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Publications associées (29)

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Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis

Johan Auwerx, Antoine Jalil

Mitochondria have emerged as key actors of innate and adaptive immunity. Mitophagy has a pivotal role in cell homeostasis, but its contribution to macrophage functions and host defense remains to be delineated. Here, we showed that lipopolysaccharide (LPS) ...

AMER SOC CLINICAL INVESTIGATION INC2020

Local Vulnerabilities and Global Robustness of Coupled Dynamical Systems on Complex Networks

Melvyn Sandy Tyloo

Coupled dynamical systems are omnipresent in everyday life. In general, interactions between individual elements composing the system are captured by complex networks. The latter greatly impact the way coupled systems are functioning and evolving in time. ...

EPFL2020

A meta-learning approach for genomic survival analysis

Arnout Jan J Devos

RNA sequencing has emerged as a promising approach in cancer prognosis as sequencing data becomes more easily and affordably accessible. However, it remains challenging to build good predictive models especially when the sample size is limited and the numb ...

Nature Research2020

Contact process under renewals II

Thomas Mountford

We continue the study of renewal contact processes initiated in a companion paper, where we showed that if the tail of the interarrival distribution mu is heavier than t(-alpha) for some alpha < 1 (plus auxiliary regularity conditions) then the critical va ...

ELSEVIER2020

Inconsistent relationship between body weight/body mass index prior to total knee arthroplasty and the 12-year survival

Brigitte Jolles-Haeberli

Background: The primary hypothesis was that body weight (BW) and body mass index (BMI) significantly impact the long-term survival rate after implantation of a mobile bearing total knee arthroplasty (TKA). ...

ELSEVIER2019

Revealing Tumor Habitats from Texture Heterogeneity Analysis for Classification of Lung Cancer Malignancy and Aggressiveness

Adrien Raphaël Depeursinge

We propose an approach for characterizing structural heterogeneity of lung cancer nodules using Computed Tomography Texture Analysis (CTTA). Measures of heterogeneity were used to test the hypothesis that heterogeneity can be used as predictor of nodule ma ...

Nature Research2019

The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

Adrien Raphaël Depeursinge

Objective: Stereotactic ablative radiotherapy (SABR) is being increasingly used as a non-invasive treatment for early-stage non-small cell lung cancer (NSCLC). A non-invasive method to estimate treatment outcomes in these patients would be valuable, especi ...

BRITISH INST RADIOLOGY2019

Effect of a second layer on the time to failure of compressed riprap as mountain riverbank protection

Anton Schleiss, Michael Pfister, Mário Jorge Rodrigues Pereira Da Franca, Mona Jafarnejad Chaghooshi

Recently, Jafarnejad, Franca, Pfister, and Schleiss [2017. Time-based failure analysis of compressed riverbank riprap. Journal of Hydraulic Research, 55(2), 224–235. doi: 10.1080/00221686.2016.1212940] presented an experimental study on the stability of co ...

Taylor & Francis Ltd2019

Fast and Accurate Uncertainty Estimation in Chemical Machine Learning

Michele Ceriotti, Félix Benedito Clément Musil, Michael John Willatt, Mikhail Langovoy

We present a scheme to obtain an inexpensive and reliable estimate of the uncertainty associated with the predictions of a machine-learning model of atomic and molecular properties. The scheme is based on resampling, with multiple models being generated ba ...

2019