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Rolf Gruetter

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Publications associées (418)

In vivo H-1 NMR measurement of glycine in rat brain at 9.4 T at short echo time

Chiara Perazzolo, Rolf Gruetter, Giulio Gambarota, Lijing Xin

Glycine is an amino acid present in mammalian brain, where it acts as an inhibitory and excitatory neurotransmitter. The two detectable protons of glycine give rise to a singlet at 3.55 ppm that overlaps with the more intense myo-inositol resonances, and i ...

Wiley-Blackwell2008

White matter changes in lipopolysaccharide (LPS) treated fetal sheep measured by high field diffusion tensor imaging (DTI)

François Lazeyras, Rolf Gruetter, Yohan Van de Looij

2008

Fast Bias Field Correction for 9.4 Tesla Magnetic Resonance Imaging

Murat Kunt, Jean-Philippe Thiran, Meritxell Bach Cuadra, Nicolas Kunz, Rolf Gruetter, Nathalie Just, Xavier Pena Pina

In this paper the problem of intensity inhomogeneity at high magnetic field on magnetic resonance images is addressed. Specifically, rat brain images at 9.4T acquired with a surface coil are bias corrected. We propose a low- pass frequency model that takes ...

2008

Proton T-2 relaxation time of J-coupled cerebral metabolites in rat brain at 9.4T

Rolf Gruetter, Giulio Gambarota, Lijing Xin

Knowledge of proton T-2 relaxation time of metabolites is essential for proper quantitation of metabolite concentrations in localized proton spectroscopy, especially at moderate to long TEs. Although the T-2 relaxation time of singlets, such as that of cre ...

Wiley-Blackwell2008

Magnetic Resonance Spectroscopy and Imaging at 9.4T in P4 rat pup brain following cerebral hypoxia-ischemia

Nicolas Kunz, Rolf Gruetter, Yohan Van de Looij

2008

Glucose homeostasis is altered in transgenic mice with brain specific knockout of the mitochondrial enzyme glutamate dehydrogenase

Rolf Gruetter

Springer Verlag2008

Glucose transport and neurochemical profile in the hippocampus of STZ-induced diabetic rats under hyper- and euglycaemia studied by in vivo 1H MRS at 9.4 T

Rolf Gruetter, João Miguel das Neves Duarte

2008

Comparison of Two Approaches to Model the Macromolecule Spectrum for the Quantification of Short TE 1H MRS Spectra at 14.1T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

Localized 1H[13C] NMR Measurement of N-acetyl-aspartate Turnover in Rat Brain

Rolf Gruetter, Lijing Xin, Hanne Frenkel

2008

Comparison of two approaches to model the macromolecule spectrum for the quantification of short TE H-1 MRS spectra

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Accurate assessment of the macromolecule contributions in short echo-time proton MRS spectra is important for a reliable quantification of the neurochemical profile. The aim of the present study was to assess two approaches based on using LCModel, which ta ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2008

Principles of operation of a DNP prepolarizer coupled to a rodent MRI scanner

Arnaud Comment, Jacques Van Der Klink, Rolf Gruetter, Sami Jannin, Fiodar Kurdzesau

A dynamic nuclear polarization prepolarizer was developed and coupled to a 9.4 T rodent magnetic resonance imaging scanner in order to perform in vivo hyperpolarization experiments. In the present paper, emphasis is put on methods and hardware performance ...

2008

Quantitative proton spectroscopic imaging of the neurochemical profile in rat brain with microliter resolution at ultra-short echo times

Rolf Gruetter, Giulio Gambarota

Proton spectroscopy allows the simultaneous quantification of a high number of metabolite concentrations termed the neurochemical profile. The spin echo full intensity acquired localization (SPECIAL) scheme with an echo time of 2.7 ms was used at 9.4T for ...

Wiley-Blackwell2008

Comparison of the T1 of the neurochemical profile in rat brain at 9.4T and 14.1T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

2008

MRS study of human glioma-initiating cells grown in the brain of nude Mice

Rolf Gruetter, Cristina Ramona Cudalbu

2008

Snapshot gradient-recalled echo-planar images of rat brains at long echo time at 9.4 T

Rolf Gruetter, Hongxia Lei, Nathalie Just

With improved B-0 homogeneity along with satisfactory gradient performance at high magnetic fields, snapshot gradient-recalled echo-planar imaging (GRE-EPI) would perform at long echo times (TEs) oil the order of T-2*, which intrinsically allows obtaining ...

Elsevier2008

High-resolution fMRI at 7T using surface or array rf-coils

Rolf Gruetter, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques

2008

Non-invasive quantification of brain glycogen absolute concentration

Sabrina Laus, Rolf Gruetter, Ruud van Heeswijk, Lijing Xin, Hanne Frenkel, Hongxia Lei

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Ultra-short echo-time proton single voxel spectra of rat brain were obtained on a 14.1 T 26 cm horizontal bore system. At this field, the fitted linewidth in the brain tissue of adult rats was about 11 Hz. New, separated resonances ascribed to phosphocholi ...

Academic Press Inc - Elsevier Science2008

Hahn T2 Relaxation Times of the Neurochemical Profile at 14.1T in the in vivo Rat Brain

Rolf Gruetter, Giulio Gambarota, Lijing Xin, Cristina Ramona Cudalbu

2008

Comparison of three commercially available radio frequency coils for human brain imaging at 3 Tesla

Andreas Joosten, Rolf Gruetter, Wietske Van der Zwaag

Objective To evaluate a transverse electromagnetic (TEM), a circularly polarized (CP) (birdcage), and a 12-channel phased array head coil at the clinical field strength of B (0) = 3T in terms of signal-to-noise ratio (SNR), signal homogeneity, and maps of ...

2008

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