Publications de Romain Wyss | EPFL Graph Search

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Biomarker detection and diagnosis are important steps in the prevention and the treatment of a disease. There is an increasing need for utmost sensitive and robust sensing devices; in this framework, subwavelength (metal) pores could contribute to a concep ...

The method analyzes biological fluids collected from patients, and uses attenuated total reflecting (ATR) sensors and spectral analysis by Fourier transform infrared spectroscopy (FTIR) to form a spectral fingerprint of extracellular vesicles (EVs) isolate ...

We report on a generic method to detect and iden- tify the molecular profile of exosomes either derived from cultured cell lines or isolated from biofluids. Exosomes are nanovesicles shed by cells into their microenvironment and carry the molecular identit ...

Neurotransmitter-gated ion channels of the Cys-loop receptor family mediate fast neurotransmission throughout the nervous system. The molecular processes of neurotransmitter binding, subsequent opening of the ion channel and ion permeation remain poorly un ...

Cellular signaling is classically investigated by measuring optical or electrical properties of single or populations of living cells. Here we show that ligand binding to cell surface receptors and subsequent activation of signaling cascades can be monitor ...

Cells secrete extracellular vesicles (EVs) into their microenvironment that act as mediators of intercellulard communication under physiological conditions and in this context also actively participate in spreading various diseases. Large efforts are curre ...

SAS-6 proteins are thought to impart the ninefold symmetry of centrioles, but the mechanisms by which their assembly occurs within cells remain elusive. In this paper, we provide evidence that the N-terminal, coiled-coil, and C-terminal domains of HsSAS-6 ...

Romain Wyss

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Nanostructured Surfaces for the Detection of Single-Particles and Single-Molecules

Use of fourier transform infrared spectroscopy analysis of extracellular vesicles isolated from body fluids for diagnosing, prognosing and monitoring pathophysiological states and method therfor

Molecular screening of cancer-derived exosomes by surface plasmon resonance spectroscopy

X-ray structure of the mouse serotonin 5-HT3 receptor

Downscaling the Analysis of Complex Transmembrane Signaling Cascades to Closed Attoliter Volumes

Molecular and Dimensional Profiling of Highly Purified Extracellular Vesicles by Fluorescence Fluctuation Spectroscopy

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells

A Zeptoliter Volume Meter for Analysis of Single Protein Molecules

Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking