Dominique Pioletti

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Publications associées (190)

Mechanical Interaction Between Fluid And Cell Modulates Fluid Flow Induced Shear Stress

Dominique Pioletti, Lalaonirina Rakotomanana Ravelonarivo, Luc Blecha

2006

Bone tissue engineering using fetal cell therapy

Dominique Pioletti, Lee Ann Laurent-Applegate

Different cell sources for bone tissue engineering are reviewed. In particular, adult cell source strategies have been based on the implantation of unfractionated fresh bone marrow; purified, culture expanded mesenchymal stem cells, differentiated osteobla ...

2006

Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering

Dominique Pioletti, Pierre-Etienne Bourban

Bone is a complex porous composite structure with specific characteristics such as viscoelasticity and anisotropy, both in morphology and mechanical properties. Bone defects are regularly filled with artificial tissue grafts, which should ideally have prop ...

2006

Orthopedic implants as drug delivery systems: a theoretical study

Dominique Pioletti

2006

Bioresorbable composites prepared by supercritical fluid foaming

Dominique Pioletti, Pierre-Etienne Bourban

Bone is a natural composite construct, with a gradient structure going from a loose interconnected cellular core to an outer dense wall, thus minimizing bone weight while keeping a high mechanical resistance. Due to this unique and complex structure, bone ...

2005

How plate positioning impacts the biomechanics of the open wedge tibial osteotomy; a finite element analysis

Dominique Pioletti, Pierre-Etienne Bourban, Luc Blecha

A numerical model of the medial open wedge tibial osteotomy based on the finite element method was developed. Two plate positions were tested numerically. In a configuration, (a), the plate was fixed in a medial position and (b) in an anteromedial position ...

2005

Bioresorbable polymer composites for bone tissue engineering applications

Dominique Pioletti, Pierre-Etienne Bourban

2005

Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells

Dominique Pioletti, Pierre-Etienne Bourban, Boris Hinz

The aim of this investigation was to test the biocompatibility of three-dimensional bioresorbable foams made of poly(L-lactic acid) (PLA), alone or filled with hydroxyapatite (HA) or beta-tricalcium phosphate (beta-TCP), with human primary osteoblasts, usi ...

2005

The effect of bisphosphonates and titanium particles on osteoblasts: an in vitro study

Bastian Peter, Dominique Pioletti

In an attempt to increase the life of cementless prostheses, an hydroxyapatite-coated implant which releases a bisphosphonate has been suggested as a drug-delivery system. Our in vitro study was designed to determine the maximum dose to which osteoblasts c ...

2005

Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration

Bastian Peter, Dominique Pioletti

Despite total hip replacement (THR) gives generally satisfactory results, the quality of outcome in young patients is markedly decreased compared to the average THR outcome. For this population, pharmacological treatment with bisphosphonate would be benefi ...

2005

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