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Djalel Eddine Meskaldji

Cette personne n’est plus à l’EPFL

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Publications associées (39)

The control of the scaled false discovery rate, a flexible and comprehensive error control and a powerful theoretical tool in multiple testing

Stephan Morgenthaler, Djalel Eddine Meskaldji, Dimitri Nestor Alice Van De Ville

Given the large number of papers written over the last ten years on error controls in high dimensional multiple testing, it would be worthwhile to consider a single comprehensive technique that allows user flexibility in error control when dealing with big ...

2015

Improved statistical evaluation of group differences in connectomes by screening-filtering strategy with application to study maturation of brain connections between childhood and adolescence

Stephan Morgenthaler, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Patric Hagmann, Dimitri Nestor Alice Van De Ville, David Paul Roger Romascano

Detecting local differences between groups of connectomes is a great challenge in neuroimaging, because the large number of tests that have to be performed and the impact on multiplicity correction. Any available information should be exploited to increase ...

Elsevier2015

Statistical methods for comparing brain connectomes at different scales

Stephan Morgenthaler, Djalel Eddine Meskaldji, Dimitri Nestor Alice Van De Ville

Physiological Brain connectivity and spontaneous interaction between regions of interest of the brain can be represented by a matrix (full or sparse) or equivalently by a complex network called connectome. This representation of brain connectivity is adopt ...

SPIE-Int Soc Optical Engineering2015

Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits

Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alexis Roche, Ying-Chia Lin

Conventional magnetic resonance imaging (MRI) of patients with multiple sclerosis provides only limited insights into the nature of brain tissue damage with modest clinical-radiological correlations. In this study, quantitative and semi-quantitative MRI te ...

2014

Cerebellar Connectomics Provide New Biomarkers in Early Multiple Sclerosis

Jonas Richiardi, Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Dimitri Nestor Alice Van De Ville, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche, Ying-Chia Lin

The cerebellum is involved in multiple sclerosis (MS), but its implication in early phases is still poorly understood. We investigated structural and functional cerebellar connectivity alterations in early and minimally impaired MS patients, and their corr ...

2014

Multiple Sclerosis Lesion Fingerprint Using Multicontrast MRI

Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alexis Roche, Ying-Chia Lin

Conventional magnetic resonance imaging (MRI) measures of multiple sclerosis patients provide limited information about the nature and the extent of brain damage and repair. We established a clinically compatible protocol including quantitative MRI techniq ...

2014

Advanced MRI unravels the nature of tissue alterations in early multiple sclerosis

Gloria Menegaz, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Guillaume Bonnier, David Paul Roger Romascano, Gunnar Krüger, Cristina Granziera, Alexis Roche, Ying-Chia Lin

In patients with multiple sclerosis (MS), conventional magnetic resonance imaging (MRI) provides only limited insights into the nature of brain damage with modest clinic-radiological correlation. In this study, we applied recent advances in MRI techniques ...

2014

Comparing connectomes across subjects and populations at different scales

Stephan Morgenthaler, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Patric Hagmann, Alessandra Griffa, Elda Fischi Gomez

Brain connectivity can be represented by a network that enables the comparison of the different patterns of struc- tural and functional connectivity among individuals. In the literature, two levels ofstatistical analysis have been con- sidered in comparing ...

2013

Multiple Comparison Procedures for Large Correlated Data with Application to Brain Connectivity Analysis

Djalel Eddine Meskaldji

Recent developments in medical imaging and image analysis allow the determination of interregional brain connectivity through diffusion Magnetic Resonance Imaging (MRI) tractography. The brain connectivity is represented by a connection matrix where each c ...

EPFL2013

Micro-Structural Brain Alterations in Aviremic HIV+ Patients with Minor Neurocognitive Disorders: A Multi-Contrast Study at High Field

Djalel Eddine Meskaldji, Reto Meuli, François Lazeyras, Gunnar Krüger, Tobias Kober, Cristina Granziera, Alessandro Daducci, Alexis Roche

Objective Mild neurocognitive disorders (MND) affect a subset of HIV+ patients under effective combination antiretroviral therapy (cART). In this study, we used an innovative multi-contrast magnetic resonance imaging (MRI) approach at high-field to assess ...

Public Library of Science2013

Mapping the human connectome at multiple scales with diffusion spectrum MRI

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Xavier Gigandet, Patric Hagmann, Reto Meuli, Leila Cammoun, Olaf Sporns, Kim Do

The global structural connectivity of the brain, the human connectome, is now accessible at millimeter scale with the use of MRI. In this paper, we describe an approach to map the connectome by constructing normalized whole-brain structural connection matr ...

Elsevier2012

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast study at high field

Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

2012

A new early and automated MRI-based predictor of motor improvement after stroke

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Reto Meuli, Nouchine Hadjikhani, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche, Richard Frackowiak

Objectives: In this study, we investigated the structural plasticity of the contralesional motor network in ischemic stroke patients using diffusion magnetic resonance imaging (MRI) and explored a model that combines a MRI-based metric of contralesional ne ...

2012

Microstructural alterations in the brain of well treated HIV+ patients with minor neurocognitive disorders: a multi-contrast MRI study at 3T

Djalel Eddine Meskaldji, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Alexis Roche

2012

High b-value diffusion-weighted imaging: a sensitive method to reveal white matter differences in schizophrenia

Pierre Marquet, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Patric Hagmann, Reto Meuli, Philipp Baumann, Leila Cammoun

Over the last ten years, Diffusion-weighted Imaging (DWI) has become an important tool to investigate white matter (WM) anomalies in schizophrenia. Despite technological improvement and the exponential use of this technique, discrepancies remain and little ...

Elsevier2012

Adaptive Strategy for the Statistical Analysis of Connectomes

Stephan Morgenthaler, Jean-Philippe Thiran, Djalel Eddine Meskaldji, Patric Hagmann, Reto Meuli, Leila Cammoun

We study an adaptive statistical approach to analyze brain networks represented by brain connection matrices of interregional connectivity (connectomes). Our approach is at a middle level between a global analysis and single connections analysis by conside ...

Public Library of Science2011

A comprehensive error rate for multiple testing

Stephan Morgenthaler, Jean-Philippe Thiran, Djalel Eddine Meskaldji

In multiple testing, a variety of control metrics have been introduced such as the family-wise error rate (FWER), the False Discovery Rate (FDR), False Exceedence Rate (FER), etc. We found a way to embed these metrics into a continuous family of control me ...

2011

Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Xavier Gigandet, Reto Meuli, Gunnar Krüger, Cristina Granziera, Alessandro Daducci, Leila Cammoun

There is growing interest in understanding the role of the non-injured contra-lateral hemisphere in stroke recovery. In the experimental field, histological evidence has been reported that structural changes occur in the contra-lateral connectivity and cir ...

2011

GLOBAL AND LOCAL CONNECTIVITY CHANGES IN SCHIZOPHRENIA INVESTIGATED BY DIFFUSION CONNECTOME

Jean-Philippe Thiran, Djalel Eddine Meskaldji, Xavier Gigandet, Patric Hagmann, Reto Meuli, Leila Cammoun

Elsevier2010

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