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Arnaud Bertsch

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Publications associées (94)

Facile fabrication of nanofluidic diode membranes using anodic aluminium oxide

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Oscar Vazquez Mena, Songmei Wu

Active control of ion transport plays important roles in chemical and biological analytical processes. Nanofluidic systems hold the promise for such control through electrostatic interaction between ions and channel surfaces. Most existing experiments rely ...

Royal Soc Chemistry2012

Microfluidic synthesis of chitosan-based nanoparticles for fuel cell applications

Philippe Renaud, Arnaud Bertsch, Fatemeh Sadat Majedi, Mohammad Mahdi Hasani-Sadrabadi, Mojtaba Taghipoor

A microfluidic platform is developed for the synthesis of monodisperse, 100 nm, chitosan based nanoparticles using nanogelation with ATP. The resulting nanoparticles tuned and enhanced transport and electrochemical properties of Nafion based nanocomposite ...

Royal Society of Chemistry2012

Simulations to study spatial extent of stimulation and effect of electrode–tissue gap in subretinal implants

Philippe Renaud, Arnaud Bertsch, Sri Harsha Kasi Raj

We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode–tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to ...

Elsevier2011

Instrumented Prosthesis for Knee Implants Monitoring

Steve Tanner, Kamiar Aminian, Philippe Renaud, Catherine Dehollain, Arnaud Bertsch, Peter Ryser, Eric Meurville, Hooman Dejnabadi, Pierre-André Farine, Oguz Atasoy, Brigitte Jolles-Haeberli, Arash Arami, Willyan Hasenkamp Carreira, Shafqat Ali, Matteo Simoncini

In this work we present an instrumented smart knee prosthesis for in-vivo measurement of forces and kinematics. Studying the constraints, we designed minimal sensory systems to be placed in the polyethylene part of the prosthesis. The magnetic sensors and ...

IEEE2011

Simulation of epiretinal prostheses - Evaluation of geometrical factors affecting stimulation thresholds

Philippe Renaud, Grégoire Cosendai, Arnaud Bertsch, Sri Harsha Kasi Raj, Willyan Hasenkamp Carreira

Background An accurate understanding of the electrical interaction between retinal prostheses and retinal tissue is important to design effective devices. Previous studies have used modelling approaches to simulate electric fields generated by epiretinal p ...

BioMed Central2011

Distinguishing drug-induced minor morphological changes from major cellular damage via label-free impedimetric toxicity screening

Philippe Renaud, Arnaud Bertsch, Sri Harsha Kasi Raj, Robert Meissner, Bilge Eker

We present a novel perfusion-based microfluidic platform for label-free drug toxicity screening which can single out non-lethal morphological changes from cellular death using electrical impedance spectroscopy. Minor cellular changes such as cell-cell cont ...

2011

Direct measurement of diffusing proteins in nanochannels using fluorescence correlation spectroscopy

Philippe Renaud, Arnaud Bertsch, Theo Lasser, Nicolas Durand, Raphaël Goetschmann

Transport of proteins in liquid-filled nanometer-sized apertures with charged surfaces based on both diffusion and convective flow is investigated with the use of fluorescence correlation spectroscopy. The measured fluctuations of fluorescence allow the ev ...

Elsevier2009

Direct Observation of Transitions between Surface-Dominated and Bulk Diffusion Regimes in Nanochannels

Philippe Renaud, Arnaud Bertsch, Theo Lasser, Nicolas Durand, Claudio Dellagiacoma, Raphaël Goetschmann

The diffusion of charged proteins in liquid-filled nanometer-sized apertures with charged surfaces has been investigated with fluorescence correlation spectroscopy (FCS). Based on a two-dimensional (2D) multicomponent diffusion model, key parameters such a ...

2009

Wireless contact lens sensor for intra ocular pressure monitoring: assessment on enucleated pig eyes

Matteo Leonardi, André Mermoud, Philippe Renaud, Arnaud Bertsch

Purpose: Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS). Methods: The wireless CLS is a disposable silicone soft co ...

2009

in vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays

Philippe Renaud, Arnaud Bertsch, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun

The goal of this experiment was to determine the electrical properties of the tissue reaction to implanted microelectrode arrays. We describe a new method of analyzing electrical impedance spectroscopy data to determine the complex impedance of the tissue ...

2009

Fluorine based plasma treatment of biocompatible silicone elastomer. Effect of temperature on etch rate and surface properties

Arnaud Bertsch, Cyrille Hibert

This paper describes F-based dry etching and resulting surface properties of biocompatible silicone elastomer. The etch rate of polysiloxane and surface morphology was found to be highly temperature dependent. An increase in temperature results in a signif ...

2008

Healthy Aims: Developing new medical implants and diagnostic equipment

Arnaud Bertsch

Healthy Aims is a 23- million, four-year project, funded under the EU's information society technology sixth framework program to develop intelligent medical implants and diagnostic systems (www.healthyaims.org). The project has 25 partners from 10 countri ...

2008

Demonstration of cortical recording using novel flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun, Karen Cheung

We present the fabrication, characterization, use in cortical recording and histological results of a flexible implantable neural probe. The microfabricated device is implemented in polyimide and platinum providing mechanical flexibility, high quality elec ...

2008

Direct Measurement of Effective Diffusion Coefficients in Nanochannels Using Steady-State Dispersion Effects

Philippe Renaud, Arnaud Bertsch, Mina Todorova, Nicolas Durand

We present a method to measure effective diffusion coefficients of fluorescently labeled molecules inside a nanofluidic system. Molecules with small diffusion coefficients show a larger lateral dispersion than highly diffusive species, which is counterintu ...

American Institute of Physics2007

Demonstration of cortical recording and reduced inflammatory response using flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun, Karen Cheung

2007

Assessment on Enucleated Pig Eyes of a Minimally Invasive Contact Lens Sensor for IOP Monitoring

Matteo Leonardi, André Mermoud, Philippe Renaud, Arnaud Bertsch

2007

Controlled Release Drug Coatings on Flexible Neural Probes

Philippe Renaud, Arnaud Bertsch, Jeffrey Alan Hubbell, André Mercanzini, Philippe Colin, Jean-Charles Bensadoun

We present the development, characterization and in vivo validation of a novel drug eluting coating that has been applied to flexible neural probes. The coating consists of drug eluting nanoparticles loaded with an anti-inflammatory drug embedded in a biod ...

2007

Contraction measurements of cardiomyocytes grown on silicon cantilevers

Philippe Renaud, Arnaud Bertsch, Mina Todorova, Philipp Stücklin

2007

The effect of biodegradable drug release coatings on the electrical characteristrics of neural electrodes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, Jeffrey Alan Hubbell, André Mercanzini

2007

Technology developments to initiate a next generation of Cochlear Implants

Arnaud Bertsch, André Mercanzini

In the framework of the EU-supported research project Healthy Aims, we developed a range of novel electrode arrays and related technologies for use in hearing prosthesis. This paper summarizes our ongoing research activities on alternative electrode manufa ...

IEEE2007

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