Recherche

Afficher tous les résultats pour

Accueil

Personne

Gerardo Turcatti

Cette personne a quitté l’EPFL

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (56)

Page 3 sur 3

Improved method of nucleotide detection

Gerardo Turcatti

The invention relates to an additive which can be added to buffers used in nucleotide detection processes and improved methods of nucleic acid sequencing using this additive. In particular the invention relates to use of the additive to improve the efficie ...

2007

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

Christian Heinis, Gerardo Turcatti, Alessandro Angelini, Jonathan Patrice Vesin, Julien Bortoli Chapalay, Manuel Leonardo Merz, Sevan Mleh Habeshian, Mischa Schüttel, Ganesh Kumar Mothukuri, Gontran Sangouard, Cristina Diaz Perlas, Zsolt Bognár

Macrocycles have excellent potential as therapeutics due to their ability to bind challenging targets. However, generating macrocycles against new targets is hindered by a lack of large macrocycle libraries for high-throughput screening. To overcome this, ...

Nature Research2022

A Universal Assay for Aminopeptidase Activity and Its Application for Dipeptidyl Peptidase-4 Drug Discovery

James William Collins, Gerardo Turcatti, Elena Goun, Marc Chambon, Arkadiy Bazhin, Jonathan Patrice Vesin, Julien Bortoli Chapalay

Aminopeptidases, such as dipeptidyl peptidase 4 (DPP-4, CD26), are potent therapeutic targets for pharmacological interventions because they play key roles in many important pathological pathways. To analyze amino-peptidase activity in vitro (including hig ...

AMER CHEMICAL SOC2019

Automated fast label-free quantification of cardiomyocyte dynamics with raw holograms for cardiotoxicity screening

Gerardo Turcatti, Benjamin Rappaz

Traditional cell analysis approaches based on quantitative phase imaging (QPI) necessitate a reconstruction stage, which utilizes digital holography. However, phase retrieval processing can be complicated and time-consuming since it needs numerical reconst ...

Optica Publishing Group2025

Loss of Protein Tyr-phosphorylation During in vitro Storage of Human Erythrocytes: Impact on RBC Morphology

Pierre Marquet, Gerardo Turcatti, Niels Erik Lion, Benjamin Rappaz, Michel Prudent

Wiley-Blackwell2014

Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from

Karl Gademann, Joachim Lingner, Gerardo Turcatti, Cyril Portmann, Damiano Banfi, Emilie Baudat

By using the Telospot assay, 27 different extracts of cyanobacteria were evaluated for telomerase inhibition. All extracts showed varying, but significant activity. We selected Microcystis aeruguinosa PCC 7806 to identify the active compound and a bioassay ...

Wiley-Blackwell2013

Preparation of nucleic acid templates for solid phase amplification

Gerardo Turcatti

The invention relates to a method of preparing template constructs for solid-phase nucleic acid amplification and to use of the templates in methods of solid-phase nucleic acid amplification. The method involves carrying out two ligation reactions: (a) a l ...

2010

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

Gerardo Turcatti, Fabien Kuttler

Viruses are genetically and structurally diverse, and outnumber cells by orders of magnitude. They can cause acute and chronic infections, suppress, or exacerbate immunity, or dysregulate survival and growth of cells. To identify chemical agents with pro- ...

2022

A Label-Free, High-Throughput Phenotypic Screen Of Adipocytic Differentiation Modulators To Accelerate Hematopoietic Recovery

Bart Deplancke, Gerardo Turcatti, Vincent Roland Julien Gardeux, Fabien Kuttler, Vasco Ledebur de Antas de Campos, Damiano Banfi, Pernille Yde Rainer, Aurélien Laurent Jean-Charles Oggier

ELSEVIER SCIENCE INC2022

Gerardo Turcatti

Graph Chatbot

Improved method of nucleotide detection

Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

A Universal Assay for Aminopeptidase Activity and Its Application for Dipeptidyl Peptidase-4 Drug Discovery

Automated fast label-free quantification of cardiomyocyte dynamics with raw holograms for cardiotoxicity screening

Loss of Protein Tyr-phosphorylation During in vitro Storage of Human Erythrocytes: Impact on RBC Morphology

Telomerase Inhibitors from Cyanobacteria: Isolation and Synthesis of Sulfoquinovosyl Diacylglycerols from

Preparation of nucleic acid templates for solid phase amplification

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

A Label-Free, High-Throughput Phenotypic Screen Of Adipocytic Differentiation Modulators To Accelerate Hematopoietic Recovery

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

Novel fluorescence - based approaches to probe ligand recognition and structure of the tachykinin NK2 receptor

Method of Nucleotide Detection

Repurposing drug screen of patient-derived malignant pleural mesothelioma cells reveals potential anti-cancer activity

Development Of A Novel First-In-Class Oral Inhibitor Of The Notch Pathway

Identification of CDC-48 inhibitors in C. elegans

Targeting STING with covalent small-molecule inhibitors