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Claudio Bruschini

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Publications associées (185)

Ten years of biophotonics single-photon SPAD imager applications: retrospective and outlook, Multiphoton Microscopy in the Biomedical Sciences XVII

Claudio Bruschini, Edoardo Charbon, Harald Arjan Robert Homulle

SPAD (single-photon avalanche diode) arrays are single-photon imagers that can provide unparalleled timeresolved sensing performance. Since their inception in standard CMOS technologies (2003), a host of architectures and target applications have been expl ...

2017

EMG Pattern Recognition Using Decomposition Techniques for Constructing Multiclass Classifiers

Christian Enz, Claudio Bruschini, Jörn Justiz, Huaiqi Huang, Tao Li

To improve the dexterity of multi-functional myoelectric prosthetic hand, more accurate hand gesture recognition based on surface electromyographic (sEMG) signal is needed. This paper evaluates two types of time-domain EMG features, one independent feature ...

IEEE2016

Nonuniformity Analysis of a 65-kpixel CMOS SPAD Imager

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Ivan Michel Antolovic

While CMOS single-photon avalanche diode (SPAD) technology has steadily advanced, improving noise, timing resolution, and sensitivity, spatial resolution has been increasing as well. The increase in the number of pixels has made a comprehensive analysis of ...

IEEE-Inst Electrical Electronics Engineers Inc2016

Photon-Counting Arrays for Time-Resolved Imaging

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Ivan Michel Antolovic

The paper presents a camera comprising 512 x 128 pixels capable of single-photon detection and gating with a maximum frame rate of 156 kfps. The photon capture is performed through a gated single-photon avalanche diode that generates a digital pulse upon p ...

MDPI2016

LinoSPAD: a time-resolved 256x1 CMOS SPAD line sensor system featuring 64 FPGA-based TDC channels running at up to 8.5 giga-events per second

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Harald Arjan Robert Homulle

LinoSPAD is a reconfigurable camera sensor with a 256x 1 CMOS SPAD (single-photon avalanche diode) pixel array connected to a low cost Xilinx Spartan 6 FPGA. The LinoSPAD sensor's line of pixels has a pitch of 24 pm and 40% fill factor. The FPGA implements ...

Spie-Int Soc Optical Engineering2016

GigaRad total ionizing dose and post-irradiation effects on 28 nm bulk MOSFETs

Christian Enz, Claudio Bruschini, Federico Faccio, Farzan Jazaeri, Chunmin Zhang, Alessandro Pezzotta

The DC performance of both n- and pMOSFETs fabricated in a commercial-grade 28 nm bulk CMOS process has been studied up to 1 Grad of total ionizing dose and at post-irradiation annealing. The aim is to assess the potential use of such an advanced CMOS tech ...

IEEE2016

Analyzing blinking effects in super resolution localization microscopy with single-photon SPAD imagers

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Ivan Michel Antolovic

For many scientific applications, electron multiplying charge coupled devices (EMCCDs) have been the sensor of choice because of their high quantum efficiency and built-in electron amplification. Lately, many researchers introduced scientific complementary ...

Spie-Int Soc Optical Engineering2016

Impact of GigaRad Ionizing Dose on 28 nm bulk MOSFETs for future HL-LHC

Christian Enz, Claudio Bruschini, Federico Faccio, Farzan Jazaeri, Chunmin Zhang, Alessandro Pezzotta

The Large Hadron Collider (LHC) running at CERN will soon be upgraded to increase its luminosity giving rise to radiations reaching the level of GigaRad Total Ionizing Dose (TID). This paper investigates the impact of such high radiation on transistors fab ...

IEEE2016

Compact solid-state CMOS single-photon detector array for in vivo NIR fluorescence lifetime oncology measurements

Claudio Bruschini, Edoardo Charbon, Krisztian Homicsko, François Eric Powolny, Riccardo Sinisi, Harald Arjan Robert Homulle, David Li

In near infrared fluorescence-guided surgical oncology, it is challenging to distinguish healthy from cancerous tissue. One promising research avenue consists in the analysis of the exogenous fluorophores' lifetime, which are however in the (sub-)nanosecon ...

2016

Fundamentals of a scalable network in SPADnet-based PET systems

Claudio Bruschini, Edoardo Charbon

2015

Automatic Hand Phantom Map Detection Methods

Christian Enz, Claudio Bruschini, Jörn Justiz, Huaiqi Huang, Tao Li

Many amputees have maps of referred sensation from their missing hand on their residual limb (phantom maps). This skin area can serve as a target for providing amputees with tactile sensory feedback. Providing tactile feedback on the phantom map can improv ...

2015

EndoTOFPET-US: an endoscopic Positron Emission Tomography detector for a novel multimodal medical imaging tool

Claudio Bruschini

2015

A 5x5 SPADnet Digital SiPM Tile for PET Applications

Claudio Bruschini, Edoardo Charbon, Gabor Nemeth

SPADnet is a sensor platform for the detection and processing of gamma photons generated in a PET system. SPADnet uses the novel technique of deferred coincidence detection, whereas timestamps associated with gamma events and their energy are routed at hig ...

2015

Fluorescence lifetime imaging to differentiate bound from unbound ICG-cRGD both in vitro and in vivo

Claudio Bruschini, Edoardo Charbon, François Eric Powolny, Riccardo Sinisi, Harald Arjan Robert Homulle

Excision of the whole tumor is crucial, but remains difficult for many tumor types. Fluorescence lifetime imaging could be helpful intraoperative to differentiate normal from tumor tissue. In this study we investigated the difference in fluorescence lifeti ...

Spie-Int Soc Optical Engineering2015

EndoTOFPET-US – A Miniaturised Calorimeter for Endoscopic Time-of-Flight Positron Emission Tomography

Claudio Bruschini

IOP2015

EndoTOFPET-US a High Resolution Endoscopic PET-US Scanner Used for Pancreatic and Prostatic Clinical Exams

Claudio Bruschini

2014

SPADnet network modeling, simulation and emulation

Claudio Bruschini, Edoardo Charbon, Esteban Venialgo Araujo

IEEE2014

SPADs for quantum random number generators and beyond

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Francesco Regazzoni

2014

Development of EndoTOFPET-US, a multi-modal endoscope for ultrasound and time of flight positron emission tomography

Claudio Bruschini

2014

SPADnet: a fully digital, scalable and networked photonic component for time-of-flight PET applications

Claudio Bruschini, Edoardo Charbon, John Richard Walker, Gabor Nemeth

The SPADnet FP7 European project is aimed at a new generation of fully digital, scalable and networked photonic components to enable large area image sensors, with primary target gamma-ray and coincidence detection in (Time-of-Flight) Positron Emission Tom ...

Spie-Int Soc Optical Engineering2014

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