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Heinrich Hofmann

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Publications associées (121)

Drug loading of porous coating

Heinrich Hofmann, Laurent-Dominique Piveteau

Porous coating for the controlled release of drugs, said coating comprising a porous structure with pores adapted to act as reservoirs or as passages for a drug, in such a way that said drug can move from the external environment to/from or through said po ...

2006

Uptake and Biocompatibility of Functionalized Poly(vinylalcohol) Coated Superparamagnetic Maghemite Nanoparticles by Synoviocytes In Vitro

Heinrich Hofmann, Alke Fink, Benedikt Steitz

Superparamagnetic iron oxide nanoparticles (SPION) were coated with either Polyvinyl alcohol (PVA) or Vinyl alcohol/vinyl amine copolymer and further functionalized with the fluorochromes Cy3.5 or Texas Red. A colloidally stable suspension of nanoparticles ...

2006

Precipitation of Nanostructured Copper Oxalate: Substructure and Growth Mechanism

Paul Bowen, Heinrich Hofmann, Jacques Lemaître, Lucica Soare

The possibility of controlling materials properties by tailoring their substructure at the nanometer scale is a current topic of great interest. To do so, a fundamental understanding of the growth mechanism is of key importance and an analytical challenge ...

2006

Formation and Drying of Colloidal Crystals Using Nanosized Silica Particles

Paul Bowen, Heinrich Hofmann, Frédéric Juillerat

Much interest has been generated in the fabrication of colloidal crystals from suspensions because of the promise of photonic band gap applications. However, since the case of small, nonsedimenting colloidal particles indeed remains rather rarely treated, ...

2006

Anisotropic nanoporous coating

Heinrich Hofmann, Laurent-Dominique Piveteau

Porous coating production, e.g. for medical implant, involves depositing first mono-layer(s) of temporary particles on surface, depositing coating(s) on particles, eliminating temporary particles forming pores, and coating fixation step NOVELTY - Producing ...

2006

Enhancement of the efficiency of non-viral gene delivery by application of pulsed magnetic field

Heinrich Hofmann, Alke Fink, Benedikt Steitz

New approaches to increase the efficiency of non-viral gene delivery are still required. Here we report a simple approach that enhances gene delivery using permanent and pulsating magnetic fields. DNA plasmids and novel DNA fragments (PCR products) contain ...

2006

Plastic Micropump with ferrofluidic actuation

Christophe Yamahata, Heinrich Hofmann, Mathieu Chastellain, Martinus Gijs, Alke Fink, Virendra Kumar Parashar

Institute of Electrical and Electronics Engineers2005

Intraarticular application of superparamagnetic nanoparticles and their uptake by synovial membrane—an experimental study in sheep

Heinrich Hofmann, Mathieu Chastellain, Alke Fink, Benedikt Steitz

A superparamagnetic iron oxide nanoparticle, coated with polyvinyl alcohol, (PVA-SPION) and its fluorescently functionalized analogue (amino-PVA-Cy3.5-SPION) were compared in vivo as proof of principle for future use in magnetic drug targeting in inflammat ...

2005

Colloidal processing and sintering of nanosized transition aluminas

Paul Bowen, Heinrich Hofmann, Claude Paul Carry, David Luxembourg

The dispersion of nanosized gamma aluminas with high specific surfaces areas (100 m2 /g) and primary particle sizes around 20 nm, using polyacrylic acid, has been investigated. The effect of pH and polymer concentration showed that the highest density gree ...

2005

Methodology description for detection of cellular uptake of PVA coated superparamagnetic iron oxide nanoparticles (SPION) in synovial cells of sheep

Heinrich Hofmann, Mathieu Chastellain, Alke Fink

The detection of superparamagnetic iron oxide nanoparticles (SPION) in synoviocytes is reported. Synoviocytes were incubated for 2, 12, 24 and 48 h with 1.5 mg/ml of PVA coated SPION under the influence of magnets (12 h). Particles were well tolerated by t ...

2005

Fabrication of large-area ordered arrays of nanoparticles on patterned substrates

Paul Bowen, Heinrich Hofmann, Frédéric Juillerat

Many potential applications in nanotechnology require virtually defect-free arrays of nanometre-scale particles over large areas. Guided self-assembly of colloidal particles on patterned templates has been shown to produce ordered arrays of colloidal parti ...

2005

Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system

Heinrich Hofmann

2005

Development of biocompatible functionalized superparamagnetic iron oxide nanoparticles for human cancer cell uptake and intracellular delivery

Heinrich Hofmann, Mathieu Chastellain, Alke Fink, Alessio Ferrari

2005

Conductive SU8 Photoresist for Microfabrication

Heinrich Hofmann, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

A conductive composite photoresist has been developed for the direct photopatterning of electrodes. It is based on a dispersion of silver nanoparticles in SU8, a non-conductive, negative-tone photoresist. Manufactured structures have an electrical conducti ...

2005

Use of seeds to control precipitation of calcium carbonate and determination of seed nature

Marcel Donnet, Nathalie Jongen, Paul Bowen, Heinrich Hofmann, Jacques Lemaître

2005

SU8-silver photosensitive nanocomposite

Heinrich Hofmann, Philippe Renaud, Arnaud Bertsch, Sébastien Jiguet

2004

Particle size investigations of a multistep synthesis of PVA coated superparamagnetic nanoparticles

Heinrich Hofmann, Mathieu Chastellain, Alke Fink

Nanoscaled particles showing superparamagnetic behavior have been intensively studied in the past years for various applications. Nevertheless, the lack of well-defined particles remains an important problem. One of the major challenges is still the large- ...

2004

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Heinrich Hofmann

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Drug loading of porous coating

Uptake and Biocompatibility of Functionalized Poly(vinylalcohol) Coated Superparamagnetic Maghemite Nanoparticles by Synoviocytes In Vitro

Precipitation of Nanostructured Copper Oxalate: Substructure and Growth Mechanism

Formation and Drying of Colloidal Crystals Using Nanosized Silica Particles

Anisotropic nanoporous coating

Enhancement of the efficiency of non-viral gene delivery by application of pulsed magnetic field

Plastic Micropump with ferrofluidic actuation

Intraarticular application of superparamagnetic nanoparticles and their uptake by synovial membrane—an experimental study in sheep

Colloidal processing and sintering of nanosized transition aluminas

Methodology description for detection of cellular uptake of PVA coated superparamagnetic iron oxide nanoparticles (SPION) in synovial cells of sheep

Fabrication of large-area ordered arrays of nanoparticles on patterned substrates

Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system

Development of biocompatible functionalized superparamagnetic iron oxide nanoparticles for human cancer cell uptake and intracellular delivery

Conductive SU8 Photoresist for Microfabrication

Use of seeds to control precipitation of calcium carbonate and determination of seed nature

SU8-silver photosensitive nanocomposite

Particle size investigations of a multistep synthesis of PVA coated superparamagnetic nanoparticles

The fabrication of porous coating using laser spark atomisation

Superparamagnetic iron oxide Nanoparticles for biomedical application: a focus on PVA as a coating

ZnS nanoparticles: Synthesis and Characterization