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Concept

Olfactory system

Publications associées (25)

Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease

Hilal Lashuel, Yogesh Singh Chauhan, Florian Lang, Joan Romani Aumedes

Background Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclei ...

BMC2023

First paleoproteome study of fossil fish otoliths and the pristine preservation of the biomineral crystal host

Anders Meibom, Jaroslaw Hubert Stolarski, Jinming Guo

Otoliths are calcium carbonate components of the stato-acoustical organ responsible for hearing and maintenance of the body balance in teleost fish. During their formation, control over, e.g., morphology and carbonate polymorph is influenced by complex ins ...

Nature Portfolio2023

Olfactory modulation of barrel cortex activity during active whisking and passive whisker stimulation

Anthony Pierre Robert Renard

Rodents depend on olfaction and touch to meet many of their fundamental needs. However, the impact of simultaneous olfactory and tactile inputs on sensory representations in the cortex remains elusive. To study these interactions, we recorded large populat ...

Nature Portfolio2022

A study model for reconstructing urban ecological niches

Francesco Mondada, Robert Matthew Mills

The Living Arch is a study model that was designed to showcase our ongoing research into bioactive architectural systems to be inhabited by honeybees. The arch is a synergistic combination of 3D printing and active mycelia growth, created for a museum exhi ...

CRC Press2022

Shedding light on excessive crying in babies

Dimitri Nestor Alice Van De Ville, François Lazeyras, Lorena Gonçalves de Alcântara e Freitas Krikler

Background Excessive and inconsolable crying behavior in otherwise healthy infants (a condition called infant colic (IC)) is very distressing to parents, may lead to maternal depression, and in extreme cases, may result in shaken baby syndrome. Despite the ...

NATURE PUBLISHING GROUP2021

Microfluidic device performing on flow study of serial cell–cell interactions of two cell populations

Philippe Renaud, George Coukos, Alexandre Harari, Thamani Dahoun, Margaux Catherine Marie Duchamp, Clarisse Jeanne Antonia Benoit

In this study we present a novel microfluidic hydrodynamic trapping device to probe the cell–cell interaction between all cell samples of two distinct populations. We have exploited an hydrodynamic trapping method using microfluidics to immobilize a batch ...

2019

Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone

Freddy Radtke

Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent neural stem cells (NSCs). V-SVZ NSCs are a reservoir for new olfactory bulb (OB) neurons that migrate through the rostral migratory stream (RMS). To ...

2018

The gram-negative sensing receptor PGRP-LC contributes to grooming induction in Drosophila

Bruno Lemaitre, Claudine Danielle Patricia Öngen

Behavioral resistance protects insects from microbial infection. However, signals inducing insect hygiene behavior are still relatively unexplored. Our previous study demonstrated that olfactory signals from microbes enhance insect hygiene behavior, and gu ...

Public Library of Science2017

Evolution of Acid-Sensing Olfactory Circuits in Drosophilids

Matteo Dal Peraro

Animals adapt their behaviors to specific ecological niches, but the genetic and cellular basis of nervous system evolution is poorly understood. We have compared the olfactory circuits of the specialist Drosophila sechellia-which feeds exclusively on Mori ...

Elsevier2017

Subject-Independent Odor Pleasantness Classification Using Brain and Peripheral Signals

Touradj Ebrahimi, Jean-Marc Vesin, Eleni Kroupi

Enhanced sensation of reality from multimedia contents can be achieved by creating realistic multimedia environments, using visual, auditory, and olfactory information. Although the affective information from video and audio has been extensively studied, t ...

Ieee-Inst Electrical Electronics Engineers Inc2016

A Graph-Based Formation Algorithm for Odor Plume Tracing

Alcherio Martinoli, Jorge Miguel Dias Almeida Rodrigues Soares

Odor plume tracing is a challenging robotics application, made difficult by the combination of the patchy characteristics of odor distribution and the slow response of the available sensors. This work proposes a graph-based formation control algorithm to c ...

Springer Japan2016

Neuroligin-2 expression in the prefrontal cortex is involved in attention deficits induced by peripubertal stress

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Stamatina Tzanoulinou, Orbicia Riccio Wicht

Emerging evidence indicates that attention deficits, which are frequently observed as core symptoms of neuropsychiatric disorders, may be elicited by early life stress. However, the mechanisms mediating these stress effects remain unknown. The prefrontal c ...

2016

Non-Linear EEG Features for Odor Pleasantness Recognition

Touradj Ebrahimi, Eleni Kroupi, Dionisije Sopic

Since olfactory sense is gaining ground in multimedia applications, it is important to understand the way odor pleasantness is perceived. Although several studies have explored the way odor pleasantness perception influences the power spectral density of t ...

2014

Phase-based manganese enhanced MRI, a new methodology to enhance brain cytoarchitectural contrast and study manganese uptake

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Rajika Maddage

Purpose As the magnetic susceptibility induced frequency shift increases linearly with magnetic field strength, the present work evaluates manganese as a phase imaging contrast agent and investigates the dose dependence of brain enhancement in comparison t ...

Wiley-Blackwell2014

Emergence of Connectivity Motifs in Networks of Model Neurons with Short- and Long-Term Plastic Synapses

Michele Giugliano

Recent experimental data from the rodent cerebral cortex and olfactory bulb indicate that specific connectivity motifs are correlated with short-term dynamics of excitatory synaptic transmission. It was observed that neurons with short-term facilitating sy ...

Public Library of Science2014

Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration

Graham Knott, Liliane Glauser, Elpida Tsika, Shi-Yan Caroline Foo

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant Parkinson's disease (PD). The clinical and neurochemical features of LRRK2-linked PD are similar to idiopathic disease although neuropathology is somewhat heter ...

Elsevier2014

Functional Characterization of the Mouse Olfactory Receptor mOR256-17 in Live Cells

Thamani Dahoun

Olfactory receptors (ORs) constitute the largest family of sensory membrane proteins in mammals. They play a key role within the olfactory system to recognize and discriminate a nearly unlimited number of structurally diverse odorant molecules. The molecul ...

EPFL2013

Noise-enhanced associative memories

Mohammad Amin Shokrollahi, Amin Karbasi, Amir Hesam Salavati

Recent advances in associative memory design through structured pattern sets and graph-based inference algorithms have allowed reliable learning and recall of an exponential number of patterns. Although these designs correct external errors in recall, they ...

2013

General developmental health in the VPA-rat model of autism

Henry Markram, Kamila Markram, Georges Khazen, Mônica Regina Favre

Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal ...

Frontiers Research Foundation2013

Probing Odorant-Mediated Receptor Activation

Olivia Baud

Molecular interactions of odorants with their olfactory receptors (ORs) are of central importance for the mammalian olfactory system to detect and discriminate a large variety of odors with a limited set of receptors. How a particular OR binds and distingu ...

EPFL2012