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Arnaud Bertsch

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Publications associées (94)

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Volcano-Shaped Scanning Probe Microscopy Probe for Combined Force-Electrogram Recordings from Excitable Cells

Philippe Renaud, Arnaud Bertsch, Georg Fantner, Benoît Xavier Emmanuel Desbiolles, Mélanie Thérèse Marie Hannebelle

Atomic force microscopy based approaches have led to remarkable advances in the field of mechanobiology. However, linking the mechanical cues to biological responses requires complementary techniques capable of recording these physiological characteristics ...

AMER CHEMICAL SOC2020

Breaking one into three: Surface-tension-driven droplet breakup in T-junctions

Philippe Renaud, Arnaud Bertsch, François Gallaire, Daniel Migliozzi, Yves-Marie François Ducimetière, Jiande Zhou, Ludovic Pierre Gustave Keiser

Droplet breakup is an important phenomenon in the field of microfluidics to generate daughter droplets. In this work, a novel breakup regime in the widely studied T-junction geometry is reported, where the pinch-off occurs laterally in the two outlet chann ...

AMER PHYSICAL SOC2023

Field effect modulated nanofluidic diode membrane based on Al2O3/W heterogeneous nanopore arrays

Philippe Renaud, Arnaud Bertsch, Jürgen Brugger, Fabien Patrick Wildhaber, Songmei Wu

We developed Al2O3/W heterogeneous nanopore arrays for field effect modulated nanofluidic diodes. They are fabricated by transferring self-organized nanopores of anodic aluminium oxide into a W thin film. The nanopores are ∼20 nm in diameter and 400 nm in ...

American Institute of Physics2013

Polyimide microfluidic devices with integrated nanoporous filtration areas manufactured by micromachining and ion track technology

Philippe Renaud, Arnaud Bertsch, Stefan Metz

This paper reports on polyimide microfluidic devices fabricated by photolithography and a layer transfer lamination technology. The microchannels are sealed by laminating an uncured polyimide film on a partially cured layer and subsequent imidization. Sele ...

2004

Aperture-Controlled Fabrication of All-Dielectric Structural Color Pixels

Philippe Renaud, Arnaud Bertsch, Olivier Martin, Daniel Migliozzi, Clémentine Sophie Sarah Lipp, Evgenii Glushkov, Hsiang-Chu Wang, Audrey Zoé Marie Jacquillat

While interference colors have been known for a longtime, conventionalcolor filters have large spatial dimensions and cannot be used tocreate compact pixelized color pictures. Here we report a simple yetelegant interference-based method of creating microsc ...

AMER CHEMICAL SOC2023

Controlled Release Drug Coatings on Flexible Neural Probes

Philippe Renaud, Arnaud Bertsch, Jeffrey Alan Hubbell, André Mercanzini, Philippe André Guy Colin, Jean-Charles Bensadoun

We present the development, characterization and in vivo validation of a novel drug eluting coating that has been applied to flexible neural probes. The coating consists of drug eluting nanoparticles loaded with an anti-inflammatory drug embedded in a biod ...

2007

3D Lipid Microrobots for Simultaneous Delivery of Lipophilic and Hydrophilic Drugs

Arnaud Bertsch, Jürgen Brugger, Jongeon Park

This study presents the development of a 3D lipid microhelix capable of simultaneously delivering drugs with different characteristics, including water-soluble and poorly water-soluble drugs. Lipid microhelix encapsulating magnetic nanoparticles (MNPs) and ...

IEEE2025

Instrumented Knee Prosthesis for Force and Kinematics Measurements

Steve Tanner, Kamiar Aminian, Philippe Renaud, Catherine Dehollain, Arnaud Bertsch, Peter Ryser, Eric Meurville, Pierre-André Farine, Oguz Atasoy, Brigitte Jolles-Haeberli, Arash Arami, Willyan Hasenkamp Carreira, Shafqat Ali, Matteo Simoncini

In this work, we present the general concept of an instrumented smart knee prosthesis for in-vivo measurement of forces and kinematics. This system can be used for early monitoring of the patient after implantation and prevent possible damage to the prosth ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Wireless contact lens sensor for intra ocular pressure monitoring: assessment on enucleated pig eyes

Matteo Leonardi, André Mermoud, Philippe Renaud, Arnaud Bertsch

Purpose: Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS). Methods: The wireless CLS is a disposable silicone soft co ...

2009

In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system

Philippe Renaud, Arnaud Bertsch, Philippe André Guy Colin, Bernard Schneider, Guillaume Cédric Yves Petitpierre

Direct collection of extracellular fluid (ECF) plays a central role in the monitoring of neurological disorders. Current approaches using microdialysis catheters are however drastically limited in term of temporal resolution. Here we show a functional in v ...

Nature Publishing Group2017

Microstructured plastic scintillators for pencil beam profiling in proton-therapy accelerators

Arnaud Bertsch, Alessandro Mapelli, Fabrizio Carbone, Simone Gargiulo, Veronica Leccese, Michele Caldara, Samuele Bisi

A novel beam profiler based on microstructured scintillation resin is presented. The detector consists of a bundle of waveguides, featuring an active area of 30 x 30 mm2 with a fill factor of 50% and a pitch of 400 mu m. This configuration is obtained by c ...

Elsevier2024

Cell-Imprinted Substrates Modulate Differentiation, Redifferentiation, and Transdifferentiation

Philippe Renaud, Arnaud Bertsch, Leila Montazeri, Mojtaba Taghipoor, Omid Mashinchian

Differentiation of stem cells into mature cells through the use of physical approaches is of great interest. Here, we prepared smart nanoenvironments by cell-imprinted substrates based on chondrocytes, tenocytes, and semifibroblasts as templates and demons ...

Amer Chemical Soc2016

Simulations to study spatial extent of stimulation and effect of electrode–tissue gap in subretinal implants

Philippe Renaud, Arnaud Bertsch, Sri Harsha Kasi Raj

We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode–tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to ...

Elsevier2011

Dielectrophoretic Traps for Efficient Bead and Cell Trapping and Formation of Aggregates of Controlled Size and Composition

Philippe Renaud, Arnaud Bertsch, Clémentine Sophie Sarah Lipp

We present a microfluidic dielectrophoretic-actuated system designed to trap chosen single-cell and form controlled cell aggregates. A novel method is proposed to characterize the efficiency of the dielectrophoretic trapping, considering the flow speed but ...

2022

Demonstration of cortical recording using novel flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, Marc Jasper Boers, André Mercanzini, Philippe André Guy Colin, Jean-Charles Bensadoun, Karen Cheung

We present the fabrication, characterization, use in cortical recording and histological results of a flexible implantable neural probe. The microfabricated device is implemented in polyimide and platinum providing mechanical flexibility, high quality elec ...

2008

Feedback-free microfluidic oscillator with impinging jets

Philippe Renaud, Arnaud Bertsch, François Gallaire, Margaux Catherine Marie Duchamp, Alessandro Bongarzone

The present paper describes a microfluidic oscillator based on facing impinging jets and operating in laminar flow conditions. Using appropriate microchannel configurations, pulsatile liquid flows are generated at the microscale from steady and equal inlet ...

2020

Microfluidics: A New Layer of Control for Extrusion-Based 3D Printing

Philippe Renaud, Arnaud Bertsch, Ludovic Serex

Advances in 3D printing have enabled the use of this technology in a growing number of fields, and have started to spark the interest of biologists. Having the particularity of being cell friendly and allowing multimaterial deposition, extrusion-based 3D p ...

2018

Rapid exocytosis kinetics measured by amperometry within volcano microelectrodes

Philippe Renaud, Arnaud Bertsch, Nicolas Grégoire Maïno

For over 30 years, carbon fiber microelectrodes have been the gold standard for measurements related to exocytosis and more generally to the processes taking place at the synaptic level. However, this method has a low throughput and molecules can escape de ...

ROYAL SOC CHEMISTRY2023

Design and test of a MEMS strain-sensing device for monitoring artificial knee implants

Kamiar Aminian, Alexandre Terrier, Philippe Renaud, Arnaud Bertsch, Arash Arami, Willyan Hasenkamp Carreira

This paper describes the development of a polyimide-based MEMS strain-sensing device. Finite element analysis was used to investigate an artificial knee implant and assist on device design and to optimize sensing characteristics. The sensing element of the ...

Springer2013

SU-8 nanocomposite coatings with improved tribological performance for MEMS

Heinrich Hofmann, Stefano Mischler, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

The increasing interests in micro-electro-mechanical systems (MEMS) has raised the requirement for photoresist materials with improved friction and wear properties for mechanically loaded 3D shaped microstructures. In this work, SU8 photoresist layers rein ...

2006