Background Since the emergence of diffusion tensor imaging, a lot of work has been done to better understand the properties of diffusion MRI tractography. However, the validation of the reconstructed fiber connections remains problematic in many respects. ...

2008

Mapping the Structural Core of Human Cerebral Cortex

Xavier Gigandet, Patric Hagmann, Reto Meuli, Leila Cammoun, Olaf Sporns

2008

Quantitative Validation of MR Tractography Using the CoCoMac Database

Xavier Gigandet, Patric Hagmann, Reto Meuli, Van Jay Wedeen, Olaf Sporns

2008

Fast-Marching Tractography for Connection Matrix (Fast-TraC)

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Leila Cammoun

Although high angular resolution diffusion MRI techniques are able to solve multiple intra-voxel fiber orientations, the usual streamline Diffusion Spectrum Imaging (DSI) tractography algorithms present some limitations in their ability to map complex fibe ...

2008

Dysconnection Topography in Schizophrenia Revealed with State-Space Analysis of EEG

Martin Hasler, Oscar De Feo, Reto Meuli, Mahdi Jalili, Kim Do

Background The dysconnection hypothesis has been proposed to account for pathophysiological mechanisms underlying schizophrenia. Widespread structural changes suggesting abnormal connectivity in schizophrenia have been imaged. A functional counterpart of t ...

2007

Multisensory Interactions within Human Primary Cortices Revealed by BOLD Dynamics

Jean-Philippe Thiran, Reto Meuli, Clotaire Michel

Whether signals from different sensory modalities converge and interact within primary cortices in humans is unresolved, despite emerging evidence in animals. This is partially because of debates concerning the appropriate analyses of functional magnetic r ...

2007

How much confidence do we have in a MRI tractography experiment?

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli

When performing a tractography experiment it is essential to know whether a reconstructed tract results from the diffusion signal itself or from some random effect or noise. In this study, we introduce a way to associate to every connection a confidence le ...

IEEE2007

Deriving scalar maps from Diffusion Spectrum MRI

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Van Jay Wedeen, Leila Cammoun

Whole brain DSI acquisitions are now clinically feasible. It is therefore necessary to have scalar maps available in order to easily visualize summary statistics of the full 3D diffusion pdf available in every voxel. We show how to derive from DSI not only ...

IEEE2007

A method to study alterations in networks of structural connectivity

Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Leila Cammoun

IEEE2007

Localization of electrodes in the subthalamic nucleus on magnetic resonance imaging

Jean-Philippe Thiran, Reto Meuli

Object. The authors describe a new method of localizing electrodes on magnetic resonance (MR) images and focus on the positions of both the most efficient contact and the electrode related to the MR imaging target. Methods. Thirty-one patients who had unde ...

2007

A level set method for segmentation of the thalamus and its nuclei in DT-MRI

Jean-Philippe Thiran, Xavier Bresson, Patric Hagmann, Reto Meuli, Lisa Jonasson

2007

Mapping Human Whole-Brain Structural Networks with Diffusion MRI

Patrick Thiran, Jean-Philippe Thiran, Xavier Gigandet, Patric Hagmann, Reto Meuli, Maciej Kurant, Van Jay Wedeen

Understanding the large-scale structural network formed by neurons is a major challenge in system neuroscience. A detailed connectivity map covering the entire brain would therefore be of great value. Based on diffusion MRI, we propose an efficient methodo ...

2007

Visuo-motor pathways in humans revealed by event-related fMRI

Jean-Philippe Thiran, Reto Meuli, Clotaire Michel

Whether different brain networks are involved in generating unimanual responses to a simple visual stimulus presented in the ipsilateral versus contralateral hemifield remains a controversial issue. Visuo-motor routing was investigated with event-related f ...

2006

A Cross Validation Study of Deep Brain Stimulation Targeting: From Experts to Atlas-Based, Segmentation-Based and Automatic Registration Algorithms

Jean-Philippe Thiran, Meritxell Bach Cuadra, Olivier Cuisenaire, Reto Meuli, Francisco Javier Sanchez Castro

Validation of image registration algorithms is a difficult task and open-ended problem, usually application-dependent. In this paper we focus on deep brain stimulation (DBS) targeting for the treatment of movement disorders like Parkinson's disease and ess ...

Institute of Electrical and Electronics Engineers2006

Understanding Diffusion MR Imaging Techniques: From Scalar Diffusion-weighted Imaging to Diffusion Tensor Imaging and Beyond

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Lisa Jonasson, Van Jay Wedeen

The complex structural organization of the white matter of the brain can be depicted in vivo in great detail with advanced diffusion magnetic resonance (MR) imaging schemes. Diffusion MR imaging techniques are increasingly varied, from the simplest and mos ...

2006

Human auditory belt areas specialized in sound recognition: a functional magnetic resonance imaging study

Jean-Philippe Thiran, Reto Meuli, Dragana Viceic

The human primary auditory cortex is surrounded by at least six other, anatomically distinct areas that process auditory information. We have investigated their specialization with respect to sound recognition or sound localization with triple epoch functi ...

2006

Hand preference and sex shape the architecture of language networks

Jean-Philippe Thiran, Patric Hagmann, Reto Meuli, Leila Cammoun

In right-handed subjects, language processing relies predominantly on left hemisphere networks, more so in men than in women, and in right- versus left-handers. Using DT-MRI tractography, we have shown that right-handed men are massively interconnected bet ...

Wiley2006

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