Hongxia Lei

Cette personne n’est plus à l’EPFL

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Publications associées (68)

Neuroprotective role of lactate after cerebral ischemia

Pierre Magistretti, Rolf Gruetter, Hongxia Lei, Jonathan Thevenet

It is well established that lactate can be used as an energy substrate by the brain by conversion to pyruvate and a subsequent oxidation in the mitochondria. Knowing the need for readily metabolizable substrates directly after ischemia and the protective e ...

2009

Time-resolved measurement of rat brain glycogen absolute concentration in vivo

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

Wiley-Blackwell2009

Snapshot gradient-recalled echo-planar images of rat brains at long echo time at 9.4 T

Rolf Gruetter, Hongxia Lei, Nathalie Just

With improved B-0 homogeneity along with satisfactory gradient performance at high magnetic fields, snapshot gradient-recalled echo-planar imaging (GRE-EPI) would perform at long echo times (TEs) oil the order of T-2*, which intrinsically allows obtaining ...

Elsevier2008

Non-invasive quantification of brain glycogen absolute concentration

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

Minimization of Nyquist ghosting for fMRI at Ultra-High Fields Based on a ‘negative Read-Out Gradient’

Rolf Gruetter, Hongxia Lei, Nathalie Just, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques

2008

Glucose and glycogen content in rat hypothalamus at euglycemia and hypoglycemia

Rolf Gruetter, Hanne Frenkel, Hongxia Lei, Carole Poitry-Yamate

Wiley-Blackwell2007

Direct validation of in vivo localized 13C MRS measurements of brain glycogen

Rolf Gruetter, Hongxia Lei

With the use of localized 13C MRS in conjunction with [1-(13)C]-D-glucose infusion, it is possible to study brain glycogen metabolism in vivo. The purpose of this study was to validate in vivo 13C MRS measurements by comparing them with results from a stan ...

Wiley-Blackwell2007

Effect of chronic hypoglycaemia on glucose concentration and glycogen content in rat brain: A localized 13C NMR study

Rolf Gruetter, Hongxia Lei

While chronic hypoglycaemia has been reported to increase unidirectional glucose transport across the blood-brain barrier (BBB) and to increase GLUT1 expression at the endothelium, the effect on steady-state brain d-glucose and brain glycogen content is cu ...

Wiley-Blackwell2006

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