Recherche

Afficher tous les résultats pour

Accueil

Personne

Kay Severin

Cette personne a quitté l’EPFL

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (205)

Page 3 sur 11

Highly cross-linked polymers containing N,N ',N ''-chelate ligands for the Cu(II)-mediated hydrolysis of phosphoesters

Rosario Scopelliti, Kay Severin, Alexander Schiller

Three immobilized Cu(II) complexes were generated by the following: (a) homopolymerization of the N,N',N '' chelate ligand tris[2-(1-vinylimidazolyl)]phosphine (1) and subsequent metalation with CuCl2; (b) copolymerization of 1 with ethyleneglycol dimethac ...

2005

Synthesis of Molecular Nanostructures by Multicomponent Condensation Reactions in a Ball Mill

Rosario Scopelliti, Kay Severin, Nicolas Christinat, Justus Tönnemann, Burçak Içli

The condensation of multiple building blocks in a ball mill allows molecular cages with a size up to 3.1 nm to be built. ...

2009

Modulating the Steric, Electronic, and Catalytic Properties of Cp* Ruthenium Half-Sandwich Complexes with β-Diketiminato Ligands

Paul Joseph Dyson, Rosario Scopelliti, Kay Severin, Andrew Douglas Phillips, Katrin Anne Thommes

Five different types of β-diketiminate ligands, bearing electron-donating to strongly electron-withdrawing substituents, were synthesized and used in the synthesis of Cp* ruthenium complexes (Cp* = η5-C5Me5). One series consists of complexes with a covalen ...

American Chemical Society2011

Fluorinated Tetraarylethenes: Universal Tags for the Synthesis of Solid State Luminogens

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Euro Solari, Abdusalom Suleymanov, Albert Ruggi

The aggregation-induced emission properties of tetraarylethenes (TAEs) have led to numerous applications in chemistry, biology, and materials science. Herein, we describe two fluorinated tetraarylethenes, which can be employed as universal tags for the syn ...

Wiley-VCH Verlag GmbH2022

Metal-Stabilized Boronate Ester Cages

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Erica Giraldi

Molecular cages with arylboronate ester caps at the vertices are described. The cages were obtained by metal-templated polycondensation reactions of a tris(2-formylpyridine oxime) ligand with arylboronic acids. Suited templates are triflate or triflimide s ...

2021

Cross-Reactive Sensor Arrays for the Detection of Peptides in Aqueous Solution by Fluorescence Spectroscopy

Kay Severin, Sébastien Rochat, Friederike Gundula Marie Zaubitzer

A simple but powerful method for the sensing of peptides in aqueous solution has been developed. The transition-metal complexes [PdCl2(en)], [{RhCl2Cp*}2], and [{RuCl2(p-cymene)} 2] were combined with six different fluorescent dyes to build a cross-reactiv ...

2010

An Imine-Based Molecular Cage with Distinct Binding Sites for Small and Large Alkali Metal Cations

Rosario Scopelliti, Kay Severin, Clément Schouwey

The synthesis of a cylindrical, imine-based cage composed of two trimeric metallamacrocycles is described. The cage acts as a heterotopic receptor for alkali metal cations. The small cations Li+, Na+, and K+ bind to the outside of the cage with good select ...

Wiley-V C H Verlag Gmbh2013

Preparation and medical use of triazenes

Kay Severin, Gregor Kiefer

The present invention relates to a novel method for preparing triazenes. Further, the invention relates to novel triazenes and the use of N2O for preparing a compound comprising a triazene group. Further, the invention relates to the use of the novel triaz ...

2015

Organometallic complexes that interconvert between trimeric and monomeric structures as a function of pH and their effect on human cancer and fibroblast cells

Paul Joseph Dyson, Rosario Scopelliti, Kay Severin, Wee Han Ang, Zacharias Immanuel Grote

Organometallic half-sandwich complexes based on ruthenium with aminomethyl-substituted 3-hydroxy-2-pyridone ligands exist in aqueous solution as monomeric O,O′-chelate complexes or trimeric metallamacrocycles depending upon the pH. We hypothesized that adm ...

2009

Dicarboxylate-Bridged Ruthenium Complexes as Building Blocks for Molecular Nanostructures

Rosario Scopelliti, Kay Severin, Benan Kilbas

Ruthenium complexes with bridging dicarboxylate ligands were combined with 1,2-di-4-pyridylethylene (dpe), 2,4,6-tri-4-pyridyltriazine (4-tpt), or 2,4,6-tri-3-pyridyltriazine (3-tpt) to give a tetranuclear rectangle or hexanuclear coordination cages. The c ...

2012

1,2‐Bis‐Triazenylarenes Enable Vicinal Sandmeyer‐Type Reactions

Kay Severin, Farzaneh Fadaei Tirani, Anastasia Gitlina, Christeena Mathew, Alexandre Tcheul-Young Genoux

The introduction of two nucleophiles in the vicinal position of arenes via Sandmeyer‐type reactions is compromised by the problematic diazotization of ortho‐diaminoarenes. Herein, it is shown that vicinal substitution reactions are facilitated by the use ...

Wiley2025

Synthesis of Triazenes with Nitrous Oxide

Paul Joseph Dyson, Rosario Scopelliti, Kay Severin, Tina Riedel, Gregor Kiefer

Triazenes are valuable compounds in organic chemistry and numerous applications have been reported. Furthermore, triazenes have been investigated extensively as potential antitumor drugs. Here, we describe a new method for the synthesis of triazenes. The p ...

Wiley-Blackwell2015

LiBF4‐Induced Rearrangement and Desymmetrization of a Palladium‐Ligand Assembly

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Sylvain Alexandre Marie Sudan

Thirteen palladium-ligand assemblies with different structures and topologies were investigated for the ability to bind lithium ions. In one case, the addition of LiBF4 resulted in a profound structural rearrangement, converting a dincluclear [Pd2L4]2 comp ...

Wiley-VCH Verlag GmbH2022

Alkynyl Triazenes as Fluoroalkyne Surrogates: Regioselective Access to 4-Fluoro-2-pyridones by a Rh(III)-Catalyzed C–H Activation–Lossen Rearrangement–Wallach Reaction

Kay Severin, Nicolai Cramer, Carl Thomas Bormann, Jin Fay Tan

Fluorinated pyridones are an important scaffold displaying relevant biological activities. Efficient assembly strategies of pyridones are transition metal-catalyzed C–H annulations with alkynes. The inaccessibility and extreme lability of fluoro alkynes re ...

2020

Reactions of Grignard Reagents with Nitrous Oxide

Rosario Scopelliti, Kay Severin, Euro Solari, Alexander Tskhovrebov

The chemical activation of nitrous oxide (N2O) can be achieved by organocalcium, organosodium, and organolithium compounds. Grignard reagents, on the other hand, are believed to be inert. We demonstrate that this generalization is not correct. Some aliphat ...

American Chemical Society2014

Identification of a Heteroleptic Pd6L6L′6 Coordination Cage by Screening of a Virtual Combinatorial Library

Rosario Scopelliti, Kay Severin, Farzaneh Fadaei Tirani, Suzanne Maria Jansze, Rujin Li, Sylvain Alexandre Marie Sudan

The design of structurally defined heteroleptic coordination cages is a challenging task, and only few examples are known to date. Here we describe a selection approach that allowed the identification of a novel hexanuclear Pd cage containing two types of ...

2021

A simple fluorescence assay for the detection of fluoride in water at neutral pH

Kay Severin, Sébastien Rochat

A simple assay for the detection of fluoride in water by fluorescence spectroscopy was developed. The assay is based on commercially available reagents and allows sensing of fluoride in the low millimolar concentration range with high selectivity over othe ...

Royal Society of Chemistry2011

Anionic Bipyridyl Ligands for Applications in Metallasupramolecular Chemistry

Rosario Scopelliti, Kay Severin, Mathieu Jérémie Marmier, Clément Schouwey, Mirela Pascu

The facile synthesis of anionic bipyridyl ligands with dinuclear clathrochelate cores is described. These metalloligands can be obtained in high yields by the reactions of M(ClO4)(2)(H2O)(6) (M: Zn, Mn, or Co) with 4-pyridylboronic acid and 2,6-diformyl-4- ...

Wiley-Blackwell2014

Reversible disassembly of metallasupramolecular structures mediated by a metastable-state photoacid

Kay Severin, Suzanne Maria Jansze, Giacomo Cecot

The addition of a metastable-state photoacid to solutions containing metal–ligand assemblies renders the systems light responsive. Upon irradiation, proton transfer from the photoacid to the ligand is observed, resulting in disassembly of the metallasupram ...

2018

A ratiometric fluorescence sensor for caffeine

Laurane Favre, Kay Severin, Anne-Clémence Corminboeuf, Nicolas Luisier, Albert Ruggi, Nicolas David Gaeng

The dye disodium 3,4:3’,4’-bibenzo[b]thiophene-2,2’-disulfonate can be used as molecular probe for the fluorimetric detection of caffeine in aqueous solution. The fluorescence response is attributed to non-covalent interactions of caffeine with the dye in ...

Royal Society of Chemistry2012