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Cristina Ramona Cudalbu

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Publications associées (122)

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease

Cristina Ramona Cudalbu, Veronika Rackayová

Type C hepatic encephalopathy (type C HE) is increasingly suspected in children with chronic liver disease (CLD), and believed to underlie long-term neurocognitive difficulties. The molecular underpinnings of type C HE in both adults and children are incom ...

Nature Research2020

B(0)shimming for in vivo magnetic resonance spectroscopy: Experts' consensus recommendations

Rolf Gruetter, Cristina Ramona Cudalbu

Magnetic resonance spectroscopy (MRS) and spectroscopic imaging (MRSI) allow the chemical analysis of physiological processes in vivo and provide powerful tools in the life sciences and for clinical diagnostics. Excellent homogeneity of the static B(0)magn ...

2020

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts' consensus recommendations

Bernard Lanz, Cristina Ramona Cudalbu

With a 40-year history of use for in vivo studies, the terminology used to describe the methodology and results of magnetic resonance spectroscopy (MRS) has grown substantially and is not consistent in many aspects. Given the platform offered by this speci ...

WILEY2020

Contribution of macromolecules to brain H-1 MR spectra: Experts' consensus recommendations

Rolf Gruetter, Lijing Xin, Hongxia Lei, Cristina Ramona Cudalbu, Veronika Rackayová, Dunja Simicic

Proton MR spectra of the brain, especially those measured at short and intermediate echo times, contain signals from mobile macromolecules (MM). A description of the main MM is provided in this consensus paper. These broad peaks of MM underlie the narrower ...

WILEY2020

MP-PCA denoising dramatically improves SNR in large-sized MRS data: an illustration in diffusion-weighted MRS

Cristina Ramona Cudalbu, Ileana Ozana Jelescu

2020

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

Rolf Gruetter, Cristina Ramona Cudalbu

Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and has been shown to aid the clinical management of several brain diseases. Although most modern clinical MR scanners support MRS capabilities, routine use is largely res ...

Wiley2019

Antibiotic Rifaximin for Treatment of Chronic Liver Disease-Induced HE: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism on BDL Rats

Rolf Gruetter, Cristina Ramona Cudalbu, Emmanuelle Ines Flatt, Dario Sessa, Stefanita-Octavian Mitrea

LIPPINCOTT WILLIAMS & WILKINS2019

Reply to: "Magnetic resonance spectroscopy: A surrogate marker of hepatic encephalopathy?''

Cristina Ramona Cudalbu

2019

Cholestasis Decreases Dendritic Spine Density in a Rat Hippocampal Organotypic Culture

Cristina Ramona Cudalbu

LIPPINCOTT WILLIAMS & WILKINS2019

In Vivo Longitudinal 1H MRS Study of Hippocampal, Cereberal and Striatal Metabolic Changes in the Adult Brain Using an Animal Model of Chronic Hepatic Encephalopathy

Katarzyna Pierzchala, Cristina Ramona Cudalbu, Veronika Rackayová, Dario Sessa, Stefanita-Octavian Mitrea, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

Probiotics Combined With Rifaximin for the Treatment of Chronic Hepatic Encephalopathy: A Longitudinal In Vivo 1H-MRS Study of Brain Metabolism Using BDL Rats

Rolf Gruetter, Cristina Ramona Cudalbu, Emmanuelle Ines Flatt, Dario Sessa, Stefanita-Octavian Mitrea

LIPPINCOTT WILLIAMS & WILKINS2019

Neurometabolism in Grey Matter of Children With Chronic Liver Disease or Portosystemic Shunting: A 1H-MRS Study at 7T

Sarah Lachat, Lijing Xin, Cristina Ramona Cudalbu

LIPPINCOTT WILLIAMS & WILKINS2019

Brain Regional Susceptibility to Oxidative Stress in a Rat Model of Chronic Hepatic Encephalopathy: In-Vivo 1H MRS, Ex-Vivo ESR Spectroscopy and Histology Findings

Andrzej Sienkiewicz, Rolf Gruetter, Katarzyna Pierzchala, Cristina Ramona Cudalbu, Veronika Rackayová, Dario Sessa, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Katarzyna Pierzchala, Cristina Ramona Cudalbu, Jocelin Grosse, Veronika Rackayová

Background & Aims: The sequence of events in hepatic encephalopathy (HE) remains unclear. Using the advantages of in vivo 1H-MRS (9.4T) we aimed to analyse the time-course of disease in an established model of type C HE by analysing the longitudinal change ...

2019

Bile Acids And Ammonium Contribute To Changes In Dendritic Spine Distribution In An Organotypic Culture Of Rat Hippocampus

Cristina Ramona Cudalbu

WILEY2019

Brain Edema in Chronic Hepatic Encephalopathy

Cristina Ramona Cudalbu

Brain edema is a common feature associated with hepatic encephalopathy (HE). In patients with acute HE, brain edema has been shown to play a crucial role in the associated neurological deterioration. In chronic HE, advanced magnetic resonance imaging (MRI) ...

ELSEVIER - DIVISION REED ELSEVIER INDIA PVT LTD2019

Hippocampal and Cerebellar Astrocytes Morphological Alterations in a Rat Model of Chronic Hepatic Encephalopathy

Katarzyna Pierzchala, Cristina Ramona Cudalbu, Dunja Simicic

LIPPINCOTT WILLIAMS & WILKINS2019

In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

Bernard Lanz, Rolf Gruetter, Carole Poitry-Yamate, Cristina Ramona Cudalbu, Marta Lai

Glioblastoma are notorious for their highly invasive growth, diffusely infiltrating adjacent brain structures that precludes complete resection, and is a major obstacle for cure. To characterize this "invisible" tumor part, we designed a high resolution mu ...

2018

Metabolic And Transcriptional Profiles Of Gbm Invasion: Comparison Of Patients And Paired Patient Derived Xenografts Using1H Magnetic Resonance Spectroscopy And Imaging (7T And 14T) And Rna-Sequencing

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu, Mario Gaetano Lepore, Marta Lai

OXFORD UNIV PRESS INC2018

In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

Bernard Lanz, Rolf Gruetter, Carole Poitry-Yamate, Cristina Ramona Cudalbu, Marta Lai, Corina Mihaela Berset

In vivo (13)C magnetic resonance spectroscopy (MRS) enables the investigation of cerebral metabolic compartmentation while, e.g. infusing (13)C-labeled glucose. Metabolic flux analysis of (13)C turnover previously yielded quantitative information of glutam ...

2018

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