAGE sequence and 3 subjects w ...

2014

Volume-based vs. voxel-based brain morphometry in Alzheimer's disease prediction

Meritxell Bach Cuadra, Reto Meuli, Bénédicte Marie Maréchal, Delphine Ribes Lemay, Daniel Andreas Schmitter, Gunnar Krüger, Ahmed Abdulkadir, Cristina Granziera, Alessandro Daducci, Alexis Roche

Voxel-based morphometry from conventional T1-weighted images has proved effective to quantify Alzheimer's disease (AD) related brain atrophy and to enable accurate automated classification of AD patients, mild cognitive impaired (MCI) patients and elderly ...

Proceedings of 23rd International Society for Magnetic Resonance in Medicine (ISMRM) Conference2014

Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Djalel Eddine Meskaldji, Reto Meuli, François Lazeyras, Gunnar Krüger, Tobias Kober, Cristina Granziera, Alessandro Daducci, Alexis Roche

Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Public Library of Science2013

Magnetization transfer-based 3D visualization of foot peripheral nerves

Giulio Gambarota, Bénédicte Marie Maréchal, Gunnar Krüger, Cristina Granziera

PURPOSE: To investigate magnetization transfer (MT) effects as a new source of contrast for imaging and tracking of peripheral foot nerves. MATERIALS AND METHODS: Two sets of 3D spoiled gradient-echo images acquired with and without a saturation pulse were ...

Wiley-Blackwell2013

Structural abnormalities in the thalamus of migraineurs with aura: a multiparametric study at 3T

Nouchine Hadjikhani, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

Background and objectives: The thalamus exerts a pivotal role in pain processing and cortical excitability control, and migraine is characterized by repeated pain attacks and abnormal cortical habituation to excitatory stimuli. This work aimed at studying ...

Wiley-Blackwell2013

Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe

Nouchine Hadjikhani, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

The involvement of the cerebellum in migraine pathophysiology is not well understood. We used a biparametric approach at high-field MRI (3 T) to assess the structural integrity of the cerebellum in 15 migraineurs with aura (MWA), 23 migraineurs without aur ...

Springer US2013

MP2RAGE multiple sclerosis magnetic resonance imaging at 3 T

Reto Meuli, Rolf Gruetter, Delphine Ribes Lemay, Gunnar Krüger, Tobias Kober, Cristina Granziera

Objectives: Lesion detection and characterization in multiple sclerosis (MS) are an essential part of its clinical diagnosis and an important research field. In this pilot study, we applied the recently introduced two inversion-contrast magnetization-prepa ...

2012

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field

Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

2012

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast MRI study at 3T

Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

2012

Structural abnormalities in the thalamus of migraine patients: a multi-parametric study at high field

Nouchine Hadjikhani, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

2012

A new early and automated MRI-based predictor of motor improvement after stroke

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Reto Meuli, Nouchine Hadjikhani, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche, Richard Frackowiak

Objectives: In this study, we investigated the structural plasticity of the contralesional motor network in ischemic stroke patients using diffusion magnetic resonance imaging (MRI) and explored a model that combines a MRI-based metric of contralesional ne ...

2012

Effects of MRI scan acceleration on brain volume measurement consistency

Bénédicte Marie Maréchal, Gunnar Krüger, Cristina Granziera

To evaluate the effects of recent advances in magnetic resonance imaging (MRI) radiofrequency (RF) coil and parallel imaging technology on brain volume measurement consistency. ...

Wiley-Blackwell2012

Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Xavier Gigandet, Reto Meuli, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Leila Cammoun

There is growing interest in understanding the role of the non-injured contra-lateral hemisphere in stroke recovery. In the experimental field, histological evidence has been reported that structural changes occur in the contra-lateral connectivity and cir ...

2011

Towards a diffusion image processing validation and accuracy prediction framework

Gloria Menegaz, Jean-Philippe Thiran, Meritxell Bach Cuadra, Alia Lemkaddem, Cristina Granziera, Alessandro Daducci

Validation is the main bottleneck preventing the adoption of many medical image processing algorithms in the clinical practice. In the classical approach, a-posteriori analysis is performed based on some objective metrics. In this work, a different approac ...

2011

In-vivo magnetic resonance imaging of the structural core of the Papez circuit in humans

Reto Meuli, Nouchine Hadjikhani, Cristina Granziera

Papez circuit is one of the major pathways of the limbic system, and it is involved in the control of memory and emotion. Structural and functional alterations have been reported in psychiatric, neurodegenerative, and epileptic diseases. Despite the clinic ...

2011

Cerebellar Cortical Layers: In Vivo Visualization with Structural High-Field-Strength MR Imaging

Rolf Gruetter, Wietske Van der Zwaag, Gunnar Krüger, José Pedro Rebelo Ferreira Marques, Cristina Granziera

Purpose: To perform in vivo imaging of the cerebellum with an in-plane resolution of 120 mm to observe its cortical granular and molecular layers by taking advantage of the high signal-to-noise ratio and the increased magnetic susceptibility-related contra ...

2010

On the reproducibility and anatomical correspondence of DSI tractography

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Leila Cammoun

Diffusion spectrum imaging (DSI) is increasingly explored in clinical research. The quantitative value of the DSI technique, however, has still to be established. In this context, a better understanding of the reproducibility and the anatomical corresponde ...

2010

Diffusion Spectrum Imaging Shows the Structural Basis of Functional Cerebellar Circuits in the Human Cerebellum In Vivo

Reto Meuli, Van Jay Wedeen, Nouchine Hadjikhani, Cristina Granziera

Background: The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits. Identifying the structural bases of cerebellar neuronal networks in humans in vi ...

2009

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